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  1. α-Santalol, an active component of sandalwood oil, has shown chemopreventive effects on skin cancer in different murine models. However, effects of α-santalol on cell cycle have not been studied. Thus, the obj...

    Authors: Xiaoying Zhang, Wei Chen, Ruth Guillermo, Gudiseva Chandrasekher, Radhey S Kaushik, Alan Young, Hesham Fahmy and Chandradhar Dwivedi

    Citation: BMC Research Notes 2010 3:220

    Content type: Research article

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  2. Anthroposophic medicine is a physician-provided complementary therapy system involving counselling, artistic and physical therapies, and special medications. The purpose of this analysis was to identify predic...

    Authors: Harald J Hamre, Claudia M Witt, Gunver S Kienle, Anja Glockmann, Stefan N Willich and Helmut Kiene

    Citation: BMC Research Notes 2010 3:218

    Content type: Research article

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  3. Although altruism is a key principle in our current organ donation and transplantation system, the meanings and implications of the term have been widely debated. Recently, a new type of living organ donation-...

    Authors: Marie-Chantal Fortin, Marianne Dion-Labrie, Marie-Josée Hébert and Hubert Doucet

    Citation: BMC Research Notes 2010 3:216

    Content type: Short Report

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  4. Clock family genes encode transcription factors that regulate clock-controlled genes and thus regulate many physiological mechanisms/processes in a circadian fashion. Clock1 duplicates and copies of Clock3 and...

    Authors: Marion I Paibomesai, Hooman K Moghadam, Moira M Ferguson and Roy G Danzmann

    Citation: BMC Research Notes 2010 3:215

    Content type: Research article

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  5. SNP (Single Nucleotide Polymorphism) discovery is now routinely performed using high-throughput sequencing of reduced representation libraries. Our objective was to adapt 454 GS FLX based sequencing methodolog...

    Authors: Sophie Leroux, Katia Feve, Florence Vignoles, Olivier Bouchez, Christophe Klopp, Céline Noirot, David Gourichon, Sabine Richard, Christine Leterrier, Catherine Beaumont, Francis Minvielle, Alain Vignal and Frédérique Pitel

    Citation: BMC Research Notes 2010 3:214

    Content type: Technical Note

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  6. The methylenetetrahydrofolate reductase (MTHFR) gene variant C677T has been implicated as a genetic risk factor in migraine susceptibility, particularly in Migraine with Aura. Migraine, with and without aura (...

    Authors: Annie Liu, Saraswathy Menon, Natalie J Colson, Sharon Quinlan, Hannah Cox, Madelyn Peterson, Thomas Tiang, Larisa M Haupt, Rod A Lea and Lyn R Griffiths

    Citation: BMC Research Notes 2010 3:213

    Content type: Short Report

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  7. Southern China is a major area for endemic nasopharyngeal carcinoma (NPC). Genetic factors as well as environmental factors play a role in development of NPC. To investigate the roles of previously described c...

    Authors: Xiuchan Guo, Yi Zeng, Hong Deng, Jian Liao, Yuming Zheng, Ji Li, Bailey Kessing and Stephen J O'Brien

    Citation: BMC Research Notes 2010 3:212

    Content type: Research article

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  8. The isolation of DNA-free RNA is a crucial step in the reverse transcription PCR (RT-PCR). Every RNA extraction procedure results in RNA samples contaminated with genomic DNA, which can cause false-positive ou...

    Authors: Lydia V Rump, Benedicta Asamoah and Narjol Gonzalez-Escalona

    Citation: BMC Research Notes 2010 3:211

    Content type: Technical Note

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  9. Epithelial cells are exposed to a variety of mechanical stimuli. Epithelial Na+ channels (ENaC) mediate sodium transport across apical membranes of epithelial cells that line the distal nephron, airway and alveol...

    Authors: Alexey V Karpushev, Daria V Ilatovskaya and Alexander Staruschenko

    Citation: BMC Research Notes 2010 3:210

    Content type: Short Report

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  10. Counselling on the danger signs of unpredictable obstetric complications and the appropriate management of such complications are crucial in reducing maternal mortality. The objectives of this study were to id...

    Authors: Malabika Sarker, Gerhard Schmid, Elin Larsson, Sylvia Kirenga, Manuela De Allegri, Florian Neuhann, Theodora Mbunda, Isaack Lekule and Olaf Müller

    Citation: BMC Research Notes 2010 3:209

    Content type: Short Report

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  11. Many studies have been done to find out the molecular mechanism of systemic acquired resistance (SAR) in plants in the past several decades. Numbers of researches have been carried out in the model plants such...

