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  1. Bacteriophages infection modulates microbial consortia and transduction is one of the most important mechanism involved in the bacterial evolution. However, phage contamination brings food fermentations to a h...

    Authors: Matthias A Ehrmann, Angel Angelov, Claudia Picozzi, Roberto Foschino and Rudi F Vogel
    Citation: BMC Research Notes 2013 6:514
  2. Polymerase Chain Reaction (PCR) and Restriction Fragment Length Polymorphism of PCR products (PCR-RFLP) are extensively used molecular biology techniques. An exercise for the design and simulation of PCR and P...

    Authors: Rosario María San Millán, Ilargi Martínez-Ballesteros, Aitor Rementeria, Javier Garaizar and Joseba Bikandi
    Citation: BMC Research Notes 2013 6:513
  3. Access to Human Immunodeficiency Virus (HIV) care has been rolled out in Cameroon in the last decade through decentralised delivery of care and timely initiation of free antiretroviral drugs. We sought to desc...

    Authors: Cavin Epie Bekolo, Jayne Webster, Moses Batenganya, Gerald Etapelong Sume and Basile Kollo
    Citation: BMC Research Notes 2013 6:512
  4. The availability of genetic data has increased dramatically in recent years. The greatest value of this data is its potential for personalized medicine. Many new associations are reported every day from Genome...

    Authors: Jesus Enrique Herrera-Galeano, David L Hirschberg, Vishwesh Mokashi and Jeffrey Solka
    Citation: BMC Research Notes 2013 6:511
  5. Fiber intake may be low in individuals with chronic kidney disease (CKD) due to diet restriction and/or poor appetite associated with uremic symptoms, contributing to constipation and reduced quality of life. ...

    Authors: Younis A Salmean, Gordon A Zello and Wendy J Dahl
    Citation: BMC Research Notes 2013 6:510
  6. To define protein molecular characteristics of tumor cells prior to, and immediately following, preoperative human epidermal growth factor receptor 2 (HER2)-targeted therapy that correlate with pathologic comp...

    Authors: Frankie Ann Holmes, Virginia Espina, Lance A Liotta, Yasir M Nagarwala, Michael Danso, Kristi J McIntyre, Cynthia R C Osborne, Thomas Anderson, Lea Krekow, Joanne L Blum, John Pippen, Allison Florance, Janine Mahoney and Joyce A O’Shaughnessy
    Citation: BMC Research Notes 2013 6:507
  7. Infection with Penicillium marneffei is a common opportunistic infection in Southeast Asia where it is endemic. We report a case of Penicillium marneffei infection with fatal outcome in a Togolese woman infected ...

    Authors: Akouda Akessiwe Patassi, Bayaki Saka, Dadja Essoya Landoh, Awerou Kotosso, Koudjo Mawu, Wemboo Afiwa Halatoko, Majesté Ihou Wateba, Komi Adjoh, Osseni Tidjani, Dominique Salmon and Palokinam Pitché
    Citation: BMC Research Notes 2013 6:506
  8. In this paper, a clone based transcriptome analysis towards the identification of genes related to itaconic acid production in Aspergillus terreus was carried out as an extension of a previously published a clone...

    Authors: An Li, Martien Caspers and Peter Punt
    Citation: BMC Research Notes 2013 6:505
  9. Municipal Health Promotion Organisations (MHPOs) play an important role in promoting and disseminating prevention programmes, such as smoking prevention programmes, in schools. This study identifies factors th...

    Authors: Henricus-Paul Cremers, Anke Oenema, Liesbeth Mercken, Math Candel and Hein de Vries
    Citation: BMC Research Notes 2013 6:504
  10. High-throughput RNA sequencing studies are becoming increasingly popular and differential expression studies represent an important downstream analysis that often follow de novo transcriptome assembly. If a lo...

    Authors: Emmanuel González and Simon Joly
    Citation: BMC Research Notes 2013 6:503
  11. Vitis vinifera L. is one of society’s most important agricultural crops with a broad genetic variability. The difficulty in recognizing grapevine genotypes based on ampelographic traits and secondary metabolites ...

