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  1. The Grin1 (glutamate receptor, ionotropic, NMDA1) gene expresses a subunit of N-methyl-D-aspartate (NMDA) receptors that is considered to play an important role in excitatory neurotransmission, synaptic plasticit...

    Authors: Juzoh Umemori, Keizo Takao, Hisatsugu Koshimizu, Satoko Hattori, Tamio Furuse, Shigeharu Wakana and Tsuyoshi Miyakawa
    Citation: BMC Research Notes 2013 6:203
  2. Despite major public health initiatives and the existence of efficacious treatment regimes, tuberculosis (TB) remains a threat, particularly in resource-limited settings. A significant part of the problem is t...

    Authors: Liya Wassie, Markos Abebe, Abraham Aseffa, Kidist Bobosha, Martha Zewdie, Menberwork Chanyalew, Lawrence K Yamuah, Arantxa Cortés, Jose R González, Jose M Delgado, Ismail Ceyhan, Ida Rosenkrands, Karin Weldingh, Peter Andersen and Timothy Mark Doherty
    Citation: BMC Research Notes 2013 6:202
  3. Saccharomyces cerevisiae is extensively used in bio-industries. However, its genetic engineering to introduce new metabolism pathways can cause unexpected phenotypic alterations. For example, humanisation of the ...

    Authors: Christine Bonnet, Céline Rigaud, Emilie Chanteclaire, Claire Blandais, Emilie Tassy-Freches, Christelle Arico and Christophe Javaud
    Citation: BMC Research Notes 2013 6:201
  4. We document clinical manifestations of 21 patients heavily infected with S. stercoralis (more than 250 larvae in a single Baermann test) from a community in rural Cambodia, both before and three weeks after iverm...

    Authors: Virak Khieu, Sophanaroth Srey, Fabian Schär, Sinuon Muth, Hanspeter Marti and Peter Odermatt
    Citation: BMC Research Notes 2013 6:200
  5. To generate clinically applicable reference intervals (RIs) for commonly requested electrolytes in Ethiopian newborns and infants that can help in early detection, close monitoring and correction of electrolyt...

    Authors: Mulugeta Melkie, Mahilet Yigeremu, Paulos Nigussie, Tilahun Teka and Samuel Kinde
    Citation: BMC Research Notes 2013 6:199
  6. Thyroid storm is a serious condition of thyrotoxicosis. Hyperthyroidism often presents with thrombotic events, especially at cerebral sites; however, the possible association between a lower extremity deep vei...

    Authors: Taro Umezu, Keigo Ashitani, Takahiro Toda and Tatsuo Yanagawa
    Citation: BMC Research Notes 2013 6:198
  7. Antioxidant, one of the most important food additives, is widely used in food industry. At present, antioxidant is mostly produced by chemical synthesis, which would accumulate to be pathogenic. Therefore, a g...

    Authors: Juan Wang, Yansheng Wang, Xiangli Dang, Xiaoxia Zheng and Wenqing Zhang
    Citation: BMC Research Notes 2013 6:197
  8. Soybean pathogens and pests reduce grain production worldwide. Biotic interaction cause extensive changes in plant gene expression profile and the data produced by functional genomics studies need validation, ...

    Authors: Vívian de Jesus Miranda, Roberta Ramos Coelho, Antônio Américo Barbosa Viana, Osmundo Brilhante de Oliveira Neto, Regina Maria Dechechi Gomes Carneiro, Thales Lima Rocha, Maria Fatima Grossi de Sa and Rodrigo Rocha Fragoso
    Citation: BMC Research Notes 2013 6:196
  9. Gallstone ileus accounts for 1% to 4% of cases of mechanical bowel obstruction, but may be responsible for up to 25% of cases in older age groups. In non-iatrogenic cases, gallstone migration occurs after form...

    Authors: Celso Nabais, Raquel Salústio, Inês Morujão, Francisco V Sousa, Eusébio Porto, Carlos Cardoso and Caldeira Fradique
    Citation: BMC Research Notes 2013 6:195
  10. Toxoplasmosis is a worldwide infection caused by the protozoan parasite Toxoplasma gondii, which causes chorioretinitis and neurological defects in congenitally infected newborns or immunodeficient patients. The ...

