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  1. Coiled-coils are found in different proteins like transcription factors, myosin tail domain, tropomyosin, leucine zippers and kinesins. Analysis of various structures containing coiled-coils has revealed the i...

    Authors: Margaret S Sunitha, Anu G Nair, Amol Charya, Kamalakar Jadhav, Sami Mukhopadhyay and Ramanathan Sowdhamini
    Citation: BMC Research Notes 2012 5:530
  2. Highly infectious diseases (HIDs) are defined as being transmissible from person to person, causing life-threatening illnesses and presenting a serious public health hazard. The sampling, handling and transpor...

    Authors: Simon-Djamel Thiberville, Stefan Schilling, Giuseppina De Iaco, Francesco Maria Fusco, Gail Thomson, Helen C Maltezou, Rene Gottschalk, Reinhard H Brodt, Barbara Bannister, Vincenzo Puro, Giuseppe Ippolito and Philippe Brouqui
    Citation: BMC Research Notes 2012 5:527
  3. For several decades, overcrowding in emergency departments (EDs) has been intensifying due to the increased number of patients seeking care in EDs. Demand growth is partly due to misuse of EDs by patients who ...

    Authors: Anne-Claire Durand, Sylvie Palazzolo, Nicolas Tanti-Hardouin, Patrick Gerbeaux, Roland Sambuc and Stéphanie Gentile
    Citation: BMC Research Notes 2012 5:525
  4. Despite evidence suggesting that the Liverpool Care Pathway for the Dying Patient is a structured and proficient means of supporting care delivery in the last hours or days of life, discrepancies in uptake are...

    Authors: Alison Freemantle and Jane Seymour
    Citation: BMC Research Notes 2012 5:524
  5. Few studies have investigated sexual dysfunction in immigrant patients with type 2 diabetes in Sweden. The aim of this study was to examine the association between ethnicity and sexual dysfunction and to analy...

    Authors: Marina Taloyan, Alexandre Wajngot, Sven-Erik Johansson, Jonas Tovi and Kristina Sundquist
    Citation: BMC Research Notes 2012 5:522
  6. The Kinetic Simulation Algorithm Ontology (KiSAO) supplies information about existing algorithms available for the simulation of Systems Biology models, their characteristics, parameters and inter-relationship...

    Authors: Anna Zhukova, Richard Adams, Camille Laibe and Nicolas Le Novère
    Citation: BMC Research Notes 2012 5:520
  7. Mode of delivery has been reported to affect the cord blood glucose level of newborns. Vaginally delivered (VD) newborns were found to have relatively increased concentration of cord blood glucose than those d...

    Authors: Mulugeta Melkie, Mahilet Yigeremu, Paulos Nigussie, Tilahun Teka and Samuel Kinde
    Citation: BMC Research Notes 2012 5:519
  8. Current research in network reverse engineering for genetic or metabolic networks very often does not include a proper experimental and/or input design. In this paper we address this issue in more detail and s...

    Authors: Johannes D Stigter and Jaap Molenaar
    Citation: BMC Research Notes 2012 5:518
  9. Hepatocyte Growth Factor (HGF) enhances cytotoxicity of paclitaxel (PTX) and cisplatin (CDDP) in human ovarian cancer cells. Because of potential pitfalls of HGF exogenous administration, we investigated wheth...

    Authors: Anna Surbone, Luca Fuso, Roberto Passera, Annamaria Ferrero, Cristiana Marchese, Cosimo Martino, Annalisa Luchin, Maria Flavia Di Renzo and Paolo Zola
    Citation: BMC Research Notes 2012 5:517
  10. Double chambered right ventricle (DCRV) is a relatively rare congenital heart disease, characterized by the abnormal division of the right ventricle into a high-pressure inlet and low-pressure outlet by anomal...

    Authors: Lan-Chau Kha, Alessandra Cassano-Bailey, Kelby Cleverley, Maneesh Sud, Jacek Strzelczyk and Davinder S Jassal
    Citation: BMC Research Notes 2012 5:516
  11. In 2006, the Dutch government initiated Hello World, an email-based program promoting healthy lifestyles among pregnant women through quizzes with pregnancy-related questions. In 2008, an updated version was r...

