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  1. Content type: Research article

    In Japan, cognitive behavioral therapy (CBT) for panic disorder (PD) is not well established. Therefore, a feasibility study of the clinical effectiveness and cost-effectiveness of CBT for PD in a Japanese cli...

    Authors: Yoichi Seki, Shinobu Nagata, Takayuki Shibuya, Naoki Yoshinaga, Mizue Yokoo, Hanae Ibuki, Noriko Minamitani, Muga Kusunoki, Yasushi Inada, Nobuko Kawasoe, Soichiro Adachi, Kensuke Yoshimura, Michiko Nakazato, Masaomi Iyo, Akiko Nakagawa and Eiji Shimizu

    Citation: BMC Research Notes 2016 9:458

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    The Erratum to this article has been published in BMC Research Notes 2017 10:86

  2. Content type: Technical Note

    Newly proliferated oligodendrocyte precursor cells (OPCs) migrate and surround lesions of patients with multiple sclerosis (MS) and other demyelinating diseases, but fail to differentiate into oligodendrocytes...

    Authors: Elen S. Rosler, Karen D. Lariosa-Willingham, Jay S. Tung, Jason C. Dugas, Tassie L. Collins and Dmitri Leonoudakis

    Citation: BMC Research Notes 2016 9:444

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  3. Content type: Case report

    Chorea is a rare complication of uncontrolled type II diabetes. We report for the first time in Tanzania a case of type II diabetes presenting with a hyperglycaemia-induced hemichorea.

    Authors: Flora Ruhangisa, Henry Stephen, Jacob Senkondo, Amos Mwasamwaja, Said Kanenda, Saleh Mbarak, Nyasatu Chamba, Kajiru Kilonzo, William Howlett, Isaack Lyaruu and Elichilia Shao

    Citation: BMC Research Notes 2016 9:413

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  4. Content type: Case Report

    Neurosyphilis is defined as any involvement of the central nervous system by the bacterium Treponema pallidum. Movement disorders as manifestations of syphilis have been reported quite rarely.

    Authors: Liis Sabre, Mark Braschinsky and Pille Taba

    Citation: BMC Research Notes 2016 9:372

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  5. Content type: Technical Note

    Wheel running is one of the most widely studied behaviours in laboratory rodents. As a result, improved approaches for the objective monitoring and gathering of more detailed information is increasingly becomi...

    Authors: Taylor Chomiak, Edward W. Block, Andrew R. Brown, G. Campbell Teskey and Bin Hu

    Citation: BMC Research Notes 2016 9:262

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  6. Content type: Research article

    Brain edema is a significant challenge facing clinicians managing severe traumatic brain injury (TBI) in the acute period. If edema reaches a critical point, it leads to runaway intracranial hypertension that,...

    Authors: John D. Finan, Frances S. Cho, Steven G. Kernie and Barclay Morrison III

    Citation: BMC Research Notes 2016 9:160

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  7. Content type: Research article

    In a multicentre, single-arm, observational, phase IV study, we evaluated 24-week treatment adherence of relapsing multiple sclerosis (RMS) patients using an electronic auto-injection device (RebiSmart®) for subc...

    Authors: Virginia A. Devonshire, Anthony Feinstein and Patrick Moriarty

    Citation: BMC Research Notes 2016 9:148

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  8. Content type: Technical Note

    The choice of an animal model for cerebrovascular research is often determined by the disease subtype to be studied (e.g. ischemic stroke, hemorrhage, trauma), as well as the nature of the intervention to be t...

    Authors: Sundeep Mangla, Jae H. Choi, Frank C. Barone, Carol Novotney, Jenny Libien, Erwin Lin and John Pile-Spellman

    Citation: BMC Research Notes 2015 8:808

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  9. Content type: Research article

    In the last decade canine models have been used extensively to study genetic causes of neurological disorders such as epilepsy and Alzheimer’s disease and unravel their pathophysiological pathways. Reverse tra...

    Authors: Quirine E. M. Stassen, Frank M. Riemers, Hannah Reijmerink, Peter A. J. Leegwater and Louis C. Penning

    Citation: BMC Research Notes 2015 8:761

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  10. Content type: Research article

    During almost one-third of our life, maturation of the nervous system promotes strength and muscle mass increase. However, as age advances, the nervous system begins to suffer a slow and continue reduction of ...

    Authors: Walter Krause Neto, Adriano Polican Ciena, Carlos Alberto Anaruma, Romeu Rodrigues de Souza and Eliane Florencio Gama

    Citation: BMC Research Notes 2015 8:713

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  11. Content type: Research article

    Caffeine is a widely used stimulant with potentially beneficial effects on cognition as well as vasoconstrictive properties. In functional magnetic imaging research, caffeine has gained attention as a potentia...

    Authors: Urs Heilbronner, Hermann Hinrichs, Hans-Jochen Heinze and Tino Zaehle

    Citation: BMC Research Notes 2015 8:520

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  12. Content type: Technical Note

    The heterogeneity of the brain requires appropriate molecular biological approaches to account for its morphological complexity. Laser-assisted microdissection followed by transcript profiling by quantitative ...

    Authors: Seico Benner, Masaki Kakeyama, Toshihiro Endo, Wataru Yoshioka and Chiharu Tohyama

    Citation: BMC Research Notes 2015 8:252

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  13. Content type: Research article

    Oxidative stress is one of the mechanisms underlying pathogenesis in neurodegenerative diseases such as Alzheimer’s disease. Generally, oxidative stress represents cell toxicity; however, we recently found tha...

    Authors: Yurina Ogura, Kazunori Sato, Ken-Ichi Kawashima, Nanako Kobayashi, Sei Imura, Kotaro Fujino, Hideo Kawaguchi and Taku Nedachi

    Citation: BMC Research Notes 2014 7:840

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  14. Content type: Research article

    Microtubule-associated protein tau (MAPT) is abundant in neurons and functions in assembly and stabilization of microtubules to maintain cytoskeletal structure. Human MAPT transcripts undergo alternative splicing...

    Authors: Seyyed Hani Moussavi Nik, Morgan Newman, Swamynathan Ganesan, Mengqi Chen, Ralph Martins, Giuseppe Verdile and Michael Lardelli

    Citation: BMC Research Notes 2014 7:767

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  15. Content type: Research article

    The nucleus accumbens (NAc) has a well established role in reward processing. Yet, there is growing evidence showing that NAc function, and its connections to other parts of the brain, is also critically invol...

    Authors: Sara E Berger, Alexis T Baria, Marwan N Baliki, Ali Mansour, Kristi M Herrmann, Souraya Torbey, Lejian Huang, Elle L Parks, Thomas J Schnizter and A Vania Apkarian

    Citation: BMC Research Notes 2014 7:739

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  16. Content type: Research article

    Gastric disturbances such as dyspepsia are routinely encountered by multiple sclerosis (MS) patients, and these conditions are often treated with gastric acid suppressors such as proton pump inhibitors, histam...

    Authors: Scott A Sands, Sheila Tsau, Thomas M Yankee, Brooks L Parker, Aaron C Ericsson and Steven M LeVine

    Citation: BMC Research Notes 2014 7:605

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  17. Content type: Short Report

    The toxicity of heme breakdown products may contribute to the pathogenesis of intracerebral hemorrhage (ICH). Heme catabolism is catalyzed by the heme oxygenase enzymes. We have previously reported that heme o...

    Authors: Jing Chen-Roetling, Ying Cai and Raymond F Regan

    Citation: BMC Research Notes 2014 7:561

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