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  1. Most approaches used to find recurrent or differential DNA Copy Number Alterations (CNA) in array Comparative Genomic Hybridization (aCGH) data from groups of tumour samples depend on the discretization of the...

    Authors: Jorma J de Ronde, Christiaan Klijn, Arno Velds, Henne Holstege, Marcel JT Reinders, Jos Jonkers and Lodewyk FA Wessels

    Citation: BMC Research Notes 2010 3:298

    Content type: Research article

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  2. In a recent study, two-dimensional (2D) network layouts were used to visualize and quantitatively analyze the relationship between chronic renal diseases and regulated genes. The results revealed complex relat...

    Authors: Suresh K Bhavnani, Arunkumaar Ganesan, Theodore Hall, Eric Maslowski, Felix Eichinger, Sebastian Martini, Paul Saxman, Gowtham Bellala and Matthias Kretzler

    Citation: BMC Research Notes 2010 3:296

    Content type: Short Report

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  3. Many species of marine shrimp in the Family Penaeidae, viz. Penaeus (Litopenaeus) vannamei, Penaeus monodon, Penaeus (Fenneropenaeus) chinensis, and Penaeus (Marsupenaeus) japonicus, are animals of economic impor...

    Authors: Pimlapas Leekitcharoenphon, Udon Taweemuang, Prasit Palittapongarnpim, Rattanawadee Kotewong, Thararat Supasiri and Burachai Sonthayanon

    Citation: BMC Research Notes 2010 3:295

    Content type: Short Report

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  4. The translocation or shuttling of proteins between the nucleus and cytoplasm (nucleocytoplasmic transport [NCPT]) is often a rapid event following stimulation with growth factors or in response to stress or ot...

    Authors: Keiko Suzuki, Pinaki Bose, Rebecca YY Leong-Quong, Donald J Fujita and Karl Riabowol

    Citation: BMC Research Notes 2010 3:294

    Content type: Short Report

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  5. Glioblastomas (GBM), the most frequent malignant brain tumors in adults, are characterized by an aggressive local growth pattern and highly invasive tumor cells. This invasion is facilitated by expression of m...

    Authors: Carsten Hagemann, Jelena Anacker, Stefanie Haas, Daniela Riesner, Beate Schömig, Ralf-Ingo Ernestus and Giles H Vince

    Citation: BMC Research Notes 2010 3:293

    Content type: Short Report

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  6. The G allele of the CD45 77C/G SNP (rs17612648), which has previously been suggested to be associated with autoimmune disorders, was genotyped in 446 Swedish myasthenia gravis (MG) patients and 2303 matched co...

    Authors: Ryan Ramanujam, Ritva Pirskanen and Lennart Hammarström

    Citation: BMC Research Notes 2010 3:292

    Content type: Research article

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  7. Assessment of DNA profile quality is vital in forensic DNA analysis, both in order to determine the evidentiary value of DNA results and to compare the performance of different DNA analysis protocols. Generall...

    Authors: Johannes Hedman, Ricky Ansell and Anders Nordgaard

    Citation: BMC Research Notes 2010 3:290

    Content type: Research article

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  8. The application of computational modeling to rationally design drugs and characterize macro biomolecular receptors has proven increasingly useful due to the accessibility of computing clusters and clouds. Auto...

    Authors: Casey W Bullock, Reed B Jacob, Owen M McDougal, Greg Hampikian and Tim Andersen

    Citation: BMC Research Notes 2010 3:289

    Content type: Research article

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  9. Vampire bat related rabies harms both livestock industry and public health sector in central Brazil. The geographical distributions of vampire bat-transmitted rabies virus variants are delimited by mountain ch...

    Authors: Shinji Hirano, Takuya Itou, Adolorata AB Carvalho, Fumio H Ito and Takeo Sakai

    Citation: BMC Research Notes 2010 3:288

    Content type: Short Report

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  10. Breast cancer is uncommon in young women and induces more aggressive biologic characteristics. Survival in young women has been widely studied in developed countries. Less favorable prognosis and low survival ...