    Authors: Johanna M van Dongen, Mireille NM van Poppel, Ivon EJ Milder, Hans AM van Oers and Johannes Brug
    Citation: BMC Research Notes 2012 5:514
  12. We describe a method for subcellular fractionation of mouse skeletal muscle, myoblast and myotubes to obtain relatively pure fractions of nuclear, cytosolic and mitochondrial compartments. Fractionation allows...

    Authors: Ivan Dimauro, Timothy Pearson, Daniela Caporossi and Malcolm J Jackson
    Citation: BMC Research Notes 2012 5:513
  13. General practitioners (GPs) play a central role in disseminating information and most health policies are tending to develop this pivotal role of GPs in dissemination of health-related information to the publi...

    Authors: Maxine Gignon, Hadjila Idris, Cecile Manaouil and Oliver Ganry
    Citation: BMC Research Notes 2012 5:511
  14. The Norwegian Mother and Child Cohort Study (MoBa) is a nation-wide population-based pregnancy cohort initiated in 1999, comprising more than 108.000 pregnancies recruited between 1999 and 2008. In this study ...

    Authors: Nur Duale, Gunnar Brunborg, Kjersti S Rønningen, Thomas Briese, Jeanette Aarem, Kaja K Aas, Per Magnus, Camilla Stoltenberg, Ezra Susser and W Ian Lipkin
    Citation: BMC Research Notes 2012 5:510
  15. The cirrhosis complications hepatic encephalopathy, ascites, and variceal bleeding increase mortality but develop in random sequence. Therefore prognoses based on the presence or absence of these clinical comp...

    Authors: Peter Jepsen, Peter Ott, Per Kragh Andersen and Hendrik Vilstrup
    Citation: BMC Research Notes 2012 5:509
  16. Cytokines play an important role in the regulation of the immune response. In hepatitis C virus (HCV) infection, cytokine levels may influence the outcome of acute HCV infection. Polymorphisms in cytokine gene...

    Authors: Juliene Antonio Ramos, Rosane Silva, Luísa Hoffmann, Ana Lucia Araújo Ramos, Pedro Hernan Cabello, Turán Péter Ürményi, Cristiane Alves Villella-Nogueira, Lia Lewis-Ximenez and Edson Rondinelli
    Citation: BMC Research Notes 2012 5:508
  17. Medulloblastoma (MB) is the most common type of malignant childhood brain tumour. Although deregulated microRNA (miRNA) expression has been linked to MB pathogenesis, the selection of appropriate candidate end...

    Authors: Laura A Genovesi, Denise Anderson, Kim W Carter, Keith M Giles and Peter B Dallas
    Citation: BMC Research Notes 2012 5:507
  18. RNA sequencing (RNA-Seq) is emerging as a highly accurate method to quantify transcript abundance. However, analyses of the large data sets obtained by sequencing the entire transcriptome of organisms have gen...

    Authors: Craig R Yendrek, Elizabeth A Ainsworth and Jyothi Thimmapuram
    Citation: BMC Research Notes 2012 5:506
  19. Mitochondrial morphology is maintained by two distinct membrane events -fission and fusion. Altering these conserved processes can disrupt mitochondrial morphology and distribution, thereby disrupting the orga...

    Authors: Brixey G Schimmel, Gregory W Berbusse and Kari Naylor
    Citation: BMC Research Notes 2012 5:505
  20. The use of computer assisted learning (CAL) has enhanced undergraduate medical education. CAL improves performance at examinations, develops problem solving skills and increases student satisfaction. The study...

    Authors: Priyanga Ranasinghe, Sashimali A Wickramasinghe, WA Rasanga Pieris, Indika Karunathilake and Godwin R Constantine
    Citation: BMC Research Notes 2012 5:504
  21. The ability to transport and store DNA at room temperature in low volumes has the advantage of optimising cost, time and storage space. Blood spots on adapted filter papers are popular for this, with FTA (Flin...

    Authors: Katie E Fowler, Chris P Reitter, Grant A Walling and Darren K Griffin
    Citation: BMC Research Notes 2012 5:503
  22. Young people between the ages of 15 and 24 years are both the most at risk of HIV and the greatest hope for turning the tide against HIV/AIDS. Although various surveys have been done on sexual behaviour of you...

