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  1. Content type: Short Report

    Pancreatic duodenal homeobox-1 (Pdx-1) or Pdx-1-VP16 gene transfer has been shown to induce in vitro rat liver-stem WB cell conversion into pancreatic endocrine precursor cells. High glucose conditions were neces...

    Authors: Juliette Cuvelier Delisle, Lionel Martignat, Laurence Dubreil, Pierre Saï, Jean-Marie Bach, Vanessa Louzier and Steffi Bösch

    Citation: BMC Research Notes 2009 2:3

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  2. Content type: Short Report

    As the hepatitis B genotyping is important for assessing its clinical implications and geographical distribution, the sub-genotypes have been found useful for determination of specific genomic markers related ...

    Authors: Saeeda Baig, Anwar Siddiqui, Runu Chakravarty and Tariq Moatter

    Citation: BMC Research Notes 2009 2:1

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  3. Content type: Short Report

    Peroxisome proliferator-activated receptor γ coactivator 1α (PPARGC1A) is a coactivator with a vital and central role in fat and energy metabolism. It is considered to be a candidate gene for meat quality in pigs...

    Authors: Tim Erkens, Karel Bilek, Alex Van Zeveren and Luc J Peelman

    Citation: BMC Research Notes 2008 1:138

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  4. Content type: Short Report

    The human GLB1 gene is known to give rise to two alternatively spliced mRNAs, which encode two different proteins: lysosomal β-galactosidase (β-gal) and elastin-binding protein (EBP). The β-gal transcript include...

    Authors: Raül Santamaria, Lluïsa Vilageliu and Daniel Grinberg

    Citation: BMC Research Notes 2008 1:137

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  5. Content type: Short Report

    Liver-to-pancreas conversion offers new possibilities for β-cell engineering for type 1 diabetes therapy. Among conceivable sources of liver cells, we focused on BMEL cells. These untransformed mouse embryonic...

    Authors: Juliette Cuvelier Delisle, Lionel Martignat, Jean-Marie Bach, Steffi Bösch and Vanessa Louzier

    Citation: BMC Research Notes 2008 1:136

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  6. Content type: Short Report

    Adynamia in fibromyalgia (FM) may be an expression of a functional deficit of the hypothalamic-pituitary-adrenal axis and be associated with below-normal levels of urinary cortisol. Our aim was to demonstrate ...

    Authors: Silvia Izquierdo–Álvarez, Julia Pilar Bocos–Terraz, Jose Luis Bancalero–Flores, Lenin Pavón–Romero, Enrique Serrano–Ostariz and Cayetano Alegre de Miquel

    Citation: BMC Research Notes 2008 1:134

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  7. Content type: Technical Note

    We sought to describe the integrity of human genomic DNA extracted from saliva saturated cotton spit wads stored at -20°C for approximately 11 years. 783 spit wad samples were collected from an ADHD sample pop...

    Authors: Erik A Ehli, Timea Lengyel-Nelson, James J Hudziak and Gareth E Davies

    Citation: BMC Research Notes 2008 1:133

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  8. Content type: Short Report

    Plant cell cultures have been shown as feasible systems for the production of secondary metabolites, being the elicitation with biotic or abiotic stimuli the most efficient strategy to increase the production ...

    Authors: Diego Lijavetzky, Lorena Almagro, Sarai Belchi-Navarro, José M Martínez-Zapater, Roque Bru and Maria A Pedreño

    Citation: BMC Research Notes 2008 1:132

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  9. Content type: Short Report

    Mass spectrometric analysis of peptides is an essential part of protein identification and characterization, the latter meaning the identification of modifications and amino acid substitutions. There are two m...

    Authors: Harald Barsnes, Svein-Ole Mikalsen and Ingvar Eidhammer

    Citation: BMC Research Notes 2008 1:130

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  10. Content type: Project Note

    Medicago truncatula is a model species for legumes. Its functional genomics have been considerably boosted in recent years due to initiatives based both in Europe and US. Collections of mutants are becoming incre...

    Authors: Andrea Porceddu, Francesco Panara, Ornella Calderini, Lorna Molinari, Paola Taviani, Luisa Lanfaloni, Carla Scotti, Maria Carelli, Laura Scaramelli, Gianluca Bruschi, Viviane Cosson, Pascal Ratet, Henri de Larembergue, Gerard Duc, Efisio Piano and Sergio Arcioni

    Citation: BMC Research Notes 2008 1:129

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  11. Content type: Short Report

    Individuals who are aware of the risk of infection and perceive themselves to be at risk of infection are more likely to take action to prevent HIV infection. The aim of this study was to assess the knowledge ...

