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  1. Recently, methods for measurement of dioxins in the blood have improved. Also, techniques for analyzing large quantities of data have been developed, such as data mining. Even in subjects with elusive characte...

    Authors: Shinya Matsumoto, Yoshiyuki Kanagawa, Soichi Koike, Manabu Akahane, Hiroshi Uchi, Satoko Shibata, Masutaka Furue and Tomoaki Imamura
    Citation: BMC Research Notes 2010 3:129
  2. RNA quality and quantity is sometimes unsuitable for cDNA library construction, from plant seeds rich in oil, polysaccharides and other secondary metabolites. Seeds of jatropha (Jatropha curcas L.) are rich in fa...

    Authors: Jatinder Singh Sangha, Keyu Gu, Jatinder Kaur and Zhongchao Yin
    Citation: BMC Research Notes 2010 3:126
  3. Since at least half of the genes in mammalian genomes are subjected to alternative splicing, alternative pre-mRNA splicing plays an important contribution to the complexity of the mammalian proteome. Expressed...

    Authors: Ann-Britt Nygard, Susanna Cirera, Michael J Gilchrist, Jan Gorodkin, Claus B Jørgensen and Merete Fredholm
    Citation: BMC Research Notes 2010 3:123
  4. Rapid growth in the scientific literature available on-line continues to motivate shifting data analysis from humans to computers. For example, greater knowledge of sentence characteristics indicative of inter...

    Authors: Michael A Bauer, Robert E Belford, Jing Ding and Daniel Berleant
    Citation: BMC Research Notes 2010 3:122
  5. Preterm birth remains a major public health problem and its incidence worldwide is increasing. Epidemiological risk factors have been investigated in the past, but there is a need for a better understanding of...

    Authors: Wei Yuan, Anne M Duffner, Lina Chen, Linda P Hunt, Susan M Sellers and Andrés López Bernal
    Citation: BMC Research Notes 2010 3:119
  6. Ca2+-binding proteins are important for the transduction of Ca2+ signals into physiological outcomes. As in calmodulin many of the Ca2+-binding proteins bind Ca2+ through EF-hand motifs. Amongst the large number ...

    Authors: Hannah V McCue, Lee P Haynes and Robert D Burgoyne
    Citation: BMC Research Notes 2010 3:118
  7. Epistatic interactions of multiple single nucleotide polymorphisms (SNPs) are now believed to affect individual susceptibility to common diseases. The detection of such interactions, however, is a challenging ...

    Authors: Yupeng Wang, Xinyu Liu, Kelly Robbins and Romdhane Rekaya
    Citation: BMC Research Notes 2010 3:117
  8. Prompt administration of adequate empiric antimicrobial therapy is a major determinant influencing the outcome of serious infections. The objective of this study was to describe empiric antimicrobial therapy e...

    Authors: Vikas P Chaubey, Johann DD Pitout, Bruce Dalton, Terry Ross, Deirdre L Church, Daniel B Gregson and Kevin B Laupland
    Citation: BMC Research Notes 2010 3:116
  9. In this paper a simple and cheap salting out and resin (InstaGene matrix® resin - BioRad) DNA extraction method from urine for PCR assays is introduced. The DNA of the fluke Schistosoma mansoni was chosen as the ...

    Authors: Martin J Enk, Guilherme Oliveira e Silva and Nilton B Rodrigues
    Citation: BMC Research Notes 2010 3:115
  10. There is a high prevalence of musculoskeletal disorders among healthcare professional students. Although recent studies show musculoskeletal disorders are a common problem among X-ray technologists, there are ...

    Authors: Antonio Lorusso, Luigi Vimercati and Nicola L'Abbate
    Citation: BMC Research Notes 2010 3:114
  11. Telomere length is a marker of cumulative damage to the cell, and has been associated with cardiovascular disease, hypertension, and diabetes.

    Authors: Emily W Harville, Michelle A Williams, Chun-fang Qiu, Julie Mejia and Rosa Ana Risques
    Citation: BMC Research Notes 2010 3:113
  12. We have previously reported a new nerve conduction measurement parameter which we named the Distribution of F-latency (DFL) and showed that this was an approximate mirror of the Distribution of Conduction Velo...

    Authors: Mohammad J Alam and Khondkar S Rabbani
    Citation: BMC Research Notes 2010 3:112
  13. Osteoporosis is a well-established risk factor for fall-related hip fractures. Training fall arrest strategies, such as martial arts (MA) fall techniques, might be useful to prevent hip fractures in persons wi...