    Authors: Halima Abahssain, Issam Lalya, Fatima zahra EL M'Rabet, Nabil Ismaili, Rachid Razine, Mohammed Adnane Tazi, Hind M'rabti, Omar El Mesbahi, Nourddine Benjaafar, Redouane Abouqal and Hassan Errihani

    Citation: BMC Research Notes 2010 3:286

    Content type: Short Report

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  11. Femoral access is a fundamental element of catheter-based cerebral angiography. Knowledge of location of the common femoral artery (CFA) bifurcation is important as the risk of retroperitoneal bleeding is incr...

    Authors: Alexandra R Paul, Geoffrey P Colby, Martin G Radvany, Judy Huang, Rafael J Tamargo and Alexander L Coon

    Citation: BMC Research Notes 2010 3:285

    Content type: Short Report

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  12. Several systematic reviews (SRs) have assessed the effectiveness of moxibustion for a range of conditions, often with contradictory conclusions. Our aim was to provide a critical evaluation and summary of thes...

    Authors: Myeong Soo Lee, Jung Won Kang and Edzard Ernst

    Citation: BMC Research Notes 2010 3:284

    Content type: Research article

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  13. Group A Streptococcus (GAS) is a Gram-positive human pathogen that is capable of causing a wide spectrum of human disease. Thus, the organism has evolved to colonize a number of physiologically distinct host site...

    Authors: Amity L Roberts, Robert C Holder and Sean D Reid

    Citation: BMC Research Notes 2010 3:281

    Content type: Short Report

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  14. Despite a recent increase in activities to promote evidence-based practice (EBP), it was unclear how Malaysian hospital practitioners received this new approach in medicine. This study examines their confidenc...

    Authors: Nai Ming Lai, Cheong Lieng Teng and Ming Lee Lee

    Citation: BMC Research Notes 2010 3:279

    Content type: Short Report

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  15. The staphylococci are one of the most common environmental isolates found in clean room facility. Consequently, isolation followed by comprehensive and accurate identification is an essential step in any envir...

    Authors: Norhan S Sheraba, Aymen S Yassin and Magdy A Amin

    Citation: BMC Research Notes 2010 3:278

    Content type: Data Note

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  16. The increasing number of methodologies and tools currently available to analyse gene expression microarray data can be confusing for non specialist users.

    Authors: Nicolas Servant, Eleonore Gravier, Pierre Gestraud, Cecile Laurent, Caroline Paccard, Anne Biton, Isabel Brito, Jonas Mandel, Bernard Asselain, Emmanuel Barillot and Philippe Hupé

    Citation: BMC Research Notes 2010 3:277

    Content type: Technical Note

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  17. Rating scale items in a 6-week clinical trial of olanzapine versus placebo augmentation in patients with mixed bipolar disorder partially nonresponsive to ≥14 days of divalproex monotherapy were analyzed to ch...

    Authors: John P Houston, Jennifer L Gatz, Elisabeth K Degenhardt and Hassan H Jamal

    Citation: BMC Research Notes 2010 3:276

    Content type: Short Report

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  18. The efficiency of gene therapy experiments is frequently evaluated by measuring the impact of the treatment on the expression of genes of interest by quantitative real time PCR (qRT-PCR) and by normalizing the...

    Authors: María Moreno-Igoa, Raquel Manzano, Sara Oliván, Ana C Calvo, Janne M Toivonen and Rosario Osta

    Citation: BMC Research Notes 2010 3:275

    Content type: Technical Note

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  19. We report an attempt to extend the previously successful approach of combining SNP (single nucleotide polymorphism) microarrays and DNA pooling (SNP-MaP) employing high-density microarrays. Whereas earlier stu...

    Authors: Alexandra Schosser, Katrina Pirlo, Darya Gaysina, Sarah Cohen-Woods, Leonard C Schalkwyk, Amanda Elkin, Ania Korszun, Cerisse Gunasinghe, Joanna Gray, Lisa Jones, Emma Meaburn, Anne E Farmer, Ian W Craig and Peter McGuffin

    Citation: BMC Research Notes 2010 3:274

    Content type: Technical Note

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  20. A sensitive and analytically specific nucleic acid amplification test (NAAT) is valuable in confirming the diagnosis of early Lyme disease at the stage of spirochetemia.

    Authors: Sin Hang Lee, Veronica S Vigliotti, Jessica S Vigliotti, William Jones, Jessie Williams and Jay Walshon

    Citation: BMC Research Notes 2010 3:273

    Content type: Short Report

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  21. Occupational health has received limited research attention in the Southern African Development Community (SADC). Much of the published data in this region come from South Africa and little has been reported n...

