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  1. Randomised trials provide evidence that patient decision aids improve outcomes with respect to patient knowledge, involvement and satisfaction in decision making. It is less clear how these complex interventio...

    Authors: Ian Brown, Alastair Bradley, Chirk Jenn Ng, Brigitte Colwell and Nigel Mathers
    Citation: BMC Research Notes 2014 7:347
  2. Majority of mutations found to date in the BRCA1/BRCA2 genes in breast and/or ovarian cancer families are point mutations or small insertions and deletions scattered over the coding sequence and splice junctions....

    Authors: Sumadee De Silva, Kamani Hemamala Tennekoon, Eric Hamilton Karunanayake, Indrani Amarasinghe and Preethika Angunawela
    Citation: BMC Research Notes 2014 7:344
  3. Cyperus esculentus L, is a minor but important crop in Ghana. They are noted mostly by their aphrodisiac properties among others. The nuts are often eaten raw as an unprocessed snack due to its rich flavour and t...

    Authors: Patrick F Ayeh-Kumi, Patience B Tetteh-Quarcoo, Kwabena O Duedu, Akua S Obeng, Kantanka Addo-Osafo, Samuel Mortu and Richard H Asmah
    Citation: BMC Research Notes 2014 7:343
  4. The usefulness of time-limited consecutive data collection compared to continuous consecutive data collection in conditions which show seasonal variations is unclear. The objective of this study is to assess w...

    Authors: Chun Shing Kwok, Stanley D Musgrave, Gill M Price, Genevieve Dalton and Phyo Kyaw Myint
    Citation: BMC Research Notes 2014 7:342
  5. The population aged 85 + − the “oldest old” – is now the fastest growing age segment in Canada. Although existing research demonstrates high health services utilization and medication burden in this population...

    Authors: Christopher S Tsoi, Justin Y Chow, Kenny S Choi, Hiu-Wah Li, Jason X Nie, C Shawn Tracy, Li Wang and Ross EG Upshur
    Citation: BMC Research Notes 2014 7:340
  6. Changes in diet and exercise have been separately demonstrated to improve Depression, although scientific evidence available is scarce. In a previously published controlled study, just recommending these and o...

    Authors: Mauro Garcia-Toro, Margalida Gili, Olga Ibarra, Saray Monzón, Margalida Vives, Javier Garcia-Campayo, Rocío Gomez-Juanes and Miguel Roca
    Citation: BMC Research Notes 2014 7:339
  7. Health professionals in athletic training, chiropractic, osteopathy, and physiotherapy fields, require high-level knowledge and skills in their assessment and management of patients. This is important when com...

    Authors: Mark D Hecimovich, Irene Styles and Simone E Volet
    Citation: BMC Research Notes 2014 7:338
  8. Targeted therapy against the Epidermal Growth Factor Receptor (EGFR) is among the most promising molecular therapeutics for Head and Neck Squamous Cell Carcinoma (HNSCC). However, drug resistance limits the cl...

    Authors: Carolien Boeckx, Christine Weyn, Isabelle Vanden Bempt, Vanessa Deschoolmeester, An Wouters, Pol Specenier, Carl Van Laer, Danielle Van den Weyngaert, Mark Kockx, Jan B Vermorken, Marc Peeters, Patrick Pauwels, Filip Lardon and Marc Baay
    Citation: BMC Research Notes 2014 7:337
  9. Methods for objective evaluation of stress in animals are important, but clinically difficult. An alternative method to study the sympathetic activity may be to investigate Chromogranin A (CGA), Chromogranin B...

    Authors: Mats Stridsberg, Ann Pettersson, Ragnvi Hagman, Christoffer Westin and Odd Höglund
    Citation: BMC Research Notes 2014 7:336
  10. Tc-sestamibi is the most frequently used radionuclide agent for the detection of parathyroid adenomas in the clinical setting. However, Tc-tetrofosmin is another such agent that may be used for this purpose. T...

    Authors: Konstantinos Romanidis, Evangelos Karathanos, Eleni-Aikaterini Nagorni, Alexandra Giatromanolaki, Efthimios Sibridis, Athanassios Zissimopoulos, Theodosia Vogiatzaki, Constantinos Simopoulos and Michael Pitiakoudis
    Citation: BMC Research Notes 2014 7:335
  11. Sac Pox, an enzyme from the extremophilic crenarchaeal Sulfolobus acidocaldarius (Sac), was isolated by virtue of its phosphotriesterase (or paraoxonase; Pox) activity, i.e. its ability to hydrolyze the neurotoxi...

