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  1. Clinical care components for people with COPD are recommended in guidelines if high-level evidence exists. However, there are gaps in their implementation, and factors which act as barriers or facilitators to ...

    Authors: Kylie Johnston, Karen Grimmer-Somers, Mary Young, Ral Antic and Peter Frith
    Citation: BMC Research Notes 2012 5:652
  2. Trochanteric fractures are common fractures in the elderly. Due to characteristic demographic changes, the incidence of these injuries is rapidly increasing. Treatment of these fractures is associated with hig...

    Authors: Benjamin Buecking, Christopher Bliemel, Johannes Struewer, Daphne Eschbach, Steffen Ruchholtz and Thorben Müller
    Citation: BMC Research Notes 2012 5:651
  3. Numerous factors like continuous habitat reduction or fragmentation for free-ranging giraffes (Giraffa camelopardalis) as well as e.g. suboptimal housing conditions for animals in captivity might lead to behaviou...

    Authors: Peter A Seeber, Isabelle Ciofolo and André Ganswindt
    Citation: BMC Research Notes 2012 5:650
  4. This study examined the effects of bovine colostrum on exercise –induced modulation of antioxidant parameters in skeletal muscle in mice. Adult male BALB/c mice were randomly divided into four groups (control,...

    Authors: Mahenderan Appukutty, Ammu Kutty Radhakrishnan, Kalavathy Ramasamy, Rajesh Ramasamy, Abu Bakar Abdul Majeed, Mohd Ismail Noor, Nik Shanita Safii, Poh Bee Koon, Karuthan Chinna and Nagaraja Haleagrahara
    Citation: BMC Research Notes 2012 5:649
  5. Double-hit lymphoma is a complex and highly aggressive sub-type of B-cell lymphoma, which has recently been classified and is an area of active research interest due to the poor prognosis for patients with thi...

    Authors: Sean D Hooper, Xiang Jiao, Elisabeth Sundström, Farah L Rehman, Christian Tellgren-Roth, Tobias Sjöblom and Lucia Cavelier
    Citation: BMC Research Notes 2012 5:648
  6. The purpose of this study was to reveal any association between cardiorespiratory fitness level and excess post-exercise oxygen consumption (EPOC) using three cycling protocols with varying degrees of exercise...

    Authors: Tomoaki Matsuo, Kazunori Ohkawara, Satoshi Seino, Nobutake Shimojo, Shin Yamada, Hiroshi Ohshima, Kiyoji Tanaka and Chiaki Mukai
    Citation: BMC Research Notes 2012 5:646
  7. The WHO guidelines were revised recently to identify patients with severe dengue (SD) early. We proceeded to determine the usefulness of the warning signs in the new WHO guidelines in predicting SD and we have...

    Authors: SD Jayaratne, Vajini Atukorale, Laksiri Gomes, Thashi Chang, Tharindu Wijesinghe, Sachie Fernando, Graham S Ogg and Gathsaurie Neelika Malavige
    Citation: BMC Research Notes 2012 5:645
  8. Replication and transcription, the two key functions of DNA, require unwinding of the DNA double helix. It has been shown that replication origins in the budding yeast, Saccharomyces cerevisiae contain an easily ...

    Authors: Mukesh P Yadav, Sreedevi Padmanabhan, Vishnu P Tripathi, Rahul K Mishra and Dharani D Dubey
    Citation: BMC Research Notes 2012 5:643
  9. Staphylococcus aureus is both human commensal and an important human pathogen, responsible for community-acquired and nosocomial infections ranging from superficial wound infections to invasive infections, such a...

    Authors: Faroq AL-Tam, Anne-Sophie Brunel, Nicolas Bouzinbi, Philippe Corne, Anne-Laure Bañuls and Hamid Reza Shahbazkia
    Citation: BMC Research Notes 2012 5:642
  10. Species of the fungal genus Trichoderma are important industrial producers of cellulases and hemicellulases, but also widely used as biocontrol agents (BCAs) in agriculture. In the latter function Trichoderma spe...

    Authors: Sabine Gruber, Markus Omann, Carolina Escobar Rodrìguez, Theresa Radebner and Susanne Zeilinger
    Citation: BMC Research Notes 2012 5:641
  11. Serum total cholesterol (TC) and LDL cholesterol (LDL-C) have been used as major laboratory measures in clinical practice to assess cardiovascular risk in the general population and disease management as well ...

