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Page 133 of 139

  1. Content type: Technical Note

    To analyze gene function in mammalian cells tetracycline inducible expression of a gene-of-interest at a specific genomic location (Flp-In T-REx™) is most attractive. However, leakiness of basal transgene expr...

    Authors: Sabine Senkel, Christoph Waldner, Gerhart U Ryffel and Heike Thomas

    Citation: BMC Research Notes 2009 2:210

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  2. Content type: Short Report

    Bovine herpesviruses type 1 (BoHV1) and type 5 (BoHV5) are two closely related pathogens of cattle. The identity of the two viruses on the amino acid level averages 82%. Despite their high antigenetic similari...

    Authors: Evgeni Gabev, Cornel Fraefel, Mathias Ackermann and Kurt Tobler

    Citation: BMC Research Notes 2009 2:209

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  3. Content type: Short Report

    There is little confidence in the consistency of estimation of DNA concentrations when samples move between laboratories. Evidence on this consistency is largely anecdotal. Therefore there is a need first to m...

    Authors: Jay Brown, Alexander N Donev, Charalampos Aslanidis, Pippa Bracegirdle, Katherine P Dixon, Manuela Foedinger, Rhian Gwilliam, Matthew Hardy, Thomas Illig, Xiayi Ke, Dagni Krinka, Camilla Lagerberg, Päivi Laiho, David H Lewis, Wendy McArdle, Simon Patton…

    Citation: BMC Research Notes 2009 2:208

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  4. Content type: Short Report

    Deschampsia antarctica shows tolerance to extreme environmental factors such as low temperature, high light intensity and an increasing UV radiation as result of the Antarctic ozone layer thinning. It is very lik...

    Authors: Jaime R Sánchez-Venegas, Alejandro Navarrete, Jorge Dinamarca, León A Bravo Ramírez, Ana Gutiérrez Moraga and Manuel Gidekel

    Citation: BMC Research Notes 2009 2:207

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  5. Content type: Technical Note

    Our SigWin-detector discovers significantly enriched windows of (genomic) elements in any sequence of values (genes or other genomic elements in a DNA sequence) in a fast and reproducible way. However, since i...

    Authors: Wim C de Leeuw, Han Rauwerda, Márcia A Inda, Oskar Bruning and Timo M Breit

    Citation: BMC Research Notes 2009 2:205

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  6. Content type: Short Report

    The reindeer lichen is the product of a mutualistic relationship between a fungus and an algae. Lichen demonstrate a remarkable capacity to tolerate dehydration. This tolerance is driven by a variety of bioche...

    Authors: Sini Junttila, Kean-Jin Lim and Stephen Rudd

    Citation: BMC Research Notes 2009 2:204

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  7. Content type: Short Report

    BMI was increased (>25) in 22% of young healthy subjects. Increased cholesterol values (>5.0 mmol/L) were found in 23% of subjects, LDL-C (>3.0 mmol/L) in 23%, triglycerides (>1.7 mmol/L) in 11% of subjects. W...

    Authors: Jadranka Sertic, Ljiljana Juricic, Hana Ljubic, Tamara Bozina, Jasna Lovric, Jasenka Markeljevic, Bojan Jelakovic, Marijan Merkler and Zeljko Reiner

    Citation: BMC Research Notes 2009 2:203

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  8. Content type: Short Report

    The availability of research platforms like the web tools of the National Center for Biotechnology Information (NCBI) has transformed the time-consuming task of identifying candidate genes from genetic studies...

    Authors: Rajani S Sadasivam, Gayathri Sundar, Laura K Vaughan, Murat M Tanik and Donna K Arnett

    Citation: BMC Research Notes 2009 2:201

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  9. Content type: Short Report

    In cancer care, a GP's work is rarely defined clearly. Our aim was to assess GPs' work with cancer patients in France and in Norway, where the roles of the GP and the organization of the system are rather diff...