    Authors: Janek Bzdrenga, Julien Hiblot, Guillaume Gotthard, Charlotte Champion, Mikael Elias and Eric Chabriere
    Citation: BMC Research Notes 2014 7:333
  12. Among the variety of methods used to evaluate locomotor function following a spinal cord injury (SCI), the Basso Mouse Scale score (BMS) has been widely used for mice. However, the BMS mainly focuses on hindli...

    Authors: Michiko Shigyo, Norio Tanabe, Tomoharu Kuboyama, Song-Hyen Choi and Chihiro Tohda
    Citation: BMC Research Notes 2014 7:332
  13. Hemolytic uremic syndrome (HUS) is a systemic and potentially fatal complication of gastroenteritis secondary to Shiga toxin-producing enterohemorrhagic Escherichia coli (EHEC) infection characterized by microang...

    Authors: Shannon J Hostetter, Amy F Helgerson, James C Paton, Adrienne W Paton and Nancy A Cornick
    Citation: BMC Research Notes 2014 7:331
  14. Leptospirosis, a spirochaetal zoonotic disease of worldwide distribution, endemic in Europe, has been recognized as an important emerging infectious disease, though yet it is mostly a neglected disease which i...

    Authors: Adriana Calderaro, Giovanna Piccolo, Chiara Gorrini, Sara Montecchini, Mirko Buttrini, Sabina Rossi, Maddalena Piergianni, Flora De Conto, Maria Cristina Arcangeletti, Carlo Chezzi and Maria Cristina Medici
    Citation: BMC Research Notes 2014 7:330
  15. Salmonella resistant to third-generation cephalosporin has been isolated from an increasing number of animals worldwide. The purpose of this study was to examine ESBL (extended-spectrum β-lactamases)-producing an...

    Authors: Ki-Eun Lee, Seong-In Lim, Hwan-Won Choi, Suk-Kyung Lim, Jae-Young Song and Dong-Jun An
    Citation: BMC Research Notes 2014 7:329
  16. Cryptococcus neoformans is saprophytic encapsulated yeast. Infection is acquired by inhalation of the organism and could be asymptomatic or limited to the lungs, specially in the immunocompetent host. Cryptococca...

    Authors: Damith S Liyanage, Lakmini PS Pathberiya, Inuka K Gooneratne, Manjula HPC Caldera, Priyankara WS Perera and Ranjani Gamage
    Citation: BMC Research Notes 2014 7:328
  17. In the past ten years there have been three separate outbreaks of fungal contaminated steroid injections from compounding pharmacies. The 2012 outbreak of central nervous system fungal infections associated wi...

    Authors: George Nelson, Olga Fermo, Kiran Thakur, Elizabeth Felton, Jee Bang, Lucy Wilson, Susan Rhee, Rafael Llinas, Kristine Johnson and David Sullivan
    Citation: BMC Research Notes 2014 7:327
  18. The gut-derived incretin hormones, glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1, are released in response to ingestion of nutrients. Both hormones are highly insulinotropic in stric...

    Authors: Filip K Knop, Asger Lund, Sten Madsbad, Jens J Holst, Thure Krarup and Tina Vilsbøll
    Citation: BMC Research Notes 2014 7:326
  19. Microinvasive ductal carcinoma in situ of the breast is a rare entity defined as ductal carcinoma in situ with invasive foci measuring no more than 1 mm. In general, the outcome is excellent, similar to ductal...

    Authors: Cvetka Grasic Kuhar and Erika Matos
    Citation: BMC Research Notes 2014 7:325
  20. Hyperammonemic encephalopathy may occur when urease-positive bacteria in the urinary tract produce ammonium which directly enters systemic circulation. Predisposing conditions such as a neurogenic bladder can ...

    Authors: Christian Cordano, Elisabetta Traverso, Valentina Calabrò, Chiara Borzone, Silvia Stara, Roberta Marchese and Lucio Marinelli
    Citation: BMC Research Notes 2014 7:324
  21. Life-space mobility refers to the spatial area an individual moves through, the frequency and need for assistance. Based on the assumption that measurement scale properties are context-specific, we tested the ...

    Authors: Erja Portegijs, Susanne Iwarsson, Merja Rantakokko, Anne Viljanen and Taina Rantanen
    Citation: BMC Research Notes 2014 7:323
  22. Docetaxel is a key antineoplastic drug for treatment of non-small cell lung cancer. Ocular adverse events of docetaxel include epiphora (excess tearing) and conjunctivitis. Epiphora has been reported to be ass...

    Authors: Tomoko Yamagishi, Nobuaki Ochi, Hiromichi Yamane, Satoshi Hasebe and Nagio Takigawa
    Citation: BMC Research Notes 2014 7:322
  23. Olfaction plays a significant role in insect behavior during critical steps of their life-cycle, such as host-seeking during foraging or the search for a mate. Here, we explored genetic polymorphism within and...

