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  1. Coronary artery disease (CAD) is associated with an increased risk for sudden cardiac death. Randomized controlled trials have shown that implantable cardioverter defibrillators (ICD) improve life expectancy u...

    Authors: Timo Aschenbrenner, Johannes Brockmeier, Peter Bramlage, Rolf Fimmers, Alessandro Cuneo, Stefan Hochreuther, Claudia Zemmrich and Ulrich Tebbe
    Citation: BMC Research Notes 2012 5:382
  2. The control of antibiotic production in Streptomyces coelicolor A3(2) involves complicated regulatory networks with multiple regulators controlling the expression of antibiotic biosynthetic pathways. One such reg...

    Authors: Marco Gottelt, Andrew Hesketh, Robert Bunet, Pranav Puri and Eriko Takano
    Citation: BMC Research Notes 2012 5:379
  3. To ascertain the understanding of 2009 pandemic (H1N1) influenza and relevant infection control measures in an emergency department population and to assess the effectiveness of education campaigns in informin...

    Authors: Namrata Devi Jhummon-Mahadnac, Jonathan Knott and Caroline Marshall
    Citation: BMC Research Notes 2012 5:377
  4. The St Gallen International Expert Consensus 2011 has proposed a new classification system for breast cancer. The purpose of this study was to elucidate the relationship between the breast cancer subtypes dete...

    Authors: Masumi Yanagawa, Kenzo Ikemot, Shigeto Kawauchi, Tomoko Furuya, Shigeru Yamamoto, Masaaki Oka, Atunori Oga, Yukiko Nagashima and Kohsuke Sasaki
    Citation: BMC Research Notes 2012 5:376
  5. Variations in cytokine and immune mediator expression patterns in amniotic fluid due to gestational age, maternal age and fetal gender were investigated.

    Authors: Tobias Weissenbacher, Rüdiger P Laubender, Steven S Witkin, Andrea Gingelmaier, Barbara Schiessl, Franziskus Kainer, Klaus Friese, Udo Jeschke, Darius Dian and Katrin Karl
    Citation: BMC Research Notes 2012 5:375
  6. Staphylococcus aureus is a major human pathogen causing significant morbidity and mortality. The S. aureus colonies in osteomyelitis, in patients with cystic fibrosis and patients with endoprosthesis rejection fr...

    Authors: Larisa N Churkina, Svetlana I Bidnenko, Guido Lopes dos Santos Santiago, Mario Vaneechoutte, Lilja V Avdeeva, Olga B Lutko and Nadya M Oserjanskaja
    Citation: BMC Research Notes 2012 5:374
  7. The literature on the cost-effectiveness of statin drugs in primary prevention of coronary heart disease is complex. The objective of this study is to compare the disparate results of recent cost-effectiveness...

    Authors: Aaron P Mitchell and Ross J Simpson
    Citation: BMC Research Notes 2012 5:373
  8. Acute mesenteric ischemia due to an embolism of the superior mesenteric artery is associated with a high mortality rate. Over 20 percent of acute mesenteric embolism cases consist of multiple emboli, and the l...

    Authors: Tsuyoshi Yamada, Toshitaka Yoshii, Hideya Yoshimura, Koji Suzuki and Atsushi Okawa
    Citation: BMC Research Notes 2012 5:372
  9. Prostate stem cell antigen (PSCA) has been implicated in the pathogenesis of several solid tumours, either due to changes in protein expression, or through association with the rs2294008 polymorphism in the PSCA ...

    Authors: Christopher Smith, Paul Lochhead, Umesh Basavaraju, Georgina L Hold, Nicky Fyfe, Graeme I Murray and Emad M El-Omar
    Citation: BMC Research Notes 2012 5:371
  10. General practitioners (GPs) can refer patients to an asthma/COPD service (AC-service) for diagnostic assessment of spirometry and medical history and for asthma or COPD monitoring. The AC-service reports diagn...