    Authors: Lise Demagny, Knut Holtedahl, Janine Bachimont, Tommy Thorsen, Alain Letourmy and Martine Bungener

    Citation: BMC Research Notes 2009 2:200

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  10. Content type: Data Note

    Consolidating transcriptome data of non-human primates is essential to annotate primate genome sequences, and will facilitate research using non-human primates in the genomic era. Macaca fascicularis is a macaque...

    Authors: Naoki Osada, Makoto Hirata, Reiko Tanuma, Yutaka Suzuki, Sumio Sugano, Keiji Terao, Jun Kusuda, Yosuke Kameoka, Katsuyuki Hashimoto and Ichiro Takahashi

    Citation: BMC Research Notes 2009 2:199

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  11. Content type: Short Report

    The Copper/Zinc superoxide dismutase (Cu/ZnSOD) gene, SOD gene, was isolated from a Deschampsia antarctica Desv. by cDNA library screening. The expression of SOD gene in the leaves of D. antarctica was determined...

    Authors: Jaime R Sánchez-Venegas, Jorge Dinamarca, Ana Gutiérrez Moraga and Manuel Gidekel

    Citation: BMC Research Notes 2009 2:198

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  12. Content type: Technical Note

    Our aim was to develop an objective computerised system for measuring different types of retinal haemorrhages in differing digital images, for use as a research tool. Despite developing various fully automated...

    Authors: Tariq Aslam, Paul Chua, Matthew Richardson, Praveen Patel and Mohammed Musadiq

    Citation: BMC Research Notes 2009 2:196

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  13. Content type: Short Report

    The functional integration of the neuro-, endocrine- and immune-systems suggests that the transcriptome of white blood cells may reflect neuropsychiatric states, and be used as a non-invasive diagnostic indica...

    Authors: Johan H van Heerden, Ana Conesa, Dan J Stein, David Montaner, Vivienne Russell and Nicola Illing

    Citation: BMC Research Notes 2009 2:195

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  14. Content type: Short Report

    Succinate dehydrogenase (SDH) and fumarate hydratase (FH) are tricarboxylic acid (TCA) cycle enzymes that are also known to act as tumour suppressor genes. Increased succinate or fumarate levels as a consequen...

    Authors: Katie T Huang, Alexander Dobrovic and Stephen B Fox

    Citation: BMC Research Notes 2009 2:194

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  15. Content type: Short Report

    Mitochondria (mt) contain their own autonomously replicating DNA, constituted as a small circular genome encoding essential subunits of the respiratory chain. Mt DNA is characterized by a genetic code which di...

    Authors: Joachim EM Jacob, Bartel Vanholme, Thomas Van Leeuwen and Godelieve Gheysen

    Citation: BMC Research Notes 2009 2:192

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  16. Content type: Short Report

    Bub1 is a component of the spindle assembly checkpoint, a surveillance mechanism that maintains chromosome stability during M-phase. Bub1 is essential during the early stages of embryogenesis, with homozygous BUB...

    Authors: Valerie Tilston, Stephen S Taylor and David Perera

    Citation: BMC Research Notes 2009 2:190

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  17. Content type: Short Report

    Saffron (Crocus sativus) is considered the world's most expensive spice. Used mainly as a colorant for foodstuffs, it is highly appreciated for its aromatic and flavouring properties. Since no molecular markers f...

    Authors: Angela Rubio-Moraga, Raquel Castillo-López, Lourdes Gómez-Gómez and Oussama Ahrazem

    Citation: BMC Research Notes 2009 2:189

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  18. Content type: Short Report

    The cultivated strawberry Fragaria ×ananassa is one of the most economically-important soft-fruit species. Few structural genomic resources have been reported for Fragaria and there exists an urgent need for the ...

    Authors: Julio Bonet, Elena Lopez Girona, Daniel J Sargent, Monica C Muñoz-Torres, Amparo Monfort, Albert G Abbott, Pere Arús, David W Simpson and Jahn Davik

    Citation: BMC Research Notes 2009 2:188

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  19. Content type: Short Report

    The rK39 strip test is reported to be simple, sensitive, specific, non-invasive and economical test. Since this method is supposed to be patient friendly, it may easily be accepted for sero-epidemiological sur...