    Authors: Jiyu Zhang, Xiaoli Du, Qingju Wang, Xiukong Chen, Dong Lv, Kuanyong Xu, Shenchun Qu and Zhen Zhang

    Citation: BMC Research Notes 2010 3:208

    Content type: Short Report

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  12. The aim of this study was to evaluate the safety and efficacy of outpatient laparoscopic cholecystectomy (OLC) in a day surgery unit in a teaching hospital. OLC was offered to patients with symptomatic choleli...

    Authors: Athanasios Marinis, Emmanouil Stamatakis, Athanasia Tsaroucha, Nikolaos Dafnios, Georgios Anastasopoulos, Georgios Polymeneas and Theodosios Theodosopoulos

    Citation: BMC Research Notes 2010 3:207

    Content type: Short Report

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  13. Long-term acute care hospitals (LTACs) provide specialized care for patients recovering from severe acute illness. In order to facilitate research into LTAC utilization and outcomes, we studied whether or not ...

    Authors: Jeremy M Kahn and Theodore J Iwashyna

    Citation: BMC Research Notes 2010 3:205

    Content type: Short Report

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  14. The anabolic steroid, dehydroepiandosterone sulfate (DHEA-S), is secreted from the adrenal cortex. It plays a significant role in the body as a precursor to sex steroids as well as a lesser known role in the h...

    Authors: Courtney A Whetzel and Laura C Klein

    Citation: BMC Research Notes 2010 3:204

    Content type: Short Report

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  15. General transcription factor (TFII-I) is a multi-functional transcription factor encoded by the Gtf2i gene, that has been demonstrated to regulate transcription of genes critical for development. Because of th...

    Authors: Iwona Fijalkowska, Deva Sharma, Carol J Bult and Sonye K Danoff

    Citation: BMC Research Notes 2010 3:203

    Content type: Short Report

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  16. Propofol is a commonly used intravenous anesthetic agent, which produce rapid induction of and recovery from general anesthesia. Numerous clinical studies reported that propofol can potentially cause amnesia a...

    Authors: Srivatsan Kidambi, Joel Yarmush, Yevgeny Berdichevsky, Sangeetha Kamath, Wayne Fong and Joseph SchianodiCola

    Citation: BMC Research Notes 2010 3:201

    Content type: Short Report

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  17. Accurate prognosis is vital to the initiation of advance care planning particularly in a vulnerable, at risk population such as care home residents. The aim of this paper is to report on the revision and simpl...

    Authors: Davina Porock, Debra Parker-Oliver, Gregory F Petroski and Marilyn Rantz

    Citation: BMC Research Notes 2010 3:200

    Content type: Research article

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  18. The advancements in DNA sequencing technologies have allowed researchers to progress from the analyses of a single organism towards the deep sequencing of a sample of organisms. With sufficient sequencing dept...

    Authors: Kelvin Li, Eli Venter, Shibu Yooseph, Timothy B Stockwell, Lance D Eckerle, Mark R Denison, David J Spiro and Barbara A Methé

    Citation: BMC Research Notes 2010 3:199

    Content type: Technical Note

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  19. Chronic obstructive pulmonary disease (COPD) and asthma are considered underdiagnosed and misdiagnosed chronic diseases. In The Netherlands, a COPD-asthma telemedicine service has been developed to increase GP...

    Authors: Ioanna G Tsiligianni, Thys van der Molen, Nikolaos E Tzanakis, Nikolaos M Siafakas, Ellen van Heijst and Christos Lionis

    Citation: BMC Research Notes 2010 3:198

    Content type: Project Note

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  20. Apoptosis is a highly ordered and orchestrated multiphase process controlled by the numerous cellular and extra-cellular signals, which executes the programmed cell death via release of cytochrome c alterations i...

    Authors: Katarzyna Kokoszyńska, Leszek Rychlewski and Lucjan S Wyrwicz

    Citation: BMC Research Notes 2010 3:197

    Content type: Short Report

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  21. About 130 million people are infected with the hepatitis C virus (HCV) worldwide, but effective treatment options are not yet available. One of the most promising targets for antiviral therapy is nonstructural...