    Authors: Audrey Arnal, Pierre Kengne, Cecile Brengues, Kounbobr Roch Dabire, Abdoulaye Diabate, Hubert Bassene and Frederic Simard
    Citation: BMC Research Notes 2014 7:321
  24. Enormous volumes of short read data from next-generation sequencing (NGS) technologies have posed new challenges to the area of genomic sequence comparison. The multiple sequence alignment approach is hardly a...

    Authors: Ngoc Hieu Tran and Xin Chen
    Citation: BMC Research Notes 2014 7:320
  25. In 2011, seven decentralized Public Health Regional Surveillance Teams (PHRSTs) were restructured into four centralized Public Health Preparedness and Response (PHP&R) regional offices to realign preparedness ...

    Authors: Catherine V Donovan, Milissa Markiewicz and Jennifer A Horney
    Citation: BMC Research Notes 2014 7:319
  26. Vincristine, a type of vinca alkaloid, is widely used in the treatment of various childhood and adult malignancies. A well-known side effect of vincristine is its neurotoxicity and it is rarely indicted in vag...

    Authors: Zarka Samoon and Munira Shabbir-Moosajee
    Citation: BMC Research Notes 2014 7:318
  27. Low-intensity pulsed ultrasound is a pain-free therapy performed daily at home by the patient and has been shown to promote fracture healing. Teriparatide is a parathyroid hormone preparation that activates os...

    Authors: Koji Nozaka, Yoichi Shimada, Naohisa Miyakoshi, Shin Yamada, Michio Hongo, Yuji Kasukawa, Hidetomo Saito and Hiroaki Kijima
    Citation: BMC Research Notes 2014 7:317
  28. Juvenile idiopathic arthritis is a relatively common chronic disease of childhood, and is associated with persistent morbidity and extra-articular complications, one of the most common being uveitis. The intro...

    Authors: Francesco La Torre, Marco Cattalini, Barbara Teruzzi, Antonella Meini, Fulvio Moramarco and Florenzo Iannone
    Citation: BMC Research Notes 2014 7:316
  29. Genomic features of whole genome sequences emerging from various sequencing and annotation projects are represented and stored in several formats. Amongst these formats, the GFF (Generic/General Feature Format...

    Authors: Achal Rastogi and Dinesh Gupta
    Citation: BMC Research Notes 2014 7:315
  30. The introduction of next generation sequencing (NGS) has revolutionized molecular diagnostics, though several challenges remain limiting the widespread adoption of NGS testing into clinical practice. One such ...

    Authors: Getiria Onsongo, Jesse Erdmann, Michael D Spears, John Chilton, Kenneth B Beckman, Adam Hauge, Sophia Yohe, Matthew Schomaker, Matthew Bower, Kevin A T Silverstein and Bharat Thyagarajan
    Citation: BMC Research Notes 2014 7:314
  31. While paraneoplastic leukocytosis is a common phenomenon in solid tumors, extreme elevations of white blood counts (WBC) in the range of more than 100,000/μl are uncommon in patients with non-hematologic malig...

    Authors: Christiane Dorn, Stefanie Bugl, Elke Malenke, Martin R Müller, Katja C Weisel, Ulrich Vogel, Marius Horger, Lothar Kanz and Hans-Georg Kopp
    Citation: BMC Research Notes 2014 7:313
  32. The barcoding of next generation sequencing libraries has become an essential part of the experimental design. Barcoding not only allows the sequencing of more than one sample per lane, but also reduces techni...

    Authors: Ethan Ford, Chrysa Nikopoulou, Antonis Kokkalis and Dimitris Thanos
    Citation: BMC Research Notes 2014 7:312
  33. Chylothorax is an extremely rare but potentially life-threatening complication after radical neck dissection. We report the case of a bilateral chylothorax after total thyroidectomy and cervico-central and cer...

    Authors: Tina Runge, Yves Borbély, Daniel Candinas and Christian Seiler
    Citation: BMC Research Notes 2014 7:311
  34. Atopic dermatitis (AD) is a multifactorial chronic inflammatory skin disease presenting with a relapsing clinical pattern similar to chronic autoimmune disease. Several human transglutaminases have been define...

    Authors: Krista Ress, Kaupo Teesalu, Triine Annus, Urve Putnik, Kristi Lepik, Katrin Luts, Oivi Uibo and Raivo Uibo
    Citation: BMC Research Notes 2014 7:310
  35. Preventing mother-to-child transmission (PMTCT) of human immunodeficiency virus infection (HIV) has been a fundamental advancement in the acquired immunodeficiency syndrome (AIDS) response for the past decade....

    Authors: Gebremedhin Derebe, Sibhatu Biadgilign, Marina Trivelli, Gemechis Hundessa, Zinash D Robi, Mikael Gebre-Mariam and Misrak Makonnen
    Citation: BMC Research Notes 2014 7:309
  36. There is increasing evidence that a strong primary care is a cornerstone of an efficient health care system. But Switzerland is facing a shortage of primary care physicians (PCPs). This pushed the Federal Coun...

    Authors: Ryan Tandjung, Catherine Ritter, Dagmar M Haller, Peter Tschudi, Mireille Schaufelberger, Thomas Bischoff, Lilli Herzig, Thomas Rosemann and Johanna Sommer
    Citation: BMC Research Notes 2014 7:308
  37. The psychological impact of dual-disasters (earthquakes and a nuclear accident), on affected communities is unknown. This study investigated the impact of a dual-disaster (earthquakes and radioactive contamina...

    Authors: Tomihisa Niitsu, Kota Takaoka, Saho Uemura, Akiko Kono, Akihiko Saito, Norito Kawakami, Michiko Nakazato and Eiji Shimizu
    Citation: BMC Research Notes 2014 7:307
  38. Acute kidney injury (AKI) is a common and a serious complication among patients admitted to intensive care units (ICUs), and has been the focus of many studies leading to recent advances in diagnosis and class...

    Authors: Eranga S Wijewickrama, Gowri M Ratnayake, Chaminda Wikramaratne, Rezvi Sheriff and Senaka Rajapakse
    Citation: BMC Research Notes 2014 7:305
  39. Gene expression analysis using quantitative reverse transcription PCR (qRT-PCR) is a robust method wherein the expression levels of target genes are normalised using internal control genes, known as reference ...

    Authors: Debashree L Ray and Joshua C Johnson
    Citation: BMC Research Notes 2014 7:304
  40. The presence of “mechanic’s hands” is one of the clinical clues for collagen vascular diseases. However, the exact relevance of “mechanic’s hands” in collagen vascular diseases has not been well documented. Th...

    Authors: Erei Sohara, Takeshi Saraya, Shinji Sato, Naoki Tsujimoto, Takayasu Watanabe, Saori Takata, Yasutaka Tanaka, Haruyuki Ishii, Hajime Takizawa and Hajime Goto
    Citation: BMC Research Notes 2014 7:303
  41. High-quality expression data are required to investigate the biological effects of microRNAs (miRNAs). The goal of this study was, first, to assess the quality of miRNA expression data based on microarray tech...

    Authors: Alain Sewer, Sylvain Gubian, Ulrike Kogel, Emilija Veljkovic, Wanjiang Han, Arnd Hengstermann, Manuel C Peitsch and Julia Hoeng
    Citation: BMC Research Notes 2014 7:302
  42. There is no validated scale to assess neurodevelopment of infants and children in Sri Lanka. The Bayley III scales have used widely globally but it has not been validated for Sri Lankan children. We administer...

    Authors: Pavithra Godamunne, Chathurika Liyanage, Nalin Wimaladharmasooriya, Arunasalem Pathmeswaran, Ananda Rajitha Wickremasinghe, Cryshelle Patterson and Nalini Sathiakumar
    Citation: BMC Research Notes 2014 7:300
  43. Adolescents are a risk group for acquiring sexually transmitted diseases, including HIV. Correct knowledge about transmission mechanisms is a prerequisite to taking appropriate precautions to avoid infection. ...

    Authors: Sophie Degroote, Dirk Vogelaers, Griet Liefhooghe, Peter Vermeir and Dominique M Vandijck
    Citation: BMC Research Notes 2014 7:299
  44. Parents of children with migraine have described a higher prevalence of sleep bruxism and other sleep disturbances in their children. The objective of this study was to use polysomnography to investigate the p...

    Authors: Alice Hatsue Masuko, Thais Rodrigues Villa, Marcia Pradella-Hallinan, Alexander Joseph Moszczynski, Deusvenir de Souza Carvalho, Sergio Tufik, Gilmar Fernandes do Prado and Fernando Morgadinho Santos Coelho
    Citation: BMC Research Notes 2014 7:298
  45. Truck driving is the second most common occupation among Canadian men. Transportation of goods via roads is of crucial importance for the Canadian economy. The industry is responsible annually for $17 billion ...

    Authors: Beatrice McDonough, Michelle Howard, Ricardo Angeles, Lisa Dolovich, Francine Marzanek-Lefebvre, John J Riva and Stephanie Laryea
    Citation: BMC Research Notes 2014 7:297

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