    Authors: Manoj Sigdel, Binod Kumar Yadav, Prajwal Gyawali, Prashant Regmi, Sushil Baral, Shyam Raj Regmi and Bharat Jha
    Citation: BMC Research Notes 2012 5:640
  12. Lymphangitic carcinomatosis as a manifestation of gastric carcinoma is rare. The presenting symptoms are misleading and nonspecific, often resulting in delayed diagnosis.

    Authors: Kim Moubax, Wim Wuyts, Vincent Vandecaveye and Hans Prenen
    Citation: BMC Research Notes 2012 5:638
  13. Bacterial vaginosis (BV) is a common pathology of women in reproductive age that can lead to serious health complications, and is associated with shifts in the normal microflora from predominance of Lactobacillus

    Authors: Ana Henriques, Tatiana Cereija, António Machado and Nuno Cerca
    Citation: BMC Research Notes 2012 5:637
  14. Transforming growth factor-β (TGF-β) is a multi-factorial peptide growth factor that has a vital role in the regulation of cell growth, differentiation, inflammation, and tissue repair. Quantification of biolo...

    Authors: Shaukat A Khan, Jennifer Joyce and Takeshi Tsuda
    Citation: BMC Research Notes 2012 5:636
  15. Japanese nurses are increasingly required to read published international research in clinical, educational, and research settings. Language barriers are a significant obstacle, and online machine translation ...

    Authors: Ryoko Anazawa, Hirono Ishikawa, MJ Park and Takahiro Kiuchi
    Citation: BMC Research Notes 2012 5:635
  16. The genus Eucalyptus consists of approximately 600 species and subspecies and has a physiological plasticity that allows some species to propagate in different regions of the world. Eucalyptus is a major source o...

    Authors: Jullyana Cristina Magalhães Silva Moura, Pedro Araújo, Michael dos Santos Brito, Uiara Romero Souza, Julianade Oliveira Fernandes Viana and Paulo Mazzafera
    Citation: BMC Research Notes 2012 5:634
  17. Nucleic acid aptamers have long demonstrated the capacity to bind viral envelope proteins and to inhibit the progression of pathogenic virus infections. Here we report on initial efforts to develop and screen ...

    Authors: John G Bruno, Maria P Carrillo, Alicia M Richarte, Taylor Phillips, Carrie Andrews and John S Lee
    Citation: BMC Research Notes 2012 5:633
  18. We have recently described a method for the construction of an informative gene expression correlation landscape for a single tissue, longissimus muscle (LM) of cattle, using a small number (less than a hundre...

    Authors: Wei Sun, Nicholas J Hudson, Antonio Reverter, Ashley J Waardenberg, Ross L Tellam, Tony Vuocolo, Keren Byrne and Brian P Dalrymple
    Citation: BMC Research Notes 2012 5:632
  19. BMC Research Notes recently published a research article regarding the use of ligated DNA extracted from formalin-fixed paraffin embedded (FFPE) tissue on the Illumina Infinium methylation platform - “Interpre...

    Authors: Christina Thirlwell, Andrew Feber, Matthias Lechner, Andrew E Teschendorff and Stephan Beck
    Citation: BMC Research Notes 2012 5:631
  20. Asthma is a complex disease characterized by hyperresponsiveness, obstruction and inflammation of the airways. To date, several studies using different approaches as candidate genes approach, genome wide assoc...

    Authors: Vanessa T Vaillancourt, Martine Bordeleau, Michel Laviolette and Catherine Laprise
    Citation: BMC Research Notes 2012 5:630
  21. Human ß-defensins are a family of antimicrobial peptides located at the mucosal surface. Both sequence multi-site variations (MSV) and copy-number variants (CNV) of the defensin-encoding genes are associated w...

