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  1. Guidelines recommend an early initiation of aspirin treatment in patients with acute cerebral ischemia. Comparative studies on the best starting dose for initiating aspirin therapy to achieve a rapid antiplate...

    Authors: Saskia H Meves, Horst Neubauer, Ursula Overbeck and Heinz G Endres

    Citation: BMC Research Notes 2011 4:106

    Content type: Research article

    Published on:

  2. Type D personality has been associated in the past with increased cardiovascular mortality among patients with established coronary heart disease. Very few studies have investigated the association of type D p...

    Authors: Dimitrios Tziallas, Michael S Kostapanos, Petros Skapinakis, Haralampos J Milionis, Thanos Athanasiou, Moses S Elisaf and Venetsanos Mavreas

    Citation: BMC Research Notes 2011 4:105

    Content type: Short Report

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  4. Depression and anxiety disorders have a high disease burden and as many as 15% of young people report mental health problems. Binge drinking, which is a particularly harmful way of consuming alcohol, is common...

    Authors: Marie-José Theunissen, Maria Jansen and Anke van Gestel

    Citation: BMC Research Notes 2011 4:100

    Content type: Short Report

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  6. Colletotrichum is one of the most widespread and important genus of plant pathogenic fungi worldwide. Various species of Colletotrichum are the causative agents of anthracnose disease in plants, which is a severe...

    Authors: Bungonsiri Intra, Isada Mungsuntisuk, Takuya Nihira, Yasuhiro Igarashi and Watanalai Panbangred

    Citation: BMC Research Notes 2011 4:98

    Content type: Research article

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  10. Machine learning techniques have been widely applied to biological sequences, e.g. to predict drug resistance in HIV-1 from sequences of drug target proteins and protein functional classes. As deletions and in...

    Authors: Dominik Heider, Jens Verheyen and Daniel Hoffmann

    Citation: BMC Research Notes 2011 4:94

    Content type: Short Report

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  12. The PneuX System is a novel endotracheal tube and tracheal seal monitor, which has been designed to minimise the aspiration of oropharyngeal secretions. We aimed to determine the incidence of ventilator-associ...

    Authors: Alex Doyle, Andrew Fletcher, Joseph Carter, Mark Blunt and Peter Young

    Citation: BMC Research Notes 2011 4:92

    Content type: Short Report

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  15. Rural Australians face a higher mental health and lifestyle disease burden (obesity, diabetes and cardiovascular disease) than their urban counterparts. Our ongoing research reveals that the Australian farming...

    Authors: Susan Brumby, Ananda Chandrasekara, Scott McCoombe, Peter Kremer and Paul Lewandowski

    Citation: BMC Research Notes 2011 4:89

    Content type: Hypothesis

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  16. Atlantic salmon (Salmo salar L.) is an environmentally and economically important organism and its gene content is reasonably well characterized. From a transcriptional standpoint, it is important to characterize...

    Authors: Stuart G Jantzen, Dan S Sanderson, Kris R von Schalburg, Motoshige Yasuike, Francesco Marass and Ben F Koop

    Citation: BMC Research Notes 2011 4:88

    Content type: Data Note

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  17. Amongst the extensive literature on immunohistochemical profile of breast cancer, very little is found on populations exposed to a potential risk factor such as depleted uranium. This study looked at the immun...

    Authors: Mais M Al-Mumen, Asad A Al-Janabi, Alaa S Jumaa, Kaswer M Al-Toriahi and Akeel A Yasseen

    Citation: BMC Research Notes 2011 4:87

    Content type: Project Note

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  18. Proteomic techniques allow researchers to perform detailed analyses of cellular states and many studies are published each year, which highlight large numbers of proteins quantified in different samples. Howev...

    Authors: Jenna Kenyani, J Alberto Medina-Aunon, Salvador Martinez-Bartolomé, Juan-Pablo Albar, Jonathan M Wastling and Andrew R Jones

    Citation: BMC Research Notes 2011 4:86

    Content type: Data Note

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  19. Secondary metabolites are reported to interfere with the isolation of RNA particularly with the recipes that use guanidinium-based salt. Such interference was observed in isolation of RNA with medicinal plants...

    Authors: Sanjay Ghawana, Asosii Paul, Hitesh Kumar, Arun Kumar, Harsharan Singh, Pardeep K Bhardwaj, Arti Rani, Ravi S Singh, Jyoti Raizada, Kashmir Singh and Sanjay Kumar

    Citation: BMC Research Notes 2011 4:85

    Content type: Technical Note

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  20. The accurate determination of the number of copies of a gene in the genome (gene dosage) is essential for a number of genetic analyses. Quantitative real time PCR (qPCR) with TaqMan detection has shown advanta...

    Authors: Yolanda Bel, Juan Ferré and Baltasar Escriche

    Citation: BMC Research Notes 2011 4:84

    Content type: Short Report

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  21. A high quality of timely delivered medical appraisals is crucial for social and other insurances to judge possible occupational reintegration measures for patients with medical conditions who are in danger to ...