    Authors: Maria L Alomar, Federico AO Rasse-Suriani, Agustina Ganuza, Verónica M Cóceres, Franco M Cabrerizo and Sergio O Angel
    Citation: BMC Research Notes 2013 6:193
  11. Mice homozygous for the spontaneous wooly mutation (abbreviated wly) are recognized as early as 3–4 weeks of age by the rough or matted appearance of their coats. Previous genetic analysis has placed wly in a 5.9...

    Authors: Legairre A Radden, Kevin M Child, Elisabeth B Adkins, Damek V Spacek, Aaron M Feliciano and Thomas R King
    Citation: BMC Research Notes 2013 6:189
  12. The aim of this study was to explore the predictive value of baseline characteristics in relation to changes in physical activity (PA) and sedentary behaviour among diabetic and pre-diabetic patients participa...

    Authors: Judith HM Helmink, Jessica S Gubbels, Femke N van Brussel-Visser, Nanne K de Vries and Stef PJ Kremers
    Citation: BMC Research Notes 2013 6:190
  13. Manuka honey originates from the manuka tree (Leptospermum scoparium) and its antimicrobial effect has been attributed to a property referred to as Unique Manuka Factor that is absent in other types of honey. Ant...

    Authors: Eric N Hammond and Eric S Donkor
    Citation: BMC Research Notes 2013 6:188
  14. In HIV-infected persons, good adherence to antiretroviral therapy (ART) is essential for successful treatment outcomes. Patients’ worries before starting ART may affect their ART adherence and treatment outcomes.

    Authors: Billy N Mayanja, Kenneth Ekoru, Harriet Namugenyi, Rosemary Lubega and Joseph O Mugisha
    Citation: BMC Research Notes 2013 6:187
  15. The PCR-based detection of archaea DNA in human specimens relies on efficient DNA extraction. We previously designed one such protocol involving only manual steps. In an effort to reduce the workload involved,...

    Authors: Saber Khelaifia, Pierre-Yves Ramonet, Marielle Bedotto Buffet and Michel Drancourt
    Citation: BMC Research Notes 2013 6:186
  16. From a health service perspective, society, with its limited resources, needs to be reassured that evidence-based medicine is also effective when carried out in the frame of ordinary clinical practice. The eff...

    Authors: Siv Grødal Eppeland, Andreas P Diamantopoulos, Dag Magnar Soldal and Glenn Haugeberg
    Citation: BMC Research Notes 2013 6:185
  17. Tranexamic acid (TXA) is an antifibrinolytic drug used as a blood-sparing technique in many surgical specialties. The principal objective of our meta-analysis was to review randomized, controlled trials (RCT) ...

    Authors: Rajiv Gandhi, Heather MK Evans, Safiyyah R Mahomed and Nizar N Mahomed
    Citation: BMC Research Notes 2013 6:184
  18. In patients with schizophrenia, altered brain activation and motor activity levels are central features, reflecting cognitive impairments and negative symptoms, respectively. Newer studies using nonlinear meth...

    Authors: Jan Øystein Berle, Else-Marie Løberg and Ole Bernt Fasmer
    Citation: BMC Research Notes 2013 6:182

    The Erratum to this article has been published in BMC Research Notes 2013 6:332

  19. Body packing is used for international drug transport, immediate drug concealment during a police searching or introducing drugs inside prisons. Despite the high level of specialization of dealers who have sta...

    Authors: Fabio Fernandes Neves, Palmira Cupo, Valdair Francisco Muglia, Jorge Elias Junior, Marcello Henrique Nogueira-Barbosa and Antonio Pazin-Filho
    Citation: BMC Research Notes 2013 6:178
  20. When novel influenza viruses cause human infections, it is critical to characterize the illnesses, viruses, and immune responses to infection in order to develop diagnostics, treatments, and vaccines. The obje...