    Authors: Lucas EM Annelies, Derckx WCC Emmy, Meulepas A Marianne, Smeele JM Ivo, Smeenk WJM Frank and van Schayck P Onno
    Citation: BMC Research Notes 2012 5:368
  11. ACPYPE (or AnteChamber PYthon Parser interfacE) is a wrapper script around the ANTECHAMBER software that simplifies the generation of small molecule topologies and parameters for a variety of molecular dynamic...

    Authors: Alan W Sousa da Silva and Wim F Vranken
    Citation: BMC Research Notes 2012 5:367
  12. Quantitative PCR (qPCR) is a widely used technique for gene expression analysis. A common normalization method for accurate qPCR data analysis involves stable reference genes to determine relative gene express...

    Authors: Emily A Pettengill, Cécile Parmentier-Line and Gary D Coleman
    Citation: BMC Research Notes 2012 5:366
  13. Multidrug-resistant Acinetobacter baumannii, initially considered as having a poor clinical relevance, is frequently isolated from infection cases in intensive care units. We describe the epidemiology of carbapen...

    Authors: Caterina Mammina, Daniela Maria Palma, Celestino Bonura, Aurora Aleo, Teresa Fasciana, Concetta Sodano, Maria Antonietta Saporito, Maria Stella Verde, Cinzia Calà, Andrea Neville Cracchiolo and Romano Tetamo
    Citation: BMC Research Notes 2012 5:365
  14. Cytomegalovirus associated transverse myelitis among immunocompetent adults has been rarely reported. We report a patient presenting with clinical myelitis followed by previously unreported finding of cytomega...

    Authors: Suneth Karunarathne, Dumitha Govindapala, Yapa Udayakumara and Harshini Fernando
    Citation: BMC Research Notes 2012 5:364
  15. In adult population with community acquired pneumonia high levels of pro-adrenomedullin (pro-ADM) have been shown to be predictors of worse prognosis. The role of this biomarker in pediatric patients had not b...

    Authors: Marta Sardà Sánchez, Joan Calzada Hernández, Susanna Hernández-Bou, Gemma Claret Teruel, Jesús Velasco Rodríguez and Carles Luaces Cubells
    Citation: BMC Research Notes 2012 5:363
  16. There are several reports describing thousands of SSR markers in the peanut (Arachis hypogaea L.) genome. There is a need to integrate various research reports of peanut DNA polymorphism into a single platform. F...

    Authors: Yongli Zhao, Channapatna S Prakash and Guohao He
    Citation: BMC Research Notes 2012 5:362
  17. Infectious mononucleosis (IM) or Mononucleosis syndrome is caused by an acute infection of Epstein-Barr virus. In Latin American countries, there are little information pertaining to the clinical manifestation...

    Authors: Napoleón González Saldaña, Victor Antonio Monroy Colín, Georgina Piña Ruiz and Hugo Juárez Olguín
    Citation: BMC Research Notes 2012 5:361
  18. Synonymous codon usage bias has typically been correlated with, and attributed to translational efficiency. However, there are other pressures on genomic sequence composition that can affect codon usage patter...

    Authors: Mary J O'Connell, Aisling M Doyle, Thomas E Juenger, Mark TA Donoghue, Channa Keshavaiah, Reetu Tuteja and Charles Spillane
    Citation: BMC Research Notes 2012 5:359
  19. Cellular responses emerge from a complex network of dynamic biochemical reactions. In order to investigate them is necessary to develop methods that allow perturbing a high number of gene products in a flexibl...

    Authors: Sven Fengler, Philippe I H Bastiaens, Hernán E Grecco and Pedro Roda-Navarro
    Citation: BMC Research Notes 2012 5:358
  20. In Rwanda tuberculosis (TB) is one of the major health problems. To contribute to an improved performance of the Rwandan National TB Control Program, we conducted a study with the following objectives: (1) to ...

    Authors: Felix R Kayigamba, Mirjam I Bakker, Veronicah Mugisha, Michel Gasana and Maarten F Schim van der Loeff
    Citation: BMC Research Notes 2012 5:357
  21. Body temperature can be measured in seconds with tympanic thermometers as opposed to minutes with mercury ones. The aim of this study was to compare tympanic and oral mercury thermometer measurements under hig...