    Authors: Dharmendra P Singh, Shyam Sundar and Tribhuban M Mohapatra

    Citation: BMC Research Notes 2009 2:187

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  20. Content type: Short Report

    Post caesarean wound infection is not only a leading cause of prolonged hospital stay but a major cause of the widespread aversion to caesarean delivery in developing countries. In order to control and prevent...

    Authors: Oliver C Ezechi, Asuquo Edet, Hakim Akinlade, Chidinma V Gab-Okafor and Ebiere Herbertson

    Citation: BMC Research Notes 2009 2:186

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  21. Content type: Technical Note

    Though the biological process of aphid feeding is well documented, no one to date has sought to apply it as a tool to screen the biological responses to chemicals and drugs, in ecotoxicology, genotoxicology an...

    Authors: Aviv Dombrovsky, Terence Neil Ledger, Gilbert Engler and Alain Robichon

    Citation: BMC Research Notes 2009 2:185

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  22. Content type: Short Report

    In eusocial hymenopteran insects, foraging genes, members of the cGMP-dependent protein kinase family, are considered to contribute to division of labor through behavioral caste differentiation. However, the rela...

    Authors: Yosuke Kodaira, Hajime Ohtsuki, Jun Yokoyama and Masakado Kawata

    Citation: BMC Research Notes 2009 2:184

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  23. Content type: Short Report

    Comparative genome mapping determines the linkage between homologous genes of related taxa. It has already been used in plants to characterize agronomically important genes in lesser studied species, using inf...

    Authors: Jean-Marc Celton, David Chagné, Stuart D Tustin, Shingo Terakami, Chikako Nishitani, Toshiya Yamamoto and Susan E Gardiner

    Citation: BMC Research Notes 2009 2:182

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  24. Content type: Short Report

    The transmissible spongiform encephalopathies (TSEs) comprise a group of fatal degenerative neurological diseases in humans and other mammals. After infection, the cellular prion protein isoform PrPC is converted...

    Authors: Michael J Taheny, Nerik Izkhakov, Alexander A Vostrov and Wolfgang W Quitschke

    Citation: BMC Research Notes 2009 2:178

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  25. Content type: Correspondence

    Fragile × syndrome is caused by loss of expression of the FMRP protein involved in the control of a large number of mRNA targets. The Drosophila ortholog dFXR interacts with a protein complex that includes Arg...

    Authors: Charlotte Madsen, Karen Grønskov, Karen Brøndum-Nielsen and Thomas G Jensen

    Citation: BMC Research Notes 2009 2:177

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  26. Content type: Short Report

    Discrete RNA structures such as cis-acting replication elements (cre) in the coding region of RNA virus genomes create characteristic suppression of synonymous site variability (SSSV). Different phylogenetic meth...

    Authors: Matías Victoria, Rodney Colina, Marize Pereira Miagostovich, José P Leite and Juan Cristina

    Citation: BMC Research Notes 2009 2:176

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  27. Content type: Short Report

    Zbtb7A is a proto-oncogenic transcriptional regulator that plays an important role in adipogenesis, osteogenesis and oncogenesis, but little is known about the regulation of Zbtb7A gene expression which is of ...

    Authors: Xuyu Zu, Lingling Yu, Qinsheng Sun, Feng Liu, Jue Wang, Zhenhua Xie, Ying Wang, Wei Xu and Yuyang Jiang

    Citation: BMC Research Notes 2009 2:175

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  28. Content type: Short Report

    Neuro-imaging studies demonstrate plasticity of cortical gray matter before and after practice for some motor and cognitive tasks in adults. Other imaging studies show functional changes after practice, but th...

    Authors: Richard J Haier, Sherif Karama, Leonard Leyba and Rex E Jung

    Citation: BMC Research Notes 2009 2:174

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  29. Content type: Short Report

    Although the Jamaica road traffic act mandates motorcycle riders to wear approved helmets, opponents suggest that the local road conditions obviate any benefits from helmet use that have been proven in Develop...