    Authors: Seter Siziya, Adamson S Muula and Emmanuel Rudatsikira

    Citation: BMC Research Notes 2008 1:123

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  12. Content type: Short Report

    Actinobacillus pleuropneumoniae, the causative bacterial agent of porcine pleuropneumonia, produces Apx toxins which belong to RTX toxin family and are recognized as the major virulence factors. So far, their tar...

    Authors: Philippe GAC Vanden Bergh, Laurent LM Zecchinon, Thomas Fett and Daniel Desmecht

    Citation: BMC Research Notes 2008 1:121

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  13. Content type: Short Report

    The purpose of this study was to examine whether prior outpatient antibiotic use is associated with increased 30-day mortality, after adjusting for potential confounders, for those subsequently hospitalized wi...

    Authors: Eric M Mortensen, Marcos I Restrepo, Jacqueline A Pugh and Antonio Anzueto

    Citation: BMC Research Notes 2008 1:120

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  14. Content type: Short Report

    The mocha mouse carries a spontaneous deletion in the Ap3d1 gene, encoding the delta 1 subunit of the adaptor related protein complex 3, (Ap3d1), and subsequently lack the expression of functional AP-3. This lead...

    Authors: Kim Ryun Drasbek, Mai Marie Holm, Marion Delenclos and Kimmo Jensen

    Citation: BMC Research Notes 2008 1:119

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  15. Content type: Short Report

    Symbiotic relationships between intracellular bacteria and eukaryotes are widespread in nature. Genome sequencing of the bacterial partner has provided a number of key insights into the basis of these symbiose...

    Authors: Gaku Tokuda, Nathan Lo, Aya Takase, Akinori Yamada, Yoshinobu Hayashi and Hirofumi Watanabe

    Citation: BMC Research Notes 2008 1:118

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  16. Content type: Short Report

    Access to health professionals is a key UK NHS priority, and meeting access targets is rewarded through the new General Medical Services (GMS) contract in the UK. We sought to determine the current state of ap...

    Authors: Andrea Edwards and Richard D Neal

    Citation: BMC Research Notes 2008 1:117

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  17. Content type: Short Report

    Oral squamous cell carcinoma (OSCC) is a frequent neoplasm, which is usually aggressive and has unpredictable biological behavior and unfavorable prognosis. The comprehension of the molecular basis of this var...

    Authors: Patricia Severino, Adriana M Alvares, Pedro Michaluart Jr, Oswaldo K Okamoto, Fabio D Nunes, Carlos A Moreira-Filho and Eloiza H Tajara

    Citation: BMC Research Notes 2008 1:113

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  18. Content type: Short Report

    Pneumococcal hand contamination in Indigenous children in remote communities is common (37%). It is not clear whether this requires frequent inoculation, or if pneumococci will survive on hands for long period...

    Authors: Heidi Smith-Vaughan, Faith Crichton, Jemima Beissbarth, Peter S Morris and Amanda J Leach

    Citation: BMC Research Notes 2008 1:112

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  19. Content type: Short Report

    Mammalian spermatozoa become fully motile and fertile during transit through the luminal fluid of the epididymis. At least 200 proteins are present in the epididymal lumen, but the potential roles of these lum...

    Authors: J Liu, JY Li, HY Wang, CL Zhang, N Li, YQ Lin, J Liu and WT Wang

    Citation: BMC Research Notes 2008 1:111

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  20. Content type: Short Report

    The recent determination of the complete nucleotide sequence of several Mycobacterium tuberculosis (MTB) genomes allows the use of comparative genomics as a tool for dissecting the nature and consequence of genet...

    Authors: Andrés Cubillos-Ruiz, Juan Morales and María Mercedes Zambrano

    Citation: BMC Research Notes 2008 1:110

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  21. Content type: Short Report

    More than two thirds of the highly expressed ribosomal protein (RP) genes in Saccharomyces cerevisiae contain introns, which is in sharp contrast to the genome-wide five percent intron-containing genes. It is wel...

    Authors: Jing Zhang, Martin Vingron and Stefan Roepcke

    Citation: BMC Research Notes 2008 1:109

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  22. Content type: Technical Note

    We present swps3, a vectorized implementation of the Smith-Waterman local alignment algorithm optimized for both the Cell/BE and ×86 architectures. The paper describes swps3 and compares its performances with ...