    Authors: Wendy A Keitel, Pedro A Piedra, Robert L Atmar, Gail Demmler, Hana M El Sahly, Jill Barrett, Rebecca A Halpin, Rosanna Lagos, Susan Fisher-Hoch and Flor Munoz
    Citation: BMC Research Notes 2013 6:177
  21. Global shortage of donor corneas greatly restricts the numbers of corneal transplantations performed yearly. Limited ex vivo expansion of primary human corneal endothelial cells is possible, and a considerable cl...

    Authors: Gary SL Peh, Kah-Peng Toh, Heng-Pei Ang, Xin-Yi Seah, Benjamin L George and Jodhbir S Mehta
    Citation: BMC Research Notes 2013 6:176
  22. Low-stringency single specific primer PCR (LSSP-PCR) is a highly sensitive and discriminating technique that has been extensively used to genetically characterize Trypanosoma cruzi populations in the presence of ...

    Authors: Marcela Segatto, Claudiney Melquíades Rodrigues, Carlos Renato Machado, Glória Regina Franco, Sérgio Danilo Junho Pena and Andréa Mara Macedo
    Citation: BMC Research Notes 2013 6:174
  23. Variations in racial haemoglobin had been previously described in multiple studies locally and abroad. This study was conducted to quantify the differences in haemoglobin of booking primigravidae amongst the t...

    Authors: Albert Chao Chiet Tan, Eugene Weng Kong Leong, Ai Chen Chua and Foong Ming Moy
    Citation: BMC Research Notes 2013 6:173
  24. Although epidemiologic and socioeconomic criteria and biomedical risk factors indicate high-priority for tuberculosis (TB) control in Mexico, molecular epidemiology studies of the disease in the country are sc...

    Authors: Estela López-Rocha, Julio Juárez-Álvarez, Lina Riego-Ruiz, Leonor Enciso-Moreno, Francisco Ortega-Aguilar, Julián Hernández-Nieto, José A Enciso-Moreno and Rubén López-Revilla
    Citation: BMC Research Notes 2013 6:172
  25. The aim of this study was evaluate the late-onset repercussions of heart alterations of patients with systemic lupus erythematosus (SLE) after a 13-year follow up.

    Authors: Moacir Fernandes de Godoy, Cibele Matsuura de Oliveira, Vanessa Alves Fabri, Luiz Carlos de Abreu, Vitor E Valenti, Adilson Casemiro Pires, Rodrigo Daminello Raimundo, José Luiz Figueiredo and Glauce Rejane Leonardi Bertazzi
    Citation: BMC Research Notes 2013 6:171
  26. With the increased use of cardiac computed tomography (CT), radiation dose remains a major issue, although physicians are trying to reduce the substantial risks associated with use of this diagnostic tool. Thi...

    Authors: Sung Hea Kim, Hyun Joong Kim, Hyun Kyun Ki, Eui Jong Chung, Soon Yong Suh, Seong Woo Han and Kyu Hyung Ryu
    Citation: BMC Research Notes 2013 6:170
  27. Validation of new affordable CD4 T cell measurement technologies is crucial specifically in resource-poor countries for antiretroviral treatment eligibility and immunologic CD4 monitoring of HIV-infected patie...

    Authors: Donato Koyalta, Mohammad-Ali Jenabian, Ngamasra Nadjiouroum, Barou Djouater, Noël Djemadji-Oudjeil, Angélique Ndjoyi-Mbiguino and Laurent Bélec
    Citation: BMC Research Notes 2013 6:169
  28. Germ cell development involves formation of the spermatogenic or oogenic lineages from the bipotential primordial germ cells. Signaling mechanisms in the fetal testis and ovary determine whether germ cells ent...

    Authors: Stephanie I Wakeling, Denise C Miles and Patrick S Western
    Citation: BMC Research Notes 2013 6:168
  29. Testicular cancer is a rare disease. The incidence of testicular cancer in undescended testicles is of 3 to 48 times greater than in the general population. In the developed countries, the existence of undesce...