    Authors: Brenda E Groen, Ellen Smulders, Jacques Duysens, Wim van Lankveld and Vivian Weerdesteyn
    Citation: BMC Research Notes 2010 3:111
  14. Methicillin-resistant Staphylococcus aureus (MRSA) is a human pathogen, representing an infection control challenge. Conventional MRSA screening takes up to three days, therefore development of rapid detection is...

    Authors: Sara Kolman, Haya Arielly and Yossi Paitan
    Citation: BMC Research Notes 2010 3:110
  15. Clinical thermometry is the objective method for temperature measurements but tactile assessment of fever at home is usually the basis for seeking medical attention especially where the cost and level of liter...

    Authors: Felix O Akinbami, Adebola E Orimadegun, Olukemi O Tongo, Olubukola O Okafor and Olusegun O Akinyinka
    Citation: BMC Research Notes 2010 3:108
  16. There has been limited research on the impact of research funding for small, institutional grants. The IWK Health Centre, a children and women's hospital in Maritime Canada, provides small amounts (up to $15,0...

    Authors: Andrew J Caddell, Jill E Hatchette and Patrick J McGrath
    Citation: BMC Research Notes 2010 3:107
  17. Although typhoid transmitted by food and water is a common problem in daily life, its characteristics and risk factors may differ in disaster-affected areas, which reinforces the need for rapid public health i...

    Authors: Agung Budi Sutiono, Andri Qiantori, Hirohiko Suwa and Toshizumi Ohta
    Citation: BMC Research Notes 2010 3:106
  18. Infections with Salmonella serotypes continue to be a significant global public health problem. In addition to contaminated foods, several other sources contribute to infections with Salmonella serotypes. We have...

    Authors: Muhammad Younus, Melinda J Wilkins, Herbert D Davies, Mohammad H Rahbar, Julie Funk, Chau Nguyen, Azfar-E A Siddiqi, Seongbeom Cho and Mahdi Saeed
    Citation: BMC Research Notes 2010 3:105
  19. Cerebral malaria is the most severe neurological complication of falciparum malaria and a leading cause of death and neuro-disability in sub-Saharan Africa. This study aimed to describe functional deficits and...

    Authors: Richard Idro, Angelina Kakooza-Mwesige, Stephen Balyejjussa, Grace Mirembe, Christine Mugasha, Joshua Tugumisirize and Justus Byarugaba
    Citation: BMC Research Notes 2010 3:104
  20. One of the main determinants of public immunization success is health professionals' support and recommendations. Little is known about the physicians' level of support and intentions regarding A(H1N1) pandemi...

    Authors: Eve Dubé, Vladimir Gilca, Chantal Sauvageau, Nicole Boulianne, François D Boucher, Julie A Bettinger, Shelly McNeil, Ian Gemmill, France Lavoie and Manale Ouakki
    Citation: BMC Research Notes 2010 3:102
  21. Due to the limited number of species specific antibodies against fish proteins, differential gene expression analyses are vital for the study of host immune responses. Quantitative real-time reverse transcript...

    Authors: Andrea A Peña, Niels C Bols and Sergio H Marshall
    Citation: BMC Research Notes 2010 3:101
  22. The ionic composition of the luminal fluid in the vestibular labyrinth is maintained within tight limits by the many types of epithelial cells bounding the lumen. Regulatory mechanisms include systemic, paracr...

    Authors: Satyanarayana R Pondugula, Nithya N Raveendran and Daniel C Marcus
    Citation: BMC Research Notes 2010 3:100
  23. The Charcot-Marie-Tooth (CMT) phenotype caused by mutation in the myelin protein zero (MPZ) gene varies considerably, from early onset and severe forms to late onset and milder forms. The mechanism is not well un...

    Authors: Geir J Braathen, Jette C Sand and Michael B Russell
    Citation: BMC Research Notes 2010 3:99
  24. Human Papillomavirus (HPV) is considered as a necessary, but not sufficient, cause of cervical cancer. In this study, we aimed to assess the prevalence of HPV in a series of pre-malignant and malignant cervica...

    Authors: José V Fernandes, Rosely V Meissner, Maria GF Carvalho, Thales AAM Fernandes, Paulo RM Azevedo, João S Sobrinho, José CM Prado and Luisa L Villa
    Citation: BMC Research Notes 2010 3:96
  25. Large phylogenies are crucial for many areas of biological research. One method of creating such large phylogenies is the supertree method, but creating supertrees containing thousands of taxa, and hence provi...

    Authors: Katie E Davis and Jon Hill
    Citation: BMC Research Notes 2010 3:95
  26. Due to its high sensitivity, the Smith-Waterman algorithm is widely used for biological database searches. Unfortunately, the quadratic time complexity of this algorithm makes it highly time-consuming. The exp...