    Authors: Belaynew Wasie, Yeshambel Belyhun, Beyene Moges and Bemnet Amare
    Citation: BMC Research Notes 2012 5:501
  23. Russell’s viper (Daboia russelli) bites lead to high morbidity and mortality in South Asia. Although variety of clinical manifestations is reported in viper bite victims, myocardial ischemic events are rare.

    Authors: Anjana Silva, Senaka Pilapitiya and Sisira Siribaddana
    Citation: BMC Research Notes 2012 5:500
  24. The biggest barrier to treatment of common mental disorders in primary care settings is low recognition among health care providers. This study attempts to explore the explanatory models of common mental disor...

    Authors: Gracy Andrew, Alex Cohen, Shruti Salgaonkar and Vikram Patel
    Citation: BMC Research Notes 2012 5:499
  25. In 2007, the patient’s right to specialised palliative home care became law in Germany. However, childhood palliative care in territorial states with low patient numbers and long distances requires adapted mod...

    Authors: Kerstin Kremeike, Nina Eulitz, Saskia Jünger, Annette Sander, Max Geraedts and Dirk Reinhardt
    Citation: BMC Research Notes 2012 5:498
  26. Both environmental and genetic factors contribute to individual susceptibility to initiation of substance use and vulnerability to addiction. Determining genetic risk factors can make an important contribution...

    Authors: Laith N AL-Eitan, Saied A Jaradat, Gary K Hulse and Guan K Tay
    Citation: BMC Research Notes 2012 5:497
  27. Pregnancies complicated by pre-existing diabetes mellitus (PDM) are associated with a high rate of adverse outcomes, including an increased miscarriage rate, preterm delivery, preeclampsia, perinatal mortality...

    Authors: Hayfaa A Wahabi, Samia A Esmaeil, Amel Fayed, Ghadeer Al-Shaikh and Rasmieh A Alzeidan
    Citation: BMC Research Notes 2012 5:496
  28. Protein-protein interactions form the core of several biological processes. With protein-protein interfaces being considered as drug targets, studies on their interactions and molecular mechanisms are gaining ...

    Authors: Seema Mishra
    Citation: BMC Research Notes 2012 5:495
  29. Copyright and licensing of scientific data, internationally, are complex and present legal barriers to data sharing, integration and reuse, and therefore restrict the most efficient transfer and discovery of s...

    Authors: Iain Hrynaszkiewicz and Matthew J Cockerill
    Citation: BMC Research Notes 2012 5:494
  30. Reference intervals (RIs) are ranges of upper and lower limits of a given analyte which are used for a laboratory test to determine whether a disease is present or absent or to know if the patient is at risk f...

    Authors: Mulugeta Melkie, Mahilet Yigeremu, Paulos Nigussie, Shawel Asrat, Tatek Gebreegziabher, Tilahun Teka and Samuel Kinde
    Citation: BMC Research Notes 2012 5:493
  31. Overweight and obesity is a growing problem in Ireland. Many parents are unaware when their child is overweight or obese. Our objectives were to examine parents’ perceptions of a healthy diet and their childre...

    Authors: Aisling Flinn, Alan P Macken, Walter Cullen, Des Leddin, Colum Dunne and Clodagh S O’Gorman
    Citation: BMC Research Notes 2012 5:491
  32. There is much concern regarding undisclosed corporate authorship (“ghostwriting”) in the peer-reviewed medical literature. However, there are no studies of how disclosure of ghostwriting alone impacts the perc...

    Authors: Jeffrey R Lacasse, Jonathan Leo, Andrea N Cimino, Kristen F Bean and Melissa Del-Colle
    Citation: BMC Research Notes 2012 5:490
  33. A health demographic surveillance system (HDSS) provides longitudinal data regarding health and demography in countries with coverage error and poor quality data on vital registration systems due to lack of pu...

    Authors: Umesh Raj Aryal, Abhinav Vaidya, Suraj Shakya-Vaidya, Max Petzold and Alexandra Krettek
    Citation: BMC Research Notes 2012 5:489
  34. Varicose veins are a common entity presenting a worldwide distribution. Although they are usually benign, sometimes are proved to be a threatening condition. Massive hemorrhage is an unusual complication of th...

