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  1. In the last 20 years, researchers have been using computer self-administered questionnaires to gather data on a wide range of adolescent health related behaviours. More recently, researchers collecting data in...

    Authors: Simon J Denny, Taciano L Milfont, Jennifer Utter, Elizabeth M Robinson, Shanthi N Ameratunga, Sally N Merry, Theresa M Fleming and Peter D Watson

    Citation: BMC Research Notes 2008 1:52

    Content type: Short Report

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  2. Though prediction of protein secondary structures has been an active research issue in bioinformatics for quite a few years and many approaches have been proposed, a new challenge emerges as the sizes of conte...

    Authors: Darby Tien-Hao Chang, Yu-Yen Ou, Hao-Geng Hung, Meng-Han Yang, Chien-Yu Chen and Yen-Jen Oyang

    Citation: BMC Research Notes 2008 1:51

    Content type: Technical Note

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  3. The H/ACA family of small nucleolar RNAs (snoRNAs) plays a central role in guiding the pseudouridylation of ribosomal RNA (rRNA). In an effort to systematically identify the complete set of rRNA-modifying H/AC...

    Authors: Eva Freyhult, Sverker Edvardsson, Ivica Tamas, Vincent Moulton and Anthony M Poole

    Citation: BMC Research Notes 2008 1:49

    Content type: Technical Note

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  4. The introduction of PSA testing in Austria led to a steep increase of the incidence of prostate cancer. We want to present the course of the number of newly diagnosed cases of prostate cancer in Austria since ...

    Authors: Gerald Haidinger, Stephan Madersbacher, Georg Schatzl and Christian Vutuc

    Citation: BMC Research Notes 2008 1:48

    Content type: Short Report

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  5. Extensive sequencing efforts have been taking place for the Atlantic cod (Gadus morhua) in recent years, the number of ESTs in the Genbank has reached more than 140.000. Despite its importance in North Atlantic f...

    Authors: Pål A Olsvik, Liv Søfteland and Kai K Lie

    Citation: BMC Research Notes 2008 1:47

    Content type: Short Report

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    The Erratum to this article has been published in BMC Research Notes 2011 4:456

  6. Patients with HIV and hepatitis C virus (HCV) coinfection are at increased risk of developing hepatic steatosis. The aims of this study were to assess the prevalence of steatosis in a cohort with HIV-HCV coinf...

    Authors: Sumita Verma, Robert D Goldin and Janice Main

    Citation: BMC Research Notes 2008 1:46

    Content type: Short Report

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  7. Successful microarray experimentation requires a complex interplay between the slide chemistry, the printing pins, the nucleic acid probes and targets, and the hybridization milieu. Optimization of these param...

    Authors: Richard JD Rouse, Katrine Field, Jennifer Lapira, Allen Lee, Ivan Wick, Colleen Eckhardt, C Ramana Bhasker, Laura Soverchia and Gary Hardiman

    Citation: BMC Research Notes 2008 1:45

    Content type: Technical Note

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  8. We have analysed the distribution of post mortem DNA damage derived miscoding lesions from the datasets of seven published Neandertal specimens that have extensive cloned sequence coverage over the mitochondrial ...

    Authors: Sergi Vives, M Thomas Gilbert, Conchita Arenas, Elena Gigli, Oscar Lao and Carles Lalueza-Fox

    Citation: BMC Research Notes 2008 1:40

    Content type: Short Report

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  9. Acupuncture is commonly used to treat chronic sinusitis, though there is little documentation on the effect. This study presents the health-related quality of life (HRQoL) outcomes in a trial comparing traditi...

    Authors: Knut Stavem, Edna Røssberg and Pål G Larsson

    Citation: BMC Research Notes 2008 1:37

    Content type: Short Report

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  10. Electron micrographs of bacteriophage T7 reveal a tail shorter than needed to reach host cytoplasm during infection-initiating injection of a T7 DNA molecule through the tail and cell envelope. However, recent...

    Authors: Philip Serwer, Elena T Wright, Kevin W Hakala and Susan T Weintraub

    Citation: BMC Research Notes 2008 1:36

    Content type: Short Report

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  11. The aim of this study was to evaluate a simple diagnostic test for Gilbert's syndrome (GS), which avoids hospitalization and exposure to toxic test substrates. GS is the most frequent cause of isolated unconju...

    Authors: Niels Teich, Inken Lehmann, Jonas Rosendahl, Michael Tröltzsch, Joachim Mössner and Ingolf Schiefke

    Citation: BMC Research Notes 2008 1:35

    Content type: Short Report

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  12. Classical and atypical bovine spongiform encephalopathies (BSEs) are cattle prion diseases. Distinct bovine prion gene (PRNP) alleles have been associated with classical and atypical BSE susceptibility. However, ...