    Authors: Adamson S Muula, Emmanuel Rudatsikira and Seter Siziya

    Citation: BMC Research Notes 2010 3:272

    Content type: Short Report

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  22. Variola virus (VARV) the causative agent of smallpox, eradicated in 1980, have wide spectrum of immunomodulatory proteins to evade host immunity. Recently additional biological activity was discovered for VARV...

    Authors: Denis V Antonets, Tatyana S Nepomnyashchikh and Sergei N Shchelkunov

    Citation: BMC Research Notes 2010 3:271

    Content type: Short Report

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  23. We aim to propose interactions between the parathyroid hormone-2 receptor (PTH2R) and its ligand the tuberoinfundibular peptide of 39 residues (TIP39) by constructing a homology model of their complex. The two...

    Authors: Mirna Abraham-Nordling, Bengt Persson and Erik Nordling

    Citation: BMC Research Notes 2010 3:270

    Content type: Short Report

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  24. Cognitive tests have been used in population surveys as first stage screens for dementia but are biased by education. However functional ability scales are less biased by education than the cognitive scale and...

    Authors: S Umayal, M Kulathunga, S Somaratne, S Srikanth, S Kathriarachchi and Ranil De Silva

    Citation: BMC Research Notes 2010 3:268

    Content type: Correspondence

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  25. Structural equation modeling (SEM) is a set of statistical techniques used to measure and analyze the relationships of observed and latent variables. Similar but more powerful than regression analyses, it exam...

    Authors: Tanya N Beran and Claudio Violato

    Citation: BMC Research Notes 2010 3:267

    Content type: Technical Note

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  26. Landmark based geometric morphometrics (GM) allows the quantitative comparison of organismal shapes. When applied to systematics, it is able to score shape changes which often are undetectable by traditional m...

    Authors: Jean-Pierre AL Dujardin, Dramane Kaba and Amy B Henry

    Citation: BMC Research Notes 2010 3:266

    Content type: Short Report

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  27. Abdominal pain of unknown origin affects up to 20% of school-aged children. Evaluation of children is symptom-based without clear guidelines to investigate molecular mechanisms of abdominal pain. Aberrant mole...

    Authors: Tara J Taylor, Nader N Youssef, Ravi Shankar, David E Kleiner and Wendy A Henderson

    Citation: BMC Research Notes 2010 3:265

    Content type: Research article

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  28. A recent study reported that gene expression profiles from peripheral blood samples of healthy subjects prior to viral inoculation were indistinguishable from profiles of subjects who received viral challenge ...

    Authors: Alexander Statnikov, Nikita I Lytkin, Lauren McVoy, Jörn-Hendrik Weitkamp and Constantin F Aliferis

    Citation: BMC Research Notes 2010 3:264

    Content type: Short Report

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  29. In the psychiatric acute and emergency services patients present in severe crisis often complicated by behavioral problems, substance use, and multiple axis 1 diagnoses. In these clinical settings both legal a...

    Authors: John C Fløvig, Arne E Vaaler and Gunnar Morken

    Citation: BMC Research Notes 2010 3:263

    Content type: Research article

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  30. Expressed Sequence Tags (ESTs) are in general used to gain a first insight into gene activities from a species of interest. Subsequently, and typically based on a combination of EST and genome sequences, micro...

    Authors: Kolja Henckel, Helge Küster, Leonhard J Stutz and Alexander Goesmann

    Citation: BMC Research Notes 2010 3:262

    Content type: Technical Note

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  31. Haemoglobin (Hb) and pantophysin (Pan I) markers have been used intensively in population studies of Atlantic cod (Gadus morhua) and in the analysis of traits such as temperature tolerance, growth characteristics...

    Authors: Tudor Borza, Brent Higgins, Gary Simpson and Sharen Bowman

    Citation: BMC Research Notes 2010 3:261

    Content type: Short Report

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  32. Detection of bacterial nucleic acids in synovial fluid following total joint arthroplasty with suspected infection can be difficult; among other technical challenges, inhibitors in the specimens require extens...

    Authors: Sandeep Kathju, Roger S Lasken, Latha Satish, Sandra Johnson, Paul Stoodley, J Christopher Post and Garth D Ehrlich

    Citation: BMC Research Notes 2010 3:259

    Content type: Short Report

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  33. In 1988, the SPILI project was established in order to evaluate the cardiovascular disease (CVD) risk profile of the inhabitants of Spili, in rural Crete, Greece. The first reports from this project revealed t...