    Authors: Klaus Eichler, Daniel Imhof, Yvonne Bollag, Susanna Stöhr, Niklaus Gyr and Holger Auerbach

    Citation: BMC Research Notes 2011 4:83

    Content type: Short Report

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  22. Unisexual vertebrates have been demonstrated to reproduce by gynogenesis, hybridogenesis, parthenogenesis, or kleptogenesis, however, it is uncertain how the reproduction mode contributes to the clonal diversi...

    Authors: Zhong-Wei Wang, Hua-Ping Zhu, Da Wang, Fang-Fang Jiang, Wei Guo, Li Zhou and Jian-Fang Gui

    Citation: BMC Research Notes 2011 4:82

    Content type: Research article

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  23. The West Sumatra earthquake that occurred on September 30, 2009, caused severe damage in some districts, including Padang Pariaman. As Padang Pariaman is an earthquake-prone area, disaster and emergency manage...

    Authors: Ahmad Fuady, Trevino A Pakasi and Muchtaruddin Mansyur

    Citation: BMC Research Notes 2011 4:81

    Content type: Short Report

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  24. Pyogenic hepatic abscesses are relatively rare, though untreated are uniformly fatal. A recent paradigm shift in the management of liver abscesses, facilitated by advances in diagnostic and interventional radi...

    Authors: Helen M Heneghan, Nuala A Healy, Sean T Martin, Ronan S Ryan, Niamh Nolan, Oscar Traynor and Ronan Waldron

    Citation: BMC Research Notes 2011 4:80

    Content type: Research article

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  26. The present study represents a genome-wide transcriptomic analysis of the response of the model streptomycete Streptomyces coelicolor A3(2) M145 to fermentor culture in Modified Evans Media limited, respectively,...

    Authors: Richard A Lewis, Sanjay K Shahi, Emma Laing, Giselda Bucca, Georgios Efthimiou, Michael Bushell and Colin P Smith

    Citation: BMC Research Notes 2011 4:78

    Content type: Short Report

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  27. Clostridium difficile is the major cause of pseudomembranous colitis associated with antibiotic use, and the spread of the hypervirulent epidemic ribotype 027/NAP-1 strain across hospitals worldwide has re-focuse...

    Authors: Li-Yang Hsu, Thean Yen Tan, Tse Hsien Koh, Andrea L Kwa, Prabha Krishnan, Nancy W Tee and Roland Jureen

    Citation: BMC Research Notes 2011 4:77

    Content type: Short Report

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  29. Research undertaken in developing countries has assessed discrepancies in police reporting of Road Traffic Injury (RTI) for urban settings only. The objective of this study was to assess differences in RTI rep...

    Authors: Junaid A Bhatti, Junaid A Razzak, Emmanuel Lagarde and Louis-Rachid Salmi

    Citation: BMC Research Notes 2011 4:75

    Content type: Research article

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  30. Candida species including Candida krusei have become common pathogens, especially in immune-compromised patients. Pellicle on the surface of incubating nutrient broth extending with an adherent film above the bro...

    Authors: Jacob Fleischmann and Elia M Sripuntanagoon

    Citation: BMC Research Notes 2011 4:74

    Content type: Short Report

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  31. Two general approaches to prokaryotic live-cell imaging have been employed to date, growing bacteria on thin agar pads or growing bacteria in micro-channels. The methods using agar pads 'sandwich' the cells be...

    Authors: Graham Joyce, Brian D Robertson and Kerstin J Williams

    Citation: BMC Research Notes 2011 4:73

    Content type: Technical Note

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  32. Single Nucleotide Polymorphisms (SNPs) in intron 2 of the Fibroblast Growth Factor Receptor Type 2 (FGFR2) gene, including rs2981582, contribute to multifactorial breast cancer susceptibility. The high risk polym...

    Authors: Amy J Martin, Andrew Grant, Alison M Ashfield, Colin N Palmer, Lee Baker, Philip R Quinlan, Colin A Purdie, Alastair M Thompson, Lee B Jordan and Jonathan N Berg

    Citation: BMC Research Notes 2011 4:72

    Content type: Short Report

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  33. Both low birth weight, an indicator of intrauterine growth restriction, and low grade systemic inflammation depicted by high sensitivity C-reactive protein (hs-CRP) have emerged as independent predictors of ca...

    Authors: Azad R Bhuiyan, Sathanur R Srinivasan, Wei Chen, Mario J Azevedo and Gerald S Berenson

    Citation: BMC Research Notes 2011 4:71

    Content type: Short Report

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  35. Laser capture microdissection (LCM) can be applied to tissues where cells of interest are distinguishable from surrounding cell populations. Here, we have optimized LCM for fresh frozen normal breast tissue wh...

    Authors: Kristina E Aaltonen, Anna Ebbesson, Caroline Wigerup and Ingrid Hedenfalk

    Citation: BMC Research Notes 2011 4:69

    Content type: Technical Note

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  36. Although the etiology of preeclampsia is still unclear, recent work suggests that changes in circulating angiogenic factors play a key role in its pathogenesis. In the trophoblast of women with preeclampsia, h...

    Authors: Sonia Nava-Salazar, Elly N Sánchez-Rodríguez, C Adriana Mendoza-Rodríguez, Carlos Moran, Juan F Romero-Arauz and Marco A Cerbón

    Citation: BMC Research Notes 2011 4:68

    Content