    Authors: Paola JS Provazzi, Helen A Arcuri, Isabel Maria VG de Carvalho-Mello, João Renato R Pinho, Maurício L Nogueira, Mário S Palma and Paula Rahal

    Citation: BMC Research Notes 2010 3:196

    Content type: Short Report

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  22. The variability of maternal serum biochemical markers for Down syndrome, free β-hCG and PAPP-A can have a different impact on false-positive rates between the 10+0 and 13+6 week of gestation. The study populat...

    Authors: Dubravka Tišlarić-Medenjak, Ivana Zec, Ana-Maria Šimundić, Senka Sabolović-Rudman, Milan Kos and Željka Bukovec Megla

    Citation: BMC Research Notes 2010 3:194

    Content type: Short Report

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  23. Routine rapid testing for Bovine Spongiform Encephalopathy (BSE) has highlighted some problems with BSE rapid test performance, the most significant being the number of initially reactive samples and the false...

    Authors: Daniela Meloni, Katia Varello, Marzia Pezzolato, Elsa Manzardo, Maria C Cavarretta, Francesco Ingravalle, Maria Caramelli and Elena Bozzetta

    Citation: BMC Research Notes 2010 3:193

    Content type: Short Report

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  24. A complete gene-expression microarray should preferably detect all genomic sequences that can be expressed as RNA in an organism, i.e. the transcriptome. However, our knowledge of a transcriptome of any organi...

    Authors: Han Rauwerda, Mark de Jong, Wim C de Leeuw, Herman P Spaink and Timo M Breit

    Citation: BMC Research Notes 2010 3:192

    Content type: Technical Note

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  25. Numerous models, of variable quality, exist to impart the complex skills required to perform vascular anastomosis. These models differ with regard to the kinds of materials used, as well as their sizes, the ti...

    Authors: Philipe N Khalil, Axel Kleespies, Markus Rentsch, Wolfgang E Thasler, Karl-Walter Jauch and Christiane J Bruns

    Citation: BMC Research Notes 2010 3:189

    Content type: Short Report

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  26. Trauma is a major health problem in the United Arab Emirates (UAE) as well as worldwide. Trauma registries provide large longitudinal databases for analysis and policy improvement. We aim in this paper to repo...

    Authors: Sami Shaban, Hani O Eid, Ezedin Barka and Fikri M Abu-Zidan

    Citation: BMC Research Notes 2010 3:187

    Content type: Short Report

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  27. The presence of a mass in the nose and paranasal sinuses may seem to be a simple problem; however it raises many questions about the differential diagnosis. The aim of this study is to evaluate the clinico-pat...

    Authors: Aminu Bakari, Olushola A Afolabi, Adeyi A Adoga, Aliyu M Kodiya and Babagana M Ahmad

    Citation: BMC Research Notes 2010 3:186

    Content type: Data Note

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  28. Polymerase chain reaction (PCR) remains a simple, flexible, and inexpensive method for enriching genomic regions of interest for next-generation sequencing. In order to utilize PCR in this context, a major cha...

    Authors: Andrew MK Brown, Ken Sin Lo, Paul Guelpa, Mélissa Beaudoin, John D Rioux, Jean-Claude Tardif, Michael S Phillips and Guillaume Lettre

    Citation: BMC Research Notes 2010 3:185

    Content type: Technical Note

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  29. Epithelial-stromal interaction provides regulatory signals that maintain correct histoarchitecture and homeostasis in the normal breast and facilitates tumor progression in breast cancer. However, research on ...

    Authors: Saevar Ingthorsson, Valgardur Sigurdsson, Agla JR Fridriksdottir, Jon G Jonasson, Jens Kjartansson, Magnus K Magnusson and Thorarinn Gudjonsson

    Citation: BMC Research Notes 2010 3:184

    Content type: Research article

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  30. The data produced by an Illumina flow cell with all eight lanes occupied, produces well over a terabyte worth of images with gigabytes of reads following sequence alignment. The ability to translate such reads...

    Authors: Parsa Hosseini, Arianne Tremblay, Benjamin F Matthews and Nadim W Alkharouf

    Citation: BMC Research Notes 2010 3:183

    Content type: Technical Note

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  31. The iris as a unique identifier is predicated on the assumption that the iris image does not alter. This does not consider the fact that the iris changes in response to certain external factors including medic...

    Authors: Deborah M Rankin, Bryan W Scotney, Philip J Morrow, Douglas R McDowell and Barbara K Pierscionek

    Citation: BMC Research Notes 2010 3:182

    Content type: Short Report

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  32. Reducing the incidence of Low birth weight (LBW) neonates by at least one third between 2000 and 2010 is one of the major goals of the United Nations resolution "A World Fit for Children". This was a case-cont...