    Authors: Stefan Taudien, Gabor Gäbel, Oliver Kuss, Marco Groth, Robert Grützmann, Klaus Huse, Alexander Kluttig, Andreas Wolf, Michael Nothnagel, Philip Rosenstiel, Karin Halina Greiser, Karl Werdan, Michael Krawczak, Christian Pilarsky and Matthias Platzer
    Citation: BMC Research Notes 2012 5:629
  22. To study and update the provincial incidence of type 1 diabetes mellitus (T1DM) in Newfoundland and Labrador (NL), a province of Canada with a very high incidence previously reported in 2006, and one of the hi...

    Authors: Leigh A Newhook, Sharon Penney, Jackie Fiander and Jeff Dowden
    Citation: BMC Research Notes 2012 5:628
  23. Breast cancer is one of the leading causes of cancer morbidity and mortality worldwide. In Cameroon, breast cancer causes as many as 10.7 deaths per 100,000 women making it the second cause of cancer mortality...

    Authors: Mary Atanga Bi Suh, Julius Atashili, Eunice Asoh Fuh and Vivian Ayamba Eta
    Citation: BMC Research Notes 2012 5:627
  24. Hyperelastosis cutis is an inherited autosomal recessive connective tissue disorder. Affected horses are characterized by hyperextensible skin, scarring, and severe lesions along the back. The disorder is caus...

    Authors: Sergei P Boudko, Yoshihiro Ishikawa, Thomas F Lerch, Jay Nix, Michael S Chapman and Hans Peter Bächinger
    Citation: BMC Research Notes 2012 5:626
  25. In plants, a large family of calmodulin (CaM) and CaM-like (CML) proteins transduce the increase in cytosolic Ca2+ concentrations by binding to and altering the activities of target proteins, and thereby affectin...

    Authors: Aumnart Chinpongpanich, Kampon Limruengroj, Srivilai Phean-o-pas, Tipaporn Limpaseni and Teerapong Buaboocha
    Citation: BMC Research Notes 2012 5:625
  26. To improve equity in access to medical research, successful strategies are needed to recruit diverse populations. Here, we examine experiences of community health center (CHC) staff who guided an informed cons...

    Authors: Heather E Riden, Kya N Grooms, Cheryl R Clark, Laura R Cohen, Josh Gagne, Dora A Tovar, Mark J Ommerborn, Piper S Orton and Paula A Johnson
    Citation: BMC Research Notes 2012 5:624
  27. Determining the genes responsible for certain human traits can be challenging when the underlying genetic model takes a complicated form such as heterogeneity (in which different genetic models can result in t...

    Authors: Jeffrey J Gory, Holly C Sweeney, David M Reif and Alison A Motsinger-Reif
    Citation: BMC Research Notes 2012 5:623
  28. Complete hydatiform mole and coexistent viable fetus is very rare. The use of a cervical cerclage for cervical indications in the presence of this condition has never been reported. Although the diagnosis was ...

    Authors: Eduardo Aguin, Victor Aguin, Ligia Cisneros, Tina Aguin, Cosmas Van de ven and Ray Bahado-Singh
    Citation: BMC Research Notes 2012 5:621
  29. Increased interest in health care cost containment is focusing attention on reduction of hospital readmissions. Major payors have already developed financial penalties for providers that generate excess readmi...

    Authors: Ronald J Lagoe, Diane S Nanno and Mary E Luziani
    Citation: BMC Research Notes 2012 5:620
  30. Our previous study on ripe apples from a progeny of a cross between the apple cultivars ‘Prima’ and ‘Fiesta’ showed a hotspot of mQTLs for phenolic compounds at the top of LG16, both in peel and in flesh tissu...

    Authors: Sabaz Ali Khan, Jan G Schaart, Jules Beekwilder, Andrew C Allan, Yury M Tikunov, Evert Jacobsen and Henk J Schouten
    Citation: BMC Research Notes 2012 5:618
  31. The tissue-specific Unigene Sets derived from more than one million expressed sequence tags (ESTs) in the NCBI, GenBank database offers a platform for identifying significantly and differentially expressed tis...

    Authors: Mousami Srivastava, Pankaj Khurana and Ragumani Sugadev
    Citation: BMC Research Notes 2012 5:617
  32. Toll-like receptors (TLRs) are evolutionarily conserved pattern recognition receptors that mediate host responses to pathogens. To date, at least 10 different TLRs have been identified in chickens including TL...