    Authors: Amy L Chue, Rachael L Moore, Andrew Cavey, Elizabeth A Ashley, Kasia Stepniewska, François Nosten and Rose McGready
    Citation: BMC Research Notes 2012 5:356
  22. Hip fractures are common among frail elderly persons and often have serious consequences on function, mobility and mortality. Traditional treatment of these patients is performed in orthopedic departments with...

    Authors: Ingvild Saltvedt, Anders Prestmo, Elin Einarsen, Lars Gunnar Johnsen, Jorunn L Helbostad and Olav Sletvold
    Citation: BMC Research Notes 2012 5:355
  23. Modest cognitive impairment has been reported in adults with diabetes. Therefore, we aimed to compare memory impairments among two groups of patients with diabetes with different disease durations.

    Authors: Mohamad Ali Heidari Gorji, Heshmatollah Ghahremanlu, Mohsen Haghshenas, Mohammad Reza Sadeghi and Ali Morad Heidari Gorji
    Citation: BMC Research Notes 2012 5:353
  24. There is no published information about the use of different protocols to administer a highly diluted medication.

    Authors: Denise Lessa Aleixo, Fabiana Nabarro Ferraz, Érika Cristina Ferreira, Marta de Lana, Mônica Lúcia Gomes, Benício Alves de Abreu Filho and Silvana Marques de Araújo
    Citation: BMC Research Notes 2012 5:352
  25. Understanding protein subcellular localization is a necessary component toward understanding the overall function of a protein. Numerous computational methods have been published over the past decade, with var...

    Authors: Brian R King, Suleyman Vural, Sanjit Pandey, Alex Barteau and Chittibabu Guda
    Citation: BMC Research Notes 2012 5:351
  26. PubMed is a free web literature search service that contains almost 21 millions of abstracts and publications with almost 5 million user queries daily. The purposes of the study were to compare trends in PubMe...

    Authors: Ahmed Abdelmabood Zeeneldin, Fatma Mohamed Taha and Manar Moneer
    Citation: BMC Research Notes 2012 5:349
  27. Vascular Smooth Muscle Cells (VSMCs), due to their plasticity and ability to shift from a physiological contractile-quiescent phenotype to a pathological proliferating-activated status, play a central role in ...

    Authors: Caterina Lande, Claudia Boccardi, Lorenzo Citti, Alberto Mercatanti, Milena Rizzo, Silvia Rocchiccioli, Lorena Tedeschi, Maria Giovanna Trivella and Antonella Cecchettini
    Citation: BMC Research Notes 2012 5:268
  28. Epidemiological studies revealed a strong correlation between the metabolic syndrome/diabetes mellitus type 2 (DM2) and higher incidence and faster progression of breast and colon cancer. However, the underlyi...

    Authors: Nicola M Tomas, Kai Masur, Jonas C Piecha, Bernd Niggemann and Kurt S Zänker
    Citation: BMC Research Notes 2012 5:214
  29. Aggregatibacter actinomycetemcomitans produces a leukotoxin that activates a pro-inflammatory death of human monocytes/macrophages. A specific clone of this bacterium (JP2) has a 530-base pair deletion in the leu...

    Authors: Francis Kwamin, Rolf Gref, Dorte Haubek and Anders Johansson
    Citation: BMC Research Notes 2012 5:203
  30. The increased heterogeneity in the distribution of social and biological risk factors makes the epidemiology of anaemia a real challenge. A cross-sectional study was conducted at Kassala, Eastern Sudan during ...

    Authors: Tajeldin M Abdallah, Ishag Adam, Mutaz A Abdelhadi, Mohammed F Siddig and AbdelAziem A Ali
    Citation: BMC Research Notes 2012 5:202
  31. Hospital-associated infections are an increasing cause of morbidity and mortality in veterinary patients. With the emergence of multi-drug resistant bacteria, these infections can be particularly difficult to ...