    Authors: Silvia Nicolè, Gianni Barcaccia, David L Erickson, John W Kress and Margherita Lucchin
    Citation: BMC Research Notes 2013 6:502
  12. Kawasaki disease is a multi-system vasculitis which usually occurs in children under 5 years of age. In infants under three months of age, it is very rare and usually associated with a high incidence of incomp...

    Authors: Salvatore Leonardi, Patrizia Barone, Giacomo Gravina, Giuseppe Fabio Parisi, Valeria Di Stefano, Pietro Sciacca and Mario La Rosa
    Citation: BMC Research Notes 2013 6:500
  13. Tacrolimus is an immunosuppressive drug used to prevent acute rejection following organ transplantation and to treat autoimmune disease. Tacrolimus is usually prescribed in such situation at a dose of 3.0 mg/d...

    Authors: Motoyasu Kato, Kazunori Tobino, Yuichi Fujimoto, Isao Kobayashi, Koji Sugano, Hitoshi Tokuda, Hiroki Ienaga and Kazuhisa Takahashi
    Citation: BMC Research Notes 2013 6:498
  14. Paragangliomas of the head and neck are rare tumors. Moreover, malignant paragangliomas of the cervical spine are extremely rare. Currently, the combination of curative surgical resection and secondary adjuvan...

    Authors: Ken Sasaki, Hiroyuki Inose, Shigenori Kawabata, Toshitaka Yoshii, Tsuyoshi Kato, Masanori Saito and Atsushi Okawa
    Citation: BMC Research Notes 2013 6:494
  15. Penetrating orbital injuries pose a serious threat to vision, ocular motility, and in some cases, life. The setting and causes of eye injury are diverse, but previous studies have demonstrated that the risk an...

    Authors: Gyanendra Malla, Rabin Bhandari, Pramendra Prasad Gupta and Rajani Giri
    Citation: BMC Research Notes 2013 6:493
  16. To evaluate the feasibility and efficacy of Stereotactic body radiation therapy (SBRT) for primary liver lesions and liver metastases treated with linear accelerators with or without rotational Intensity Modul...

    Authors: Elodie Nouhaud, Gilles Créhange, Adèle Cueff, Magali Quivrin, Magali Rouffiac-Thouant, Laurent Mineur, Robin Garcia, Jérôme Chamois and Philippe Maingon
    Citation: BMC Research Notes 2013 6:492
  17. Regardless the regulatory function of microRNAs (miRNA), their differential expression pattern has been used to define miRNA signatures and to disclose disease biomarkers. To address the question of whether pa...

    Authors: Cristhianna VA Collares, Adriane F Evangelista, Danilo J Xavier, Diane M Rassi, Thais Arns, Maria C Foss-Freitas, Milton C Foss, Denis Puthier, Elza T Sakamoto-Hojo, Geraldo A Passos and Eduardo A Donadi
    Citation: BMC Research Notes 2013 6:491
  18. Herbaceous plants containing antioxidants can protect against DNA damage. Thepurpose of this study was to evaluate the antioxidant substances,antioxidant activity, and protection of DNA from oxidative damage i...

    Authors: Kuan-Hung Lin, Yan-Yin Yang, Chi-Ming Yang, Meng-Yuan Huang, Hsiao-Feng Lo, Kuang-Chuan Liu, Hwei-Shen Lin and Pi-Yu Chao
    Citation: BMC Research Notes 2013 6:490
  19. Anaplastic lymphoma kinase-positive non-small cell lung carcinoma patients are generally highly responsive to the dual anaplastic lymphoma kinase and MET tyrosine kinase inhibitor crizotinib. However, they eventu...

    Authors: Henrik H Rossing, Morten Grauslund, Edyta M Urbanska, Linea C Melchior, Charlotte K Rask, Junia C Costa, Birgit G Skov, Jens Benn Sørensen and Eric Santoni-Rugiu
    Citation: BMC Research Notes 2013 6:489
  20. The Tei index is a Doppler-derived myocardial performance index. It is a measure of the combined systolic and diastolic myocardial performance of both the left and right ventricles. The incidence of heart fail...