    Authors: Michael St Paul, Neda Barjesteh, Sarah Paolucci, Yanlong Pei and Shayan Sharif
    Citation: BMC Research Notes 2012 5:616
  33. Evaluating the impact of genomic variations (GV) on protein-coding transcripts is an important step in identifying variants of functional significance. Currently available programs for variant annotation depen...

    Authors: Ismael A Vergara, Christian Frech and Nansheng Chen
    Citation: BMC Research Notes 2012 5:615
  34. Body-focused repetitive behaviors (BFRBs) that include skin picking (dermatillomania), hair pulling (trichotillomania) and nail biting (onychophagia), lead to harmful physical and psychological sequelae.

    Authors: Efaza Umar Siddiqui, Syed Saad Naeem, Haider Naqvi and Bilal Ahmed
    Citation: BMC Research Notes 2012 5:614
  35. The acceptability of female-controlled biomedical prevention technologies has not been established in Papua New Guinea, the only country in the Pacific region experiencing a generalised, moderate-prevalence HI...

    Authors: Andrew Vallely, Lisa Fitzgerald, Voletta Fiya, Herick Aeno, Angela Kelly, Joyce Sauk, Martha Kupul, James Neo, John Millan, Peter Siba and John M Kaldor
    Citation: BMC Research Notes 2012 5:613
  36. Human plasma, representing the most complete record of the individual phenotype, is an appealing sample for proteomics analysis in clinical applications. Up to today, the major obstacle in a proteomics study o...

    Authors: Claudia Boccardi, Silvia Rocchiccioli, Antonella Cecchettini, Alberto Mercatanti and Lorenzo Citti
    Citation: BMC Research Notes 2012 5:612
  37. In Germany, case management in a palliative care unit was first implemented in 2005 at the Department of Palliative Medicine at the University Hospital Cologne. One of the purposes of this case management is t...

    Authors: Ulrike Kuhn, Anne Düsterdiek, Maren Galushko, Christina Dose, Thomas Montag, Christoph Ostgathe and Raymond Voltz
    Citation: BMC Research Notes 2012 5:611
  38. Image registration is one of the most important and universally useful computational tasks in biomedical image analysis. A recent article by Xing & Qiu (IEEE Transactions on Pattern Analysis and Machine Intell...

    Authors: Torsten Rohlfing and Brian Avants
    Citation: BMC Research Notes 2012 5:610
  39. Clostridium difficile ribotype 027 has become increasingly prevalent in European countries. The clinical picture varies from self-limiting diarrhea to pseudomembranous colitis with toxic megacolon and ultimately ...

    Authors: Kirstine Kobberøe Søgaard, Tove Ejlertsen and Henrik Carl Schønheyder
    Citation: BMC Research Notes 2012 5:609
  40. Heterotrimeric G-proteins, consisting of three subunits Gα, Gβ and Gγ are present in most eukaryotes and mediate signaling in numerous biological processes. In plants, Gγ subunits were shown to provide functio...

    Authors: Yuri Trusov, David Chakravorty and José Ramón Botella
    Citation: BMC Research Notes 2012 5:608
  41. Bladder cancer is the seventh most common cancer worldwide and over 90% are transitional cell carcinoma (TCC). At the first time of diagnosis at least 70% of TCC present as superficial bladder cancer. Because ...

    Authors: Donatella Conconi, Elena Panzeri, Serena Redaelli, Giorgio Bovo, Marco Volante, Paolo Viganò, Guido Strada, Leda Dalprà and Angela Bentivegna
    Citation: BMC Research Notes 2012 5:607
  42. Investigators conduct survey studies for a variety of reasons. Poor participant response rates are common, however, and may limit the generalizability and utility of results. The objective of this study was to...

    Authors: Melissa J Parker, Asmaa Manan and Sara Urbanski
    Citation: BMC Research Notes 2012 5:605
  43. In the big data era, biomedical research continues to generate a large amount of data, and the generated information is often stored in a database and made publicly available. Although combining data from mult...

    Authors: Mizuki Morita, Yoshinobu Igarashi, Maori Ito, Yi-An Chen, Chioko Nagao, Yuki Sakaguchi, Ryuichi Sakate, Tohru Masui and Kenji Mizuguchi
    Citation: BMC Research Notes 2012 5:604

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