    Authors: Michael L Clawson, Michael P Heaton, John W Keele, Timothy PL Smith, Gregory P Harhay, Juergen A Richt and William W Laegreid

    Citation: BMC Research Notes 2008 1:32

    Content type: Technical Note

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  13. The Swine Leukocyte Antigen (SLA) system encodes molecules for self-nonself discrimination and is associated with immune responses and disease resistance. Three lines of pigs defined by their SLA-DRB1 alleles ...

    Authors: Maria I Nino-Soto, Razi Jafari Jozani, Byram Bridle and Bonnie A Mallard

    Citation: BMC Research Notes 2008 1:31

    Content type: Short Report

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  14. We have created a software implementation of a published and verified method for assigning probabilities to potential phosphorylation sites on peptides using mass spectrometric data. Our tool, named PhosCalc, ...

    Authors: Daniel MacLean, Michael A Burrell, David J Studholme and Alexandra ME Jones

    Citation: BMC Research Notes 2008 1:30

    Content type: Technical Note

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  15. During pregnancy the mammary epithelium undergoes a complex developmental process which culminates in the generation of the milk-secreting epithelium. Secretory epithelial cells display lactogenic differentiat...

    Authors: Richard Jäger, Leontios Pappas and Hubert Schorle

    Citation: BMC Research Notes 2008 1:29

    Content type: Short Report

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  16. Vigna radiata, which is classified in the family Fabaceae, is an important economic crop and a dietary staple in many developing countries. The species radiata can be further subdivided into varieties of which th...

    Authors: Noelle A Barkley, Ming L Wang, Athey G Gillaspie, Rob E Dean, Gary A Pederson and Tracie M Jenkins

    Citation: BMC Research Notes 2008 1:28

    Content type: Short Report

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  17. Cervical cancer is increasing at 1.5% per year in Ireland with 50% mortality giving 2.2% of all cancer deaths. In the Mid-West region a pilot screening programme has begun to screen all women 25–60 years. 66% ...

    Authors: Catherine O'Connor, Helena Myles, Mortimer B O'Connor, Josephine Clancy, Ailis Ryan, Mary Traynor, Dolores McGrath and Kitty O'Sullivan

    Citation: BMC Research Notes 2008 1:24

    Content type: Short Report

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  18. Less than half of U.S. hospitals meet guidelines for prompt treatment of ST-segment elevation myocardial infarction (STEMI). The Door-to-Balloon (D2B) Alliance is a collaborative effort of more than 900 hospit...

    Authors: Elizabeth H Bradley, Brahmajee K Nallamothu, Amy F Stern, Jason R Byrd, Emily J Cherlin, Yongfei Wang, Christina Yuan, Ingrid Nembhard, John E Brush Jr and Harlan M Krumholz

    Citation: BMC Research Notes 2008 1:23

    Content type: Short Report

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  19. An accurate gene expression quantification using TaqMan Arrays (TA) could be limited by the low RNA quantity obtained from some clinical samples. The novel cDNA preamplification system, the TaqMan PreAmp Maste...

    Authors: Lourdes Mengual, Moisès Burset, Mercedes Marín-Aguilera, María José Ribal and Antonio Alcaraz

    Citation: BMC Research Notes 2008 1:21

    Content type: Technical Note

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  20. Alzheimer's disease (AD) is a progressive, neurodegenerative disease mostly affecting the basal forebrain, cortex and hippocampus whereas the cerebellum is relatively spared. The reason behind this region-spec...

    Authors: Sachin Patil, Deebika Balu, Joseph Melrose and Christina Chan

    Citation: BMC Research Notes 2008 1:20

    Content type: Short Report

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  21. Recently, Schulz and colleagues have contributed to the ongoing controversy on the unproven role of oxidative stress in the aging process in their well-performed study 'Glucose restriction extends Caenorhabditis ...

    Authors: Markus Ralser and Ivor J Benjamin

    Citation: BMC Research Notes 2008 1:19

    Content type: Correspondence

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  22. Variance-stabilizing techniques have been used for some time in the analysis of gene expression microarray data. A new adaptation, the variance-stabilizing transformation (VST), has recently been developed to ...