    Authors: Ivor W Crandon, Hyacinth E Harding, Shamir O Cawich, Morton AC Frankson, Georgiana Gordon-Strachan, Noel McLennon, Archibald H McDonald, Doreen Fearon-Boothe, Nicole Meeks-Aitken, Karen Watson-Jones and Kenneth C James

    Citation: BMC Research Notes 2009 2:172

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  30. Content type: Short Report

    Guillain-Barré Syndrome (GBS), the leading cause of acute flaccid paralysis worldwide, is an autoimmune disorder involving the loss of the myelin sheaths encasing peripheral nerve axons, leading to a loss of n...

    Authors: Laura Nelson, Robert Gormley, Mark S Riddle, David R Tribble and Chad K Porter

    Citation: BMC Research Notes 2009 2:171

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  31. Content type: Short Report

    Recent studies investigating off-line processes of consolidation in motor learning have demonstrated a sudden, short-lived improvement in performance after 5–30 minutes of post-training inactivity. Here, we in...

    Authors: Remy Schmitz, Manuel Schabus, Fabien Perrin, André Luxen, Pierre Maquet and Philippe Peigneux

    Citation: BMC Research Notes 2009 2:170

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  32. Content type: Short Report

    Identifying the endogenous RNA induced silencing complex(RISC)-associated RNAs is essential for understanding the cellular regulatory networks by miRNAs. Recently, isolation of RISC-associated mRNAs using anti...

    Authors: Yukinobu Hayashida, Takahiro Nishibu, Kunio Inoue and Tsutomu Kurokawa

    Citation: BMC Research Notes 2009 2:169

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  33. Content type: Technical Note

    Viruses and small-genome bacteria (~2 megabases and smaller) comprise a considerable population in the biosphere and are of interest to many researchers. These genomes are now sequenced at an unprecedented rat...

    Authors: Padmanabhan Mahadevan, John F King and Donald Seto

    Citation: BMC Research Notes 2009 2:168

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  34. Content type: Short Report

    The expression of vaccine antigens in lactic acid bacteria (LAB) is a safe and cost-effective alternative to traditional expression systems. In this study, we investigated i) the expression of Human papillomav...

    Authors: Naima G Cortes-Perez, Pascale Kharrat, Philippe Langella and Luis G Bermúdez-Humarán

    Citation: BMC Research Notes 2009 2:167

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  35. Content type: Short Report

    Haemophilus influenzae requires a porphyrin source for aerobic growth and possesses multiple mechanisms to obtain this essential nutrient. This porphyrin requirement may be satisfied by either heme alone, or prot...

    Authors: Daniel J Morton, Thomas W Seale, Timothy M VanWagoner, Paul W Whitby and Terrence L Stull

    Citation: BMC Research Notes 2009 2:166

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  36. Content type: Short Report

    It was hypothesised that colorectal cancer (CRC) could be diagnosed in biopsies by measuring the combined expression of a small set of well known genes. Genes were chosen based on their role in either the brea...

    Authors: Caroline A Kerr, Robert Dunne, Barney M Hines, Michelle Zucker, Leah Cosgrove, Andrew Ruszkiewicz, Trevor Lockett and Richard Head

    Citation: BMC Research Notes 2009 2:164

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  37. Content type: Short Report

    Venturia inaequalis is an economically-important disease of apple causing annual epidemics of scab worldwide. The pathogen is a heterothallic ascomycete with an annual cycle of sexual reproduction on infected app...

    Authors: Xiangming Xu, Tony Roberts, Dez Barbara, Nick G Harvey, Liqiang Gao and Daniel J Sargent

    Citation: BMC Research Notes 2009 2:163

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  38. Content type: Short Report

    In view of the role of TLR2 activation in host defense against mycobacteria, the present study was conducted to examine whether TLR2 polymorphisms could account for the increased prevalence of tuberculosis in ...

    Authors: Debasis Biswas, Shailendra K Gupta, Girish Sindhwani and Abhishek Patras

    Citation: BMC Research Notes 2009 2:162

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