    Authors: Kleio Fragkouli, Antigoni Mitselou, Vassiliki A Boumba, George Siozios, George T Vougiouklakis and Theodore Vougiouklakis
    Citation: BMC Research Notes 2012 5:488
  35. Nucleic acid amplification tests (NAATs) have offered hope for rapid diagnosis of tuberculosis (TB). However, their efficiency with smear-negative samples has not been widely studied in low income settings. He...

    Authors: Lydia Nakiyingi, David P Kateete, Ponsiano Ocama, William Worodria, Joseph B Sempa, Benon B Asiimwe, Fred A Katabazi, Achilles Katamba, Laurence Huang, Moses L Joloba and Harriet Mayanja-Kizza
    Citation: BMC Research Notes 2012 5:487
  36. Although it is taken for granted that history-taking and communication skills are learnable, this learning process should be confirmed by rigorous studies, such as randomized pre- and post-comparisons. The pur...

    Authors: Anne Simmenroth-Nayda, Cora Weiss, Thomas Fischer and Wolfgang Himmel
    Citation: BMC Research Notes 2012 5:486
  37. The flavonoid pathway is a long-standing and important tool for plant genetics, biochemistry, and molecular biology. Numerous flavonoid mutants have been identified in Arabidopsis over the past several decades in...

    Authors: Peter A Bowerman, Melissa V Ramirez, Michelle B Price, Richard F Helm and Brenda SJ Winkel
    Citation: BMC Research Notes 2012 5:485
  38. Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections (LRTIs) in children globally. Predisposing conditions for the development of serious RSV disease include preterm infan...

    Authors: Tatyana V Turti, Elena N Baibarina, Elena A Degtiareva, Elena S Keshishyan, Yurii V Lobzin, Leyla S Namazova-Вaranova, Andrey P Prodeus, Konstantin M Gudkov, Anna I Kruglova, Gregory A Schulz and Gerard F Notario
    Citation: BMC Research Notes 2012 5:484
  39. In 2009, a novel influenza A/H1N1 virus (H1N1pdm) quickly spread worldwide and co-circulated with then-existing seasonal H1N1 virus (sH1N1). Distinguishing between these 2 viruses was necessary to better chara...

    Authors: Yoshihiro Kaku, Akira Noguchi, Akiko Okutani, Satoshi Inoue, Kiyoshi Tanabayashi, Yoshie Yamamoto, Akitoyo Hotta, Michio Suzuki, Naoko Sugiura and Akio Yamada
    Citation: BMC Research Notes 2012 5:483
  40. Although first-line therapy for patients affected by advanced mesothelioma is well established, there is a lack of data regarding the impact of second-line treatment.

    Authors: Alessandra Bearz, Renato Talamini, Gilda Rossoni, Antonio Santo, Vincenzo de Pangher, Gianpiero Fasola, Francesco Rosetti, Adolfo Favaretto, Vanesa Gregorc, Massimiliano Berretta, Sandra Santarossa, Eleonora Berto and Umberto Tirelli
    Citation: BMC Research Notes 2012 5:482
  41. Intestinal malrotation is an incomplete rotation of the intestine. Failure to rotate leads to abnormalities in intestinal positioning and attachment that leave obstructing bands across the duodenum and a narro...

    Authors: Takuma Matsuki, Akimune Kaga, Susumu Kanda, Yutaka Suzuki, Muneyuki Tanabu and Naoya Sawa
    Citation: BMC Research Notes 2012 5:481
  42. The present study sought to determine if subjects who had consumed coffee before performing a simulated computer office-work task found to provoke pain in the neck and shoulders and forearms and wrists exhibit...

    Authors: Vegard Strøm, Cecilie Røe and Stein Knardahl
    Citation: BMC Research Notes 2012 5:480
  43. Viral infections during pregnancy can pose serious threats to mother and fetus from the time of conception to the time of delivery. These lead to congenital defects, spontaneous abortion and even death. The de...

    Authors: Joseph Humphrey Kofi Bonney, Robert A Kwame-Aryee, Samuel Obed, Ama Asantewa Tamatey, Jacob Samson Barnor, Naa Baake Armah, Samuel Antwi Oppong and Mubarak Osei-Kwesi
    Citation: BMC Research Notes 2012 5:478

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