    Authors: Timothy Julian, Ameet Singh, Joyce Rousseau and J Scott Weese
    Citation: BMC Research Notes 2012 5:193
  32. Job stress is associated with adverse health effects. The present study was conducted to examine the association between sense of coherence (SOC), as advocated by Antonovsky, and psychological responses to job...

    Authors: Kayoko Urakawa, Kazuhito Yokoyama and Hiroaki Itoh
    Citation: BMC Research Notes 2012 5:247
  33. Malaria in pregnancy (MIP) is a major disease burden in Nigeria and has adverse consequences on the health of the mother, the foetus and the newborn. Information is required on how to improve its prevention an...

    Authors: Ogochukwu C Onwujekwe, Rebecca O Soremekun, Benjamin Uzochukwu, Elvis Shu and Obinna Onwujekwe
    Citation: BMC Research Notes 2012 5:211
  34. The application and better understanding of traditional and new breast tumor biomarkers and prognostic factors are increasing due to the fact that they are able to identify individuals at high risk of breast c...

    Authors: Marina P Silva, Danilo F Soave, Alfredo Ribeiro-Silva and Martin E Poletti
    Citation: BMC Research Notes 2012 5:194
  35. Epitope-mapping of infectious agents is essential for pathogenesis studies. Since polyclonal antibodies (PAbs) and monoclonal antibodies (MAbs) are always polyspecific and can react with multiple epitopes, it ...

    Authors: Andrew K I Falconar
    Citation: BMC Research Notes 2012 5:208
  36. Chronic ankle stiffness can develop for numerous reasons after traumatic injury, and may adversely affect patient gait, mobility, and function. Although standard physical therapeutic techniques typically resol...

    Authors: Christopher R Costa, Mark J McElroy, Aaron J Johnson, Bradley M Lamm and Michael A Mont
    Citation: BMC Research Notes 2012 5:348
  37. Nutrition related problems are increasing worldwide but they have scarcely been evaluated in people with neuromotor disabilities, particularly in developing countries. In this study our aim was to describe the...

    Authors: Rodrigo Vega-Sanchez, Maria de la Luz Gomez-Aguilar, Karime Haua and Guadalupe Rozada
    Citation: BMC Research Notes 2012 5:218
  38. Patients with schizophrenia frequently have disabling gait deficits. The net mechanical efficiency of walking (ϵ net ) is an accurate measure often used to evaluate walking p...

    Authors: Jørn Heggelund, Gunnar Morken, Jan Helgerud, Geir E Nilsberg and Jan Hoff
    Citation: BMC Research Notes 2012 5:344
  39. Immortalized cancer cell lines are now well-established procedures in biomedicine for a more complete understanding of cellular processes in cancer. However, they are more useful in preparation of fresh tumour...

    Authors: Luigi Minafra, Rossana Norata, Valentina Bravatà, Massimo Viola, Carmelo Lupo, Cecilia Gelfi and Cristina Messa
    Citation: BMC Research Notes 2012 5:343
  40. Angiogenesis has been reported to be one of the contributory factors to the pathogenesis of psoriasis vulgaris. This study aims to compare the expression of different angiogenesis growth factors namely (1) the...

    Authors: Siaw-Cheok Liew, Esha Das-Gupta, Srikumar Chakravarthi, Shew-Fung Wong, Nagarajah Lee, Najeeb Safdar and Adawiyah Jamil
    Citation: BMC Research Notes 2012 5:201
  41. Upper gastrointestinal (GI) bleeding is recognized as a common and potentially life-threatening abdominal emergency that needs a prompt assessment and aggressive emergency treatment. A retrospective study was ...

    Authors: Hyasinta Jaka, Mheta Koy, Anthony Liwa, Rodrick Kabangila, Mariam Mirambo, Wolfgang Scheppach, Eliasa Mkongo, Mabula D Mchembe and Phillipo L Chalya
    Citation: BMC Research Notes 2012 5:200

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