    Authors: Christos Lionis, Dimitrios Anyfantakis, Emmanouil K Symvoulakis, Sue Shea, Demosthenes Panagiotakos and Elias Castanas

    Citation: BMC Research Notes 2010 3:258

    Content type: Hypothesis

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  34. Relatively recently, the software KB™ Basecaller has replaced phred for identifying the bases from raw sequence data in DNA sequencing employing dideoxy chemistry. We have measured quantitatively the consequences...

    Authors: Richard W Hyman, Hui Jiang, Marilyn Fukushima and Ronald W Davis

    Citation: BMC Research Notes 2010 3:257

    Content type: Research article

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  35. Following disasters, separated and unaccompanied children are among the most vulnerable, therefore international organisations have formed guidelines regarding the management of these children. Guidelines incl...

    Authors: Farnaz Bazeghi and Hamid R Baradaran

    Citation: BMC Research Notes 2010 3:256

    Content type: Short Report

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  36. The coordinated activity of different flavonoid biosynthesis genes in Arabidopsis thaliana results in tissue-specific accumulation of flavonols, anthocyanins and proanthocyanidins (PAs). These compounds possess d...

    Authors: Christiane Katja Kleindt, Ralf Stracke, Frank Mehrtens and Bernd Weisshaar

    Citation: BMC Research Notes 2010 3:255

    Content type: Short Report

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  37. There is little published on current Saudi diabetic patients' practices when they are exposed to foot disorders such as open wound, ulcer, and skin cracks. These factors are usually influenced by local culture...

    Authors: Balkees A Bakhotmah and Hasan A Alzahrani

    Citation: BMC Research Notes 2010 3:254

    Content type: Short Report

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  38. Transgenic labels that allow the visualization of specific populations of neurons have proven to be powerful tools for research. Further developing such resources to label additional cell types and specific or...

    Authors: Robert W Burgess and Peter G Fuerst

    Citation: BMC Research Notes 2010 3:253

    Content type: Short Report

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  39. The CHD7 (Chromodomain Helicase DNA binding protein 7) gene encodes a member of the chromodomain family of ATP-dependent chromatin remodeling enzymes. Mutations in the CHD7 gene are found in individuals with CHAR...

    Authors: Christian Colin, Flávia S Tobaruella, Ricardo G Correa, Mari C Sogayar and Marcos A Demasi

    Citation: BMC Research Notes 2010 3:252

    Content type: Short Report

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  40. Mycobacterium avium subsp. paratuberculosis (MAP) is the etiological agent of paratuberculosis (Johne's disease) in ruminants and is suggested to be one of the etiologic factors in Crohn's disease in humans. Cont...

    Authors: Monika Dzieciol, Patrick Volgger, Johannes Khol, Walter Baumgartner, Martin Wagner and Ingeborg Hein

    Citation: BMC Research Notes 2010 3:251

    Content type: Short Report

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  41. The application of mobile computing and communication technology is rapidly expanding in the fields of health care and public health. This systematic review will summarise the evidence for the effectiveness of...

    Authors: Caroline Free, Gemma Phillips, Lambert Felix, Leandro Galli, Vikram Patel and Philip Edwards

    Citation: BMC Research Notes 2010 3:250

    Content type: Project Note

    Published on:

  42. The synergy between tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection on perceived stigma is not well studied. The objective of this study was to assess the effect of TB/HIV co-infection on...

    Authors: Amare Deribew, Yohannes HaileMichael, Markos Tesfaye, Dejene Desalegn, Ajeme Wogi and Shallo Daba

    Citation: BMC Research Notes 2010 3:249

    Content type: Short Report

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  43. Aedes aegypti is the principal vector of dengue and yellow fever viruses. The availability of the sequenced and annotated genome enables genome-wide analyses of gene expression in this mosquito. The large amount ...

    Authors: Sumudu N Dissanayake, Jose MC Ribeiro, Mei-Hui Wang, William A Dunn, Guiyun Yan, Anthony A James and Osvaldo Marinotti

    Citation: BMC Research Notes 2010 3:248

    Content type: Data Note

    Published on:

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