    Authors: Olarinde Jeffrey Ogunmola, Anthony Olubunmi Akintomide and Adeyemi Michael Olamoyegun
    Citation: BMC Research Notes 2013 6:488
  21. Escherichia coli and Klebsiella pneumoniae are the major bacterial pathogens being isolated and reported from mid stream urine (MSU) specimens, globally. These uropathogens are mostly implicated as the major exte...

    Authors: Anil Chander and Chandrika Devi Shrestha
    Citation: BMC Research Notes 2013 6:487
  22. Acute presentation of herpes zoster (HZ) and the subsequent development of post-herpetic neuralgia (PHN) can have a significant impact on patients’ lives. To date, evidence regarding the human and economic bur...

    Authors: Stuart Carroll, Adam Gater, Linda Abetz-Webb, Fiona Smith, Dirk Demuth and Azharul Mannan
    Citation: BMC Research Notes 2013 6:486
  23. Patients with diabetes mellitus have a high risk of atherothrombotic events. Diabetes contributes for initiation and progression of microvascular and macrovascular complications. Shortened activated partial th...

    Authors: Binaya Sapkota, Saroj Kumar Shrestha and Sunil Poudel
    Citation: BMC Research Notes 2013 6:485
  24. Targeted therapy with tyrosine kinase inhibitors has been shown to reduce tumor volumes and prolong the survival of patients with metastatic renal cell carcinoma. Tyrosine kinase inhibitors, particularly sunit...

    Authors: Takuya Koie, Chikara Ohyama, Akiko Okamoto, Hayato Yamamoto, Atsushi Imai, Shingo Hatakeyama, Takahiro Yoneyama and Yasuhiro Hashimoto
    Citation: BMC Research Notes 2013 6:484
  25. As other bacteria, Mycobacterium smegmatis needs adaption mechanisms to cope with changing nitrogen sources and to survive situations of nitrogen starvation. In the study presented here, transcriptome analyses we...

    Authors: Nadja Jeßberger, Yinhua Lu, Johannes Amon, Fritz Titgemeyer, Sophia Sonnewald, Stephen Reid and Andreas Burkovski
    Citation: BMC Research Notes 2013 6:482
  26. Methanol intoxication is a dangerous situation because it often results in permanent problems such as visual deterioration, metabolic disturbances, neurological dysfunction, and even death. We present, to the ...

    Authors: Marilita M Moschos, Nikolaos S Gouliopoulos, Alexandros Rouvas and Ioannis Ladas
    Citation: BMC Research Notes 2013 6:479
  27. Dynamic left ventricular outflow tract obstruction with or without mitral regurgitation is typically observed in hypertrophic cardiomyopathy, but is also occasionally seen without left ventricular hypertrophy....

    Authors: Seonghui Kang, Sanghee An, Hyung Min Yu, Jiwan Kim, Sung Hea Kim, Hyun-Joong Kim and Sang Man Chung
    Citation: BMC Research Notes 2013 6:478
  28. Worldwide preeclampsia (PE) is the leading cause of maternal death and affects 5 to 8% of pregnant women. PE is characterized by elevated blood pressure and proteinuria. Doppler Ultrasound (US) evaluation has ...

    Authors: Maria A Lopez-Mendez, Victoria Martinez-Gaytan, Raul Cortes-Flores, Rene M Ramos-Gonzalez, Mauro A Ochoa-Torres, Idalia Garza-Veloz, Monica I Martinez-Acuña, Jose I Badillo-Almaraz and Margarita L Martinez-Fierro
    Citation: BMC Research Notes 2013 6:477
  29. Metastatic involvement of the spleen by solid tumors is a rare clinical entity; those coming from endometrial adenocarcinomas are exceptionally rare. Spleen is an uncommon site for metastatic deposits due to i...

    Authors: Adnan Arif, Zain Ul Abideen, Naeem Zia, Muhammad Atif Khan, Tariq Nawaz and Asif Zafar Malik
    Citation: BMC Research Notes 2013 6:476
  30. The objective of this study was to determine the pattern of congenital cardiac disease among children attending UNTH, Enugu, Nigeria. The nature of these abnormalities and the outcome were also considered. The...