    Authors: Elhassan M Elhassan, Ameer O Abbaker, Abderahuim D Haggaz, Magid S Abubaker and Ishag Adam

    Citation: BMC Research Notes 2010 3:181

    Content type: Short Report

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  33. A number of health benefits including improvements in acid/base balance, bone metabolism, and cardiovascular risk factors have been attributed to the intake of magnesium rich alkaline mineral water. This study...

    Authors: Richard O Day, Winston Liauw, Lynette MR Tozer, Patrick McElduff, Russell J Beckett and Kenneth M Williams

    Citation: BMC Research Notes 2010 3:180

    Content type: Short Report

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  34. The Multiplex Ligation-dependent Probe Amplification (MLPA) is widely used for analysis of copy number variations (CNVs) in single or multiple loci. MLPA is a versatile methodology and important tool in cancer...

    Authors: Kristina Pedersen, Emilia Wiechec, Bo E Madsen, Jens Overgaard and Lise Lotte Hansen

    Citation: BMC Research Notes 2010 3:179

    Content type: Technical Note

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  35. Stable isotope probing (SIP) technique was developed to link function, structure and activity of microbial cultures metabolizing carbon and nitrogen containing substrates to synthesize their biomass. Currently...

    Authors: Ingo Fetzer, Nico Jehmlich, Carsten Vogt, Hans-Hermann Richnow, Jana Seifert, Hauke Harms, Martin von Bergen and Frank Schmidt

    Citation: BMC Research Notes 2010 3:178

    Content type: Correspondence

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  36. Health campaigns are frequently covered by printed media, but coverage is not homogeneous across different types of newspapers. Switzerland as a multilinguistic country with many newspapers offers a good field...

    Authors: Carine F Wang-Buholzer, Marta Lomazzi and Bettina Borisch

    Citation: BMC Research Notes 2010 3:177

    Content type: Short Report

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  37. The prescribing of psychotropic medicines for the paediatric population is rapidly increasing. In attempts to curb the use of psychotropic medicine in the paediatric population, regulatory authorities have iss...

    Authors: Lise Aagaard and Ebba H Hansen

    Citation: BMC Research Notes 2010 3:176

    Content type: Short Report

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  38. Ontology development is a rapidly growing area of research, especially in the life sciences domain. To promote collaboration and interoperability between different projects, the OBO Foundry principles require ...

    Authors: Zuoshuang Xiang, Mélanie Courtot, Ryan R Brinkman, Alan Ruttenberg and Yongqun He

    Citation: BMC Research Notes 2010 3:175

    Content type: Technical Note

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  39. The display of N-glycan carbohydrate structures is an essential part of glycoinformatics. Several tools exist for building such structures graphically, by selecting from a palette of symbols or sugar names, or el...

    Authors: Andrew G McDonald, Keith F Tipton, Corné JM Stroop and Gavin P Davey

    Citation: BMC Research Notes 2010 3:173

    Content type: Technical Note

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  40. The practical and methodological challenges inherent in online behaviour change studies are both novel and complex. We relate our experiences of estimating and managing information technology (IT) research and...

    Authors: Jim McCambridge, Orla O'Donnell, Christine Godfrey, Zarnie Khadjesari, Stuart Linke, Elizabeth Murray and Paul Wallace

    Citation: BMC Research Notes 2010 3:172

    Content type: Short Report

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  41. The development of new microarray technologies makes custom long oligonucleotide arrays affordable for many experimental applications, notably gene expression analyses. Reliable results depend on probe design ...

    Authors: Frédérique Bidard, Sandrine Imbeaud, Nancie Reymond, Olivier Lespinet, Philippe Silar, Corinne Clavé, Hervé Delacroix, Véronique Berteaux-Lecellier and Robert Debuchy

    Citation: BMC Research Notes 2010 3:171

    Content type: Technical Note

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  42. Diabetic subjects, especially women, show high prevalence of asymptomatic bacteriuria (ASB). The aim of the present study was to evaluate the prevalence of ASB in subjects with type 2 diabetes mellitus (T2D) w...

    Authors: Athanasia Papazafiropoulou, Ioannis Daniil, Alexios Sotiropoulos, Eleni Balampani, Anthi Kokolaki, Stavros Bousboulas, Stavroula Konstantopoulou, Eystathios Skliros, Dimitra Petropoulou and Stavros Pappas

    Citation: BMC Research Notes 2010 3:169

    Content type: Short Report

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