    Authors: Mohammed Fadl Tazi, Omar Riyach, Mustapha Ahsaini, Youness Ahallal, Abdelhak Khallouk, Mohammed Jamal El Fassi and Moulay Hassan Farih
    Citation: BMC Research Notes 2013 6:166
  30. Hemolytic anemia after mitral valve repair is still an underestimated complication because it is a rare condition and there are few described case reports in the literature. The mechanism responsible for hemol...

    Authors: Catarina Cardoso, Patricia Cachado and Teresa Garcia
    Citation: BMC Research Notes 2013 6:165
  31. Hepatitis B virus (HBV) and hepatitis C virus (HBV) infections accounts for substantial proportions of the world wide liver disease. The two hepatotropic virus share common modes of transmission and their co-i...

    Authors: Habtie Tesfa, Belete Biadgo, Fasika Getachew, Kifle Tegegne, Gizachew Yismaw and Dagnachew Muluye
    Citation: BMC Research Notes 2013 6:164
  32. Cerebral palsy (CP) is a major cause of childhood disability. There are various maternal and neonatal predictors associated with the development of CP, and they are variable across different populations. This ...

    Authors: Hala Abdullahi, Mohamed Satti, Duria A Rayis, Abdulmutalab M Imam and Ishag Adam
    Citation: BMC Research Notes 2013 6:163
  33. It is not clear if behaviour change programmes are more or less effective for weight management in people with high BMIs than for those who are moderately overweight. An earlier service evaluation reported on ...

    Authors: Richard James Stubbs, David Johnathan Brogelli, Jenny Barber, Carolyn Pallister, Stephen Whybrow, Amanda Avery and Jacquie Lavin
    Citation: BMC Research Notes 2013 6:161
  34. The hystricognath rodents of the New World, the Caviomorpha, are a diverse lineage with a long evolutionary history, and their representation in South American fossil record begins with their occurrence in Eoc...

    Authors: Carolina M Voloch, Julio F Vilela, Leticia Loss-Oliveira and Carlos G Schrago
    Citation: BMC Research Notes 2013 6:160
  35. A national study in 2007 revealed that in Pakistan the prevalence of hepatitis B is 2.5% and for hepatitis C it is 5%. Unsafe injections have been identified as one of the reasons for the spread of these infec...

    Authors: Arshad Altaf, Sharaf Ali Shah, Kulsoom Shaikh, Fiona M Constable and Selma Khamassi
    Citation: BMC Research Notes 2013 6:159
  36. Cardiac computed tomography angiography (CTA) is feasible for aortic valve evaluation, but retrospective gated protocols required high radiation doses for aortic valve assessment. A prospectively triggered ada...

    Authors: Ashley M Lee, Jonathan Beaudoin, Wai-Ee Thai, Bryan Wai, Gladwin C Hui, Manavjot S Sidhu, Leif-Christopher Engel, Suhny Abbara, Udo Hoffmann and Brian B Ghoshhajra
    Citation: BMC Research Notes 2013 6:158
  37. Prevalence of non-communicable diseases are a challenging problems among menopausal women specially in a least developed country like Bangladesh, where majority of women suffering from at least one chronic dis...

    Authors: Subrina Jesmin, AM Shahidul Islam, Shamima Akter, Md Majedul Islam, Sayeeda Nusrat Sultana, Naoto Yamaguchi, Osamu Okazaki, Masao Moroi, Michiaki Hiroe, Sosuke Kimura, Tetsu Watanabe, Kawano Saturo and Taro Mizutani
    Citation: BMC Research Notes 2013 6:157
  38. Paraganglioma of the urinary bladder is a rare tumor. Herein we sought to describe a case of locally advanced paraganglioma of the urinary bladder managed by partial cystectomy and extended pelvic lymph node d...

    Authors: Jonathan Beilan, Adrienne Lawton, Julio Hajdenberg and Charles J Rosser
    Citation: BMC Research Notes 2013 6:156
  39. Medical schools frequently experience challenges related to diversity and inclusiveness. The authors conducted this study to assess, from a student body’s perspective, the climate at one medical school with re...

    Authors: Jasmeet S Dhaliwal, Lori A Crane, Morgan A Valley and Steven R Lowenstein
    Citation: BMC Research Notes 2013 6:154

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