    Authors: Adam Szalkowski, Christian Ledergerber, Philipp Krähenbühl and Christophe Dessimoz

    Citation: BMC Research Notes 2008 1:107

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  23. Content type: Short Report

    Hepatocellular carcinoma (HCC) is a preventable disease rather than a curable one, since there is no well-documented effective treatment modality until now, making the molecular study of this disease mandatory.

    Authors: Abdel-Rahman N Zekri, Mohamed M Hafez, Abeer A Bahnassy, Zeinab K Hassan, Tarek Mansour, Mahmoud M Kamal and Hussein M Khaled

    Citation: BMC Research Notes 2008 1:106

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  24. Content type: Short Report

    Few Canadian studies have examined stress in residency and none have included a large sample of resident physicians. Previous studies have also not examined well-being resources nor found significant concerns ...

    Authors: Jordan S Cohen, Yvette Leung, Meriah Fahey, Linda Hoyt, Roona Sinha, Lisa Cailler, Kevin Ramchandar, John Martin and Scott Patten

    Citation: BMC Research Notes 2008 1:105

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  25. Content type: Short Report

    Bartonellosis due to Bartonella bacilliformis is a highly lethal endemic and sometimes epidemic infectious disease in South America, and a serious public health concern in Perú. There is limited information on th...

    Authors: Beronica Infante, Sandra Villar, Sandra Palma, Jenny Merello, Roberto Valencia, Luis Torres, Jamie Cok, Palmira Ventosilla, Ciro Manguiña, Humberto Guerra and Cesar Henriquez

    Citation: BMC Research Notes 2008 1:103

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  26. Content type: Short Report

    This paper reports the outcome of gefitinib for Chinese advanced NSCLC patients with poor performance status (PS) at the Peking Union Medical College Hospital.

    Authors: Zhong Wei, Wang Mengzhao, Zhang Li, Li Longyun and Zhang Xiaotong

    Citation: BMC Research Notes 2008 1:102

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  27. Content type: Short Report

    Depression is common among diabetic subjects. We conducted the present study to estimate the prevalence of depression in subjects with type 2 diabetes (T2D) in Greece.

    Authors: Alexios Sotiropoulos, Athanasia Papazafiropoulou, Ourania Apostolou, Anthi Kokolaki, Aristofanis Gikas and Stavros Pappas

    Citation: BMC Research Notes 2008 1:101

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  28. Content type: Short Report

    Little is known about the physiological role of the EBER1 and 2 nuclear RNAs during Epstein Barr viral infection. The EBERs are transcribed by cellular RNA Polymerase III and their strong expression results in 10

    Authors: Sebastian Eilebrecht, François-Xavier Pellay, Peter Odenwälder, Guillaume Brysbaert, Bernd-Joachim Benecke and Arndt Benecke

    Citation: BMC Research Notes 2008 1:100

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  29. Content type: Short Report

    Prions, the infectious agents that cause transmissible spongiform encephalopathies (TSEs), are relatively resistant to destruction by physical, enzymatic, and chemical treatments. Hydrolysis in boiling saturat...

    Authors: Justin J Greenlee, Eric M Nicholson, Amir N Hamir, Gary P Noyes, Mark T Holtzapple and Marcus E Kehrli Jr

    Citation: BMC Research Notes 2008 1:99

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  30. Content type: Short Report

    Echocardiography is a non-invasive, relatively cheap and useful imaging technique for the evaluation of cardiac diseases. The procedure has reliable levels of accuracy.

    Authors: Okechukwu S Ogah, Gail D Adegbite, Rufus O Akinyemi, Julius O Adesina, Albert A Alabi, Oscar I Udofia, Roseline F Ogundipe and Julius KL Osinfade

    Citation: BMC Research Notes 2008 1:98

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  31. Content type: Short Report

    SH-SY5Y cells exhibit a neuronal phenotype when treated with all-trans retinoic acid (RA), but the molecular mechanism of activation in the signalling pathway mediated by phosphatidylinositol 3-kinase (PI3K) i...

    Authors: Yuichiro Nishida, Naoki Adati, Ritsuko Ozawa, Aasami Maeda, Yoshiyuki Sakaki and Tadayuki Takeda

    Citation: BMC Research Notes 2008 1:95

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  32. Content type: Short Report

    Molecular studies of Bacillus diversity in various environments have been reported. However, there have been few investigations concerning Bacillus in steel plant environments. In this study, genotypic and phenot...

    Authors: Dulcecleide B Freitas, Mariana P Reis, Cláudia I Lima-Bittencourt, Patrícia S Costa, Paulo S Assis, Edmar Chartone-Souza and Andréa MA Nascimento

    Citation: BMC Research Notes 2008 1:92

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