    Authors: Yongchao Liu, Bertil Schmidt and Douglas L Maskell
    Citation: BMC Research Notes 2010 3:93
  27. Recently, the promise of a new universal long-term flu vaccine has become more tangible than ever before. Such a vaccine would protect against very many seasonal and pandemic flu strains for many years, making...

    Authors: Raffaele Vardavas, Romulus Breban and Sally Blower
    Citation: BMC Research Notes 2010 3:92
  28. Cryptosporidiosis and strongyloidiasis have been reported to be associated with HIV/AIDS. The present study was designed to determine the prevalence of Cryptosporidium and Strongyloides stercoralis infections amo...

    Authors: Amde Getaneh, Girmay Medhin and Techalew Shimelis
    Citation: BMC Research Notes 2010 3:90
  29. Microarray data interpretation can be affected by sample RNA integrity. The ScreenTape Degradation Value (SDV) is a novel RNA integrity metric specific to the ScreenTape® platform (Lab901). To characterise the pe...

    Authors: Timothy M Wilkes, Alison S Devonshire, Stephen LR Ellison and Carole A Foy
    Citation: BMC Research Notes 2010 3:89
  30. The Relative Codon Deoptimization Index (RCDI) was developed by Mueller et al. (2006) as measure of codon deoptimization by comparing how similar is the codon usage of a gene and the codon usage of a reference...

    Authors: Pere Puigbò, Lluís Aragonès and Santiago Garcia-Vallvé
    Citation: BMC Research Notes 2010 3:87
  31. The ubiquitin-based molecular switch dictating error free versus error prone repair has been conserved throughout eukaryotic evolution. A central component of this switch is the homotrimeric clamp PCNA, which ...

    Authors: Jan Brun, Roland K Chiu, Bradly G Wouters and Douglas A Gray
    Citation: BMC Research Notes 2010 3:85
  32. Typically, electrodes for Deep Brain Stimulation (DBS) are used for chronic stimulation. However, there are conditions where this therapy has to be discontinued. In such cases using the DBS electrodes as a too...

    Authors: Thomas L Hauska, Hermann Lanmüller, Wolfgang Kainz and François Alesch
    Citation: BMC Research Notes 2010 3:84
  33. Chronic diseases cause an ever-increasing percentage of morbidity and mortality, but many have modifiable risk factors. Many behaviors that predispose or protect an individual to chronic disease are interrelat...

    Authors: Federico Alonso, Carolyn O Walsh and Luis Salvador-Carulla
    Citation: BMC Research Notes 2010 3:83
  34. Many breastfeeding women seek medical care from general practitioners (GPs) for various health problems and GPs may consider prescribing medicines in these consultations. Prescribing medicines to a breastfeedi...

    Authors: Hiranya S Jayawickrama, Lisa H Amir and Marie V Pirotta
    Citation: BMC Research Notes 2010 3:82
  35. Large scale microarray experiments are becoming increasingly routine, particularly those which track a number of different cell lines through time. This time-course information provides valuable insight into t...

    Authors: Colin S Gillespie, Guiyuan Lei, Richard J Boys, Amanda Greenall and Darren J Wilkinson
    Citation: BMC Research Notes 2010 3:81
  36. microRNAs (miRNA) are short, endogenous transcripts that negatively regulate the expression of specific mRNA targets. The relative abundance of miRNAs is linked to function in vivo and miRNA expression patterns a...

    Authors: Sachin Sah, Matthew N McCall, Deepa Eveleigh, Michael Wilson and Rafael A Irizarry
    Citation: BMC Research Notes 2010 3:80
  37. Argininosuccinic aciduria (ASAuria) is an autosomal recessive disorder of the urea cycle relatively common in Saudi Arabia as a consequence of extensive consanguinity. It is the most common urea cycle disorder...

    Authors: Faiqa Imtiaz, Moeen Al-Sayed, Danyah Trabzuni, Bashair R Al-Mubarak, Osama Alsmadi, Mohamed S Rashed and Brian F Meyer
    Citation: BMC Research Notes 2010 3:79
  38. Accurate nationally representative statistics on total and cause-specific mortality in Vietnam are lacking due to incomplete capture in government reporting systems. This paper presents total and cause-specifi...

    Authors: Anh D Ngo, Chalapati Rao, Nguyen Phuong Hoa, Timothy Adair and Nguyen Thi Kim Chuc
    Citation: BMC Research Notes 2010 3:78

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