    Authors: Mark J Dunning, Matthew E Ritchie, Nuno L Barbosa-Morais, Simon Tavaré and Andy G Lynch

    Citation: BMC Research Notes 2008 1:18

    Content type: Short Report

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  23. The use of methods, both sensitive and specific, for rabies diagnosis are important tools for the control and prophylaxis of the disease. Reverse-Transcriptase Polymerase Chain Reaction (RT-PCR) has been used ...

    Authors: Danielle B Araújo, Helio Langoni, Marilene F Almeida and Jane Megid

    Citation: BMC Research Notes 2008 1:17

    Content type: Short Report

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  24. Ultrastructural and biochemical abnormalities of mitochondria have been reported in skeletal muscle biopsies of CADASIL patients with mutations in the NOTCH3 nuclear gene. Additionally, it was proposed that NOTCH...

    Authors: Khaled K Abu-Amero, Ali Hellani and Saeed Bohlega

    Citation: BMC Research Notes 2008 1:16

    Content type: Short Report

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  25. Hepatitis delta virus (HDV) is a satellite virus of hepatitis B. During viral replication the 1700-nucleotide-long genomic RNA and its complement, the antigenomic RNA, undergo self-cleavage catalyzed by intern...

    Authors: Larissa Savochkina, Victoria Alekseenkova, Tatyana Belyanko, Nadezhda Dobrynina and Robert Beabealashvilli

    Citation: BMC Research Notes 2008 1:15

    Content type: Short Report

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  26. A recurrent somatic mutation, E17K, in the pleckstrin homology domain of the AKT1 gene, has been recently described in breast, colorectal, and ovarian cancers. AKT1 is a pivotal mediator of signalling pathways in...

    Authors: Hongdo Do, Benjamin Solomon, Paul L Mitchell, Stephen B Fox and Alexander Dobrovic

    Citation: BMC Research Notes 2008 1:14

    Content type: Short Report

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  27. The NORE1 protein was identified in a yeast two-hybrid screen as a Ras effector that binds Ras protein in a GTP-dependent manner. NORE1A is a growth and tumour suppressor that is inactivated in a variety of ca...

    Authors: Anna Moshnikova, Sergey Kuznetsov and Andrei V Khokhlatchev

    Citation: BMC Research Notes 2008 1:13

    Content type: Short Report

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  28. The ability of Burkholderia pseudomallei to survive in water likely contributes to its environmental persistence in endemic regions. To determine the physiological adaptations which allow B. pseudomallei to survi...

    Authors: Richard A Moore, Apichai Tuanyok and Donald E Woods

    Citation: BMC Research Notes 2008 1:11

    Content type: Short Report

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  29. Chronic diarrhoea is one of the most debilitating consequences of HIV infection in sub-Saharan Africa and it carries a high mortality rate. We report unexpectedly low concentrations of circulating aldosterone ...

    Authors: Trevor Kaile, Isaac Zulu, Ruth Lumayi, Neil Ashman and Paul Kelly

    Citation: BMC Research Notes 2008 1:10

    Content type: Short Report

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  30. Public health emergencies heighten several challenges in risk-communication: providing trustworthy sources of information, reaching marginalized populations, and minimizing fear and public confusion. In emerge...

    Authors: Elena Savoia, Michael A Stoto, Paul D Biddinger, Paul Campbell, Kasisomayajula Viswanath and Howard Koh

    Citation: BMC Research Notes 2008 1:6

    Content type: Short Report

    Published on:

  31. The comparison of DNA sequences is a traditional problem in genomics and bioinformatics. Many new opportunities emerge due to the improvement of personal computers, allowing the implementation of novel strateg...

    Authors: Vicente Arnau, Miguel Gallach and Ignacio Marín

    Citation: BMC Research Notes 2008 1:5

    Content type: Technical Note

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  32. The Alternative Splicing Mutation Database (ASMD) presents a collection of all known mutations inside human exons which affect splicing enhancers and silencers and cause changes in the alternative splicing pat...

    Authors: Jason M Bechtel, Preeti Rajesh, Irina Ilikchyan, Ying Deng, Pankaj K Mishra, Qi Wang, Xiaochun Wu, Kirill A Afonin, William E Grose, Ye Wang, Sadik Khuder and Alexei Fedorov

    Citation: BMC Research Notes 2008 1:4

    Content type: Technical Note

    Published on:

  33. In Peru, cardiovascular disease was the second most common cause of death in those aged 65 years or more in 2000. Hypertension is a major modifiable risk factor for cardiovascular disease, and if treated can s...

    Authors: Alisha R Davies, J Jaime Miranda, Robert H Gilman and Liam Smeeth

    Citation: BMC Research Notes 2008 1:2

    Content type: Short Report

    Published on:

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