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Pharmacology and Toxicology

  1. Content type: Case Report

    Metoclopramide is a commonly used anti-emetic drug known to cause extrapyramidal symptoms as adverse effects, amongst which are dystonic reactions. These reactions are more frequent at high doses of metoclopra...

    Authors: Frank-Leonel Tianyi, Valirie Ndip Agbor and Tsi Njim

    Citation: BMC Research Notes 2017 10:32

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  2. Content type: Research article

    Pharmacovigilance activities are in a developing stage in Nepal. ADR reporting is mainly confined to healthcare professionals working in institutions recognized as regional pharmacovigilance centers. Community...

    Authors: Nisha Jha, Devendra Singh Rathore, Pathiyil Ravi Shankar, Shital Bhandary, Rabi Bushan Pandit, Sudesh Gyawali and Mohamed Alshakka

    Citation: BMC Research Notes 2017 10:4

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  3. Content type: Research article

    We have previously reported the design, pharmacological properties and imaging application of bradykinin (BK) B2 receptor (B2R) ligands conjugated with fluorophores such as fluorescein derivatives at their N-term...

    Authors: Lajos Gera, Xavier Charest-Morin, Melissa Jean, Hélène Bachelard and François Marceau

    Citation: BMC Research Notes 2016 9:452

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  4. Content type: Case report

    Plate developer is a chemical used in the printing industry and is a corrosive alkaline agent containing sodium metasilicate as the main substance. Plate developer poisoning is rare. Literature search revealed...

    Authors: B. G. A. Rathnamali, G. Samarajiwa, D. D. K. Abeyratne, G. N. D. Perera and S. B. Gunatilake

    Citation: BMC Research Notes 2016 9:412

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  5. Content type: Research article

    Syzygium jambos has been used as a traditional medicine for the treatment of inflammatory diseases in Bangladesh. The study investigates the high performance liquid chromatography (HPL...

    Authors: Hemayet Hossain, Shaikh Emdadur Rahman, Proity Nayeeb Akbar, Tanzir Ahmed Khan, Md. Mahfuzur Rahman and Ismet Ara Jahan

    Citation: BMC Research Notes 2016 9:191

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  6. Content type: Case Report

    Tricyclic antidepressants (TCA) are becoming one of the most frequently used substances in self poisoning. Significant morbidity and mortality associated with TCA overdose are often related to and refractory h...

    Authors: Dayakshi D. K. Abeyaratne, Chathuri Liyanapathirana, Anushka Gamage, Piyumanthi Karunarathne, Medhini Botheju and Jegarajah Indrakumar

    Citation: BMC Research Notes 2016 9:167

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  7. Content type: Research article

    Previously, we validated the mouse thigh infection model to test the therapeutic equivalence of generic antibiotic products. Here, our aim was to compare the in vivo efficacy of amikacin products in clinical u...

    Authors: Andres F. Zuluaga, Carlos A. Rodriguez, Maria Agudelo and Omar Vesga

    Citation: BMC Research Notes 2015 8:546

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  8. Content type: Research article

    Medication errors (MEs) are important problems in all hospitalized populations, especially in intensive care unit (ICU). Little is known about the prevalence of medication prescribing errors in the ICU of hosp...

    Authors: Oumer Sada, Addisu Melkie and Workineh Shibeshi

    Citation: BMC Research Notes 2015 8:448

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  9. Content type: Research article

    The various parts of Cresecentia cujete have some important biological activities. In folklore medicine leaves are used to treat hematomas, tumors and hypertension. Fruit decoction is used to treat diarrhea, stom...

    Authors: Mst. Shahnaj Parvin, Nandita Das, Nusrat Jahan, Most. Afia Akhter, Laizuman Nahar and Md. Ekramul Islam

    Citation: BMC Research Notes 2015 8:412

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  10. Content type: Research article

    Mine tailings, containing metals and production chemicals such as flotation chemicals and flocculants, may pose an environmental threat to aquatic organisms living in downstream ecosystems. The aim of this wor...

    Authors: Pål A. Olsvik, Henning A. Urke, Tom O. Nilsen, John B. Ulvund and Torstein Kristensen

    Citation: BMC Research Notes 2015 8:389

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  11. Content type: Research article

    Hyperkalemia is an infrequent but potentially serious complication of low molecular weight heparin (LMWH) use. While there are a number of trials comparing LMWH to unfractionated heparin (UFH) there is no comp...

    Authors: Nima Melzer, Peter Bramlage and Hans-Christoph Michaelis

    Citation: BMC Research Notes 2014 7:880

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  12. Content type: Case Report

    Genetic factors as predictor of the individual outcome of drug therapy is one aim of personalized medicine approaches.

    Authors: Henriette E Meyer zu Schwabedissen, Werner Siegmund, Heyo K Kroemer and Jens D Rollnik

    Citation: BMC Research Notes 2014 7:688

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  13. Content type: Case Report

    Topiramate is a drug which emerged from its anticonvulsant properties and now over the years is used for a wider range of indications, including migraine prophylaxis. We described a very rare case of topiramat...

    Authors: Arjuna Medagama, Tissa Senaratne, Jayasuriya Mudiyanselage Ruwanthi Panchali Bandara, Rajitha Asanga Abeysekera and Imbulpitiya Vidanalage Buddhini Imbulpitiya

    Citation: BMC Research Notes 2014 7:665

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  14. Content type: Case Report

    The literature describing the long-term use of lithium carbonate to reinstate reduced levels of white blood cell counts in patients treated with clozapine is scarce. We describe a case of successful recommence...

    Authors: Chathurie Suraweera, Raveen Hanwella and Varuni de Silva

    Citation: BMC Research Notes 2014 7:635

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  15. Content type: Research article

    It has been reported that direct activation of the cannabinoid CB1 receptor in epidermal growth factor (EGR)-stimulated PC-3 prostate cancer cells results in an anti-proliferative effect accompanied by a down-reg...

    Authors: Mariateresa Cipriano, Sandra Gouveia-Figueira, Emma Persson, Malin Nording and Christopher J Fowler

    Citation: BMC Research Notes 2014 7:441

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  16. Content type: Short Report

    Different flavonoids are known to interfere with influenza A virus replication. Recently, we showed that the structurally similar flavonoids baicalein and biochanin A inhibit highly pathogenic avian H5N1 influ...

    Authors: Martin Michaelis, Patchima Sithisarn and Jindrich Cinatl Jr

    Citation: BMC Research Notes 2014 7:384

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