    Authors: Josephat M Chinawa, John C Eze, Ikechukwu Obi, Ijeoma Arodiwe, Fortune Ujunwa, Adiele K Daberechi and Herbert A Obu
    Citation: BMC Research Notes 2013 6:475
  31. Skin resident microbial species are often thought of either as pathogenic or commensal. However, little is known about the role of the skin barrier in modulating their potential for causing disease. To investi...

    Authors: Patrick Duckney, Heng Kuan Wong, José Serrano, Diaraf Yaradou, Thierry Oddos and Georgios N Stamatas
    Citation: BMC Research Notes 2013 6:474
  32. Epilepsy is a common health problem which carries a huge medical social psychological and economic impact for a developing country. The aim of this hospital-based study was to get an insight into the effective...

    Authors: Mansur Habib, Sharif Uddin Khan, Md Azhahul Hoque, Md Badrul Alam Mondal, ATM Hasibul Hasan, Rajib Nayan Chowdhury, Badrul Haque, Kazi Mohibur Rahman, Ahmed Hossain Chowdhury, Swapon Kumar Ghose and Quazi Deen Mohammad
    Citation: BMC Research Notes 2013 6:473
  33. Although identification of the target mRNAs of micro RNAs (miRNAs) is essential to understanding their function, the low complementarity between miRNAs and their target mRNAs has complicated this process. In t...

    Authors: Shigeyoshi Oba, Takayuki Mizutani, Etsu Suzuki, Hiroaki Nishimatsu, Masao Takahashi, Yousuke Ogawa, Kenjiro Kimura, Yasunobu Hirata and Toshiro Fujita
    Citation: BMC Research Notes 2013 6:470
  34. Delirium is a frequently misdiagnosed and inadequately treated neuropsychiatric complication most commonly observed in terminally ill cancer patients. To our knowledge this is the first report describing delir...

    Authors: Gian Matteo Rigolin, Sara Martinelli, Luca Formigaro, Francesca Cibien, Enrico Lista, Maurizio Cavallari, Marco Ambrosio, Miriam Pizzolato, Giulia Daghia, Olga Sofritti and Antonio Cuneo
    Citation: BMC Research Notes 2013 6:469
  35. Protein–protein interactions in cells are widely explored using small–scale experiments. However, the search for protein complexes and their interactions in data from high throughput experiments such as immuno...

    Authors: Joachim Kutzera, Huub CJ Hoefsloot, Anna Malovannaya, August B Smit, Iven Van Mechelen and Age K Smilde
    Citation: BMC Research Notes 2013 6:468
  36. The appropriate positioning of nerve integrity monitoring during thyroid surgery is of relevance. In this case report we describe our experience with accurate placement of a nerve integrity monitoring endotrac...

    Authors: Savino Spadaro, Manuela D’Agata, Marco Verri, Riccardo Ragazzi and Carlo A Volta
    Citation: BMC Research Notes 2013 6:467
  37. Classical scrapie in sheep is a fatal neurodegenerative disease associated with the conversion PrPC to PrPSc. Much is known about genetic susceptibility, uptake and dissemination of PrPSc in the body, but many as...

    Authors: Siv Meling, Olav M Kvalheim, Reidar Arneberg, Kjetil BÃ¥rdsen, Anne Hjelle and Martha J Ulvund
    Citation: BMC Research Notes 2013 6:466
  38. Vermiculite is the most common soil-free growing substrate used for plants in horticultural and scientific studies due to its high water holding capacity. However, some studies are not suitable to be conducted...

    Authors: Arief Indrasumunar and Peter M Gresshoff
    Citation: BMC Research Notes 2013 6:465
  39. Food spoilage caused by molds is a severe problem. In food and feed, e.g. dairy products, sourdough bread and silage, lactic acid bacteria are used as starter cultures. Besides lactic and acetic acid, some str...

    Authors: Åsa Svanström, Silvio Boveri, Emma Boström and Petter Melin
    Citation: BMC Research Notes 2013 6:464

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