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  1. Porphyra yezoensis Ueda is one of the most important edible seaweed, with a dimorphic life cycle which consists of gametophyte as macroscopical blade and sporophyte as microscopic filamentous. Conspicuous differe...

    Authors: Songdong Shen, Gaochuan Zhang, Yanyan Li, Li Wang, Pu Xu and Lefei Yi

    Citation: BMC Research Notes 2011 4:428

    Content type: Short Report

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  2. The Airtraq® optical laryngoscope (Prodol Ltd., Vizcaya, Spain) is a novel disposable device facilitating tracheal intubation in routine and difficult airway patients. No data investigating routine tracheal intub...

    Authors: Gereon Schälte, Ulrike Scheid, Steffen Rex, Mark Coburn, Britta Fiedler, Rolf Rossaint and Norbert Zoremba

    Citation: BMC Research Notes 2011 4:425

    Content type: Research article

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  3. Laboratory assays are needed for early stage non-small lung cancer (NSCLC) that can link molecular and clinical heterogeneity to predict relapse after surgical resection. We technically validated two miRNA ass...

    Authors: Jesper Dahlgaard, Wiktor Mazin, Thomas Jensen, Mette Pøhl, Wiam Bshara, Anker Hansen, Eric Kanisto, Stephen Jacques Hamilton-Dutoit, Olfred Hansen, Henrik Hager, Henrik J Ditzel, Sai Yendamuri and Steen Knudsen

    Citation: BMC Research Notes 2011 4:424

    Content type: Research article

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  4. Identification of the Mycobacterium tuberculosis complex organisms to the species level is important for diagnostic, therapeutic and epidemiologic perspectives. Indeed, isolates are routinely identified as belong...

    Authors: Imen Ben Kahla, Mireille Henry, Jalel Boukadida and Michel Drancourt

    Citation: BMC Research Notes 2011 4:423

    Content type: Technical Note

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  5. Although motor deficits are gaining attention in autism research much less attention has been paid to the physical activity patterns in this group of children. The participants in this study were a group of ch...

    Authors: Megan MacDonald, Phil Esposito and Dale Ulrich

    Citation: BMC Research Notes 2011 4:422

    Content type: Short Report

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  6. To carry out a time and motion study of patients presenting at the Emergency Department (ED) by measuring waiting times at the ED dept throughout the day. The objectives were:

    Authors: Matthias Azzopardi, Marija Cauchi, Karl Cutajar, Robert Ellul, Charles Mallia-Azzopardi and Victor Grech

    Citation: BMC Research Notes 2011 4:421

    Content type: Research article

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  7. FLP recombinase mediated integration into a pre-integrated FRT site is routinely used to generate highly reproducible stable transgenic cell lines. In this study, we broaden the system of site specific integra...

    Authors: Christoph Waldner, Olga Rempel, Fabian Schütte, Mert Yanik, Natalie Solomentsew and Gerhart U Ryffel

    Citation: BMC Research Notes 2011 4:420

    Content type: Research article

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  8. The pancreas has dual functions as a digestive organ and as an endocrine organ, by secreting digestive enzymes and endocrine hormones. Some early studies have revealed that serum amylase levels are lower in in...

    Authors: Kei Nakajima, Toshitaka Muneyuki, Hiromi Munakata and Masafumi Kakei

    Citation: BMC Research Notes 2011 4:419

    Content type: Correspondence

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  9. Clinical reasoning plays a major role in the ability of doctors to make a diagnosis and reach treatment decisions. This paper describes the use of four clinical reasoning tests in the second National Medical S...

    Authors: Mitra Amini, Mohsen Moghadami, Javad Kojuri, Hamidreza Abbasi, Ali Arhami Doolat Abadi, Nezar Ali Molaee, Elham Pishbin, Hamid Reza Javadzade, Vahid Monsef Kasmaee, Hasan Vakili, Mohamad Ali Reis Sadat, Roghaye Akbari, Bita Omidvar, Afshin Shafaghi, Marzie Dehbozorgian, Mohammad Morad Jafari…

    Citation: BMC Research Notes 2011 4:418

    Content type: Research article

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  10. The increasing migration of health professionals to affluent countries is not a recent phenomenon and has been addressed in literature. However the various facets of physician migration from Pakistan, the thir...

    Authors: Nazish Imran, Zahra Azeem, Imran I Haider, Naeem Amjad and Muhammad R Bhatti

    Citation: BMC Research Notes 2011 4:417

    Content type: Research article

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  11. Most of the empirical studies that support the efficacy of prolonged exposure (PE) for treating posttraumatic stress disorder (PTSD) have been conducted on white mainstream English-speaking populations. Althou...

    Authors: Mildred Vera, María L Reyes-Rabanillo, Deborah Juarbe, Coralee Pérez-Pedrogo, Alicia Olmo, Rafael Kichic and William F Chaplin

    Citation: BMC Research Notes 2011 4:415

    Content type: Research article

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  12. For practical and financial reasons, self-reported instead of measured height and weight are often used. The aim of this study is to evaluate the validity of self-reports and to identify potential predictors o...

    Authors: Anna-Kristin Brettschneider, Angelika Schaffrath Rosario and Ute Ellert

    Citation: BMC Research Notes 2011 4:414

    Content type: Short Report

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  13. In modern life science research it is very important to have an efficient management of high throughput primary lab data. To realise such an efficient management, four main aspects have to be handled: (I) long...

    Authors: Christian Colmsee, Steffen Flemming, Matthias Klapperstück, Matthias Lange and Uwe Scholz

    Citation: BMC Research Notes 2011 4:413

    Content type: Technical Note

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  14. Hepatitis E virus (HEV) infection is a serious health problem in developing countries and is also increasingly reported in industrialized regions. HEV is considered a zoonotic agent and strains isolated from s...

    Authors: Nereida Jiménez de Oya, Ignacio de Blas, Ana-Belén Blázquez, Miguel A Martín-Acebes, Nabil Halaihel, Olivia Gironés, Juan-Carlos Saiz and Estela Escribano-Romero

    Citation: BMC Research Notes 2011 4:412

    Content type: Research article

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  15. Next generation sequencing of BACs is a viable option for deciphering the sequence of even large and highly repetitive genomes. In order to optimize this strategy, we examined the influence of read length on t...

    Authors: Stefan Taudien, Burkhard Steuernagel, Ruvini Ariyadasa, Daniela Schulte, Thomas Schmutzer, Marco Groth, Marius Felder, Andreas Petzold, Uwe Scholz, Klaus FX Mayer, Nils Stein and Matthias Platzer

    Citation: BMC Research Notes 2011 4:411

    Content type: Research article

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  16. Real-time quantitative RT-PCR (qPCR) is a powerful technique capable of accurately quantitating mRNA expression levels over a large dynamic range. This makes qPCR the most widely used method for studying quant...

    Authors: Alexandre S Stephens, Sebastien R Stephens and Nigel A Morrison

    Citation: BMC Research Notes 2011 4:410

    Content type: Technical Note

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  17. A clinical history of peptic ulcer has been reported to be associated with a high rate of ulcer recurrence in nonsteroidal anti-inflammatory drug (NSAID) users. Therefore, it is a very important issue to preci...

    Authors: Yuji Amano, Goichi Uno, Takafumi Yuki, Mayumi Okada, Yasumasa Tada, Nobuhiko Fukuba, Norihisa Ishimura, Shunji Ishihara and Yoshikazu Kinoshita

    Citation: BMC Research Notes 2011 4:409

    Content type: Research article

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  18. Follicle stimulating hormone (FSH) is an important hormone responsible for growth, maturation and function of the human reproductive system. FSH regulates the synthesis of steroid hormones such as estrogen and...

    Authors: Deepthi Telikicherla, Aditi Ambekar, Shyam Mohan Palapetta, Sutopa B Dwivedi, Rajesh Raju, Jyoti Sharma, TS Keshava Prasad, YL Ramachandra, S Sujatha Mohan, Jagadeesha Maharudraiah, Srabani Mukherjee and Akhilesh Pandey

    Citation: BMC Research Notes 2011 4:408

    Content type: Short Report

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  19. Preclinical and clinical studies have shown that salmon calcitonin has cartilage protective effects in joint degenerative diseases, such as osteoarthritis (OA). However, the presence of the calcitonin receptor...

    Authors: Toni Segovia-Silvestre, Caroline Bonnefond, Bodil C Sondergaard, Tjorbjoern Christensen, Morten A Karsdal and Anne C Bay-Jensen

    Citation: BMC Research Notes 2011 4:407

    Content type: Research article

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  20. Boswellic acids mixture of triterpenic acids obtained from the oleo gum resin of Boswellia serrata and known for its effectiveness in the treatment of chronic inflammatory disease including peritumor edema. Boswe...

    Authors: Alsaba F Raja, Furqan Ali, Inshad A Khan, Abdul S Shawl and Daljit S Arora

    Citation: BMC Research Notes 2011 4:406

    Content type: Short Report

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  21. Escherichia coli has been extensively studied as a prokaryotic model organism whose whole genome was determined in 1997. However, it is difficult to identify all the gene products involved in diverse functions by...

    Authors: Xiao Chang, Yun Li, Jie Ping, Xiao-Bin Xing, Han Sun, Peng Jia, Chuan Wang, Yuan-Yuan Li and Yi-Xue Li

    Citation: BMC Research Notes 2011 4:405

    Content type: Data Note

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  22. 454 sequencing is currently the method of choice for sequencing of antibody repertoires and libraries containing large numbers (106 to 1012) of different molecules with similar frameworks and variable regions whi...

    Authors: Ponraj Prabakaran, Emily Streaker, Weizao Chen and Dimiter S Dimitrov

    Citation: BMC Research Notes 2011 4:404

    Content type: Research article

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  23. To improve the diagnosis of tuberculosis (TB), more rapid diagnostic techniques such as antibody detection based on immunochromatographic methods were developed. The objective of this study was to evaluate the...

    Authors: Al-habib O Said Toihir, Vincent Richard, Vaomalala Raharimanga, Samuel H Andrianarisoa, Gabriel M Ranjalahy, Herimanana Ramarokoto and Voahangy Rasolofo

    Citation: BMC Research Notes 2011 4:403

    Content type: Short Report

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  24. Dupuytren's contracture is a condition of the palmar fascia involving contractures of the fascia and skin in the hand. Current treatment for Dupuytren's contracture is mainly limited to surgery. In the Netherl...

    Authors: Jetty A Overbeek, Fernie JA Penning-van Beest, Edith M Heintjes, Robert A Gerber, Joseph C Cappelleri, Steven ER Hovius and Ron MC Herings

    Citation: BMC Research Notes 2011 4:402

    Content type: Research article

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  25. Norway spruce is widely distributed across Europe and the predominant tree of the Alpine region. Fast growth and the fact that timber can be harvested cost-effectively in relatively young populations define it...

    Authors: Silvia Fluch, Agnes Burg, Dieter Kopecky, Andreas Homolka, Nadine Spiess and Giovanni G Vendramin

    Citation: BMC Research Notes 2011 4:401

    Content type: Research article

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  26. Because of its typical architecture, inheritance and small size, mitochondrial (mt) DNA is widely used for phylogenetic studies. Gene order is generally conserved in most taxa although some groups show conside...

    Authors: Gwenaelle Danic-Tchaleu, Serge Heurtebise, Benjamin Morga and Sylvie Lapègue

    Citation: BMC Research Notes 2011 4:400

    Content type: Research article

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  27. Identifying the molecular interactions using bioinformatics tools before venturing into wet lab studies saves the energy and time considerably. The present study summarizes, molecular interactions and binding ...

    Authors: Radhakrishnan Narayana Swamy, A Gnanamani, Sangeetha Shanmugasamy, Ramesh Kumar Gopal and Asit Baran Mandal

    Citation: BMC Research Notes 2011 4:399

    Content type: Research article

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  28. Although community pharmacists in the United Kingdom are expected to assess elderly patients' needs for additional support in managing their medicines, there is limited data on potentially useful assessment to...

    Authors: Solomon J Lubinga, Ian Millar and Joseph B Babigumira

    Citation: BMC Research Notes 2011 4:398

    Content type: Short Report

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  29. Na+/I- symporter (NIS)-mediated iodide uptake allows radioiodine therapy for thyroid cancer. NIS is also expressed in breast tumors, raising potential for radionuclide therapy of breast cancer. However, NIS expre...

    Authors: Sasha J Beyer, Xiaoli Zhang, Rafael E Jimenez, Mei-Ling T Lee, Andrea L Richardson, Kun Huang and Sissy M Jhiang

    Citation: BMC Research Notes 2011 4:397

    Content type: Research article

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  30. Previous studies identified CD147 as the chemotactic receptor on inflammatory leukocytes for extracellular cyclophilins (eCyp). However, CD147 is not known to associate with signal transducing molecules, so ot...

    Authors: Alexander Trachtenberg, Tatiana Pushkarsky, Shannon Heine, Stephanie Constant, Beda Brichacek and Michael Bukrinsky

    Citation: BMC Research Notes 2011 4:396

    Content type: Research article

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  31. Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine upstream of many inflammatory cytokines. MIF is implicated in several acute and chronic inflammatory conditions. MIF's promoter regio...

    Authors: Pedro L Vera and Katherine L Meyer-Siegler

    Citation: BMC Research Notes 2011 4:395

    Content type: Research article

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  32. Circular Binary Segmentation (CBS) is a permutation-based algorithm for array Comparative Genomic Hybridization (aCGH) data analysis. CBS accurately segments data by detecting change-points using a maximal-t test...

    Authors: Fang-Han Hsu, Hung-I H Chen, Mong-Hsun Tsai, Liang-Chuan Lai, Chi-Cheng Huang, Shih-Hsin Tu, Eric Y Chuang and Yidong Chen

    Citation: BMC Research Notes 2011 4:394

    Content type: Research article

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  33. Hairy root cultures produced via Agrobacterium rhizogenes-mediated transformation have emerged as practical biological models to elucidate the biosynthesis of specialized metabolites. To effectively understand th...

    Authors: Jose Condori, Cesar Nopo-Olazabal, Giuliana Medrano and Fabricio Medina-Bolivar

    Citation: BMC Research Notes 2011 4:392

    Content type: Research article

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  34. Biomarkers have been used extensively in clinical studies to assess toxicant exposure in smokers and non-smokers and have recently been used in the evaluation of novel tobacco products. The urinary metabolite ...

    Authors: Emmanuel Minet, Graham Errington, Gerhard Scherer, Kirk Newland, Mehran Sharifi, Brian Bailey, Mike McEwan and Francis Cheung

    Citation: BMC Research Notes 2011 4:391

    Content type: Short Report

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  35. Service accreditation is a structured process of recognising and promoting performance and adherence to standards. Typically, accreditation agencies either receive standards from an authorized body or develop ...

    Authors: Jeffrey Braithwaite, Johanna Westbrook, Brian Johnston, Stephen Clark, Mark Brandon, Margaret Banks, Clifford Hughes, David Greenfield, Marjorie Pawsey, Angus Corbett, Andrew Georgiou, Joanne Callen, John Øvretveit, Catherine Pope, Rosa Suñol, Charles Shaw…

    Citation: BMC Research Notes 2011 4:390

    Content type: Project Note

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  36. Visceral leishmaniasis is a notifiable parasitic disease that had increased in incidence in our region on the past few years. It is common in children. In adults, it occurs more on a background of immunodefici...

    Authors: Hazar Lahlou, Ahmed B Filali, Meryem Alami, Moncef Amrani, Rhizlane Berrady, Samira Rabhi and Wafaa Bono

    Citation: BMC Research Notes 2011 4:389

    Content type: Short Report

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  37. Local public health departments (LHDs) in the United States have been encouraged to collaborate with various other community organizations and individuals. Current research suggests that many forms of active p...

    Authors: James Studnicki, Elena A Platonova, Chris N Eiechelberger and John W Fisher

    Citation: BMC Research Notes 2011 4:387

    Content type: Research article

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  38. Social epidemiology seeks in part to understand how social factors--ideas, beliefs, attitudes, actions, and social connections--influence health. However, national health datasets have not kept up with the evo...

    Authors: Peter Muennig, Gretchen Johnson, Jibum Kim, Tom W Smith and Zohn Rosen

    Citation: BMC Research Notes 2011 4:385

    Content type: Data Note

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  39. Biological processes such as metabolic pathways, gene regulation or protein-protein interactions are often represented as graphs in systems biology. The understanding of such networks, their analysis, and thei...

    Authors: Georgios A Pavlopoulos, Sean D Hooper, Alejandro Sifrim, Reinhard Schneider and Jan Aerts

    Citation: BMC Research Notes 2011 4:384

    Content type: Technical Note

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  40. The incidence of colonic diverticular disease varies with national origin, cultural background and diet. The frequency of this disease increases with advancing age. Right-sided diverticular disease is uncommon...

    Authors: Jasim M Radhi, Jennifer A Ramsay and Odette Boutross-Tadross

    Citation: BMC Research Notes 2011 4:383

    Content type: Research article

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  41. Modern microscope platforms are able to generate multiple gigabytes of image data in a single experimental session. In a routine research laboratory workflow, these data are initially stored on the local acqui...

    Authors: Oliver Müller, Peter Lipp and Lars Kaestner

    Citation: BMC Research Notes 2011 4:382

    Content type: Technical Note

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  42. The small molecule Halofuginone (HF) is a potent regulator of extracellular matrix (ECM ) gene expression and is unique in its therapeutic potential. While the basis for HF effects is unknown, inhibition of TG...

    Authors: Yana G Kamberov, Jihoon Kim, Ralph Mazitschek, Winston P Kuo and Malcolm Whitman

    Citation: BMC Research Notes 2011 4:381

    Content type: Research article

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  43. An ongoing evaluation system is essential to determine if the academic system in place has worked to produce a better product, hence the objective of our study was to evaluate the satisfaction level among medi...

    Authors: Bushra Manzar and Nabeel Manzar

    Citation: BMC Research Notes 2011 4:380

    Content type: Short Report

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  44. HIV infection is associated with a high prevalence of antiphospholipid antibodies (aPL) and increased thrombotic events but the aetiopathogenic link between the two is unclear.

    Authors: Anthony C Becker, Elena Libhaber, Karen Sliwa, Sham Singh, Simon Stewart, Mohammed Tikly and Mohammed R Essop

    Citation: BMC Research Notes 2011 4:379

    Content type: Short Report

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  45. Hemispherical asymmetry, sex differences and age-related changes have been reported for the human brain. Meanwhile it was still unclear the presence of the asymmetry or sex differences in the human brain occur...

    Authors: Soichiro Kitamura, Masayuki Morikawa, Kuniaki Kiuchi, Toshiaki Taoka, Masami Fukusumi, Kimihiko Kichikawa and Toshifumi Kishimoto

    Citation: BMC Research Notes 2011 4:378

    Content type: Research article

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  46. Plants often release a complex blend of volatile organic compounds (VOC) in response to insect herbivore damage. Among those blends of VOC green leaf volatiles (GLV) have been demonstrated to function as defen...

    Authors: Jurgen Engelberth

    Citation: BMC Research Notes 2011 4:377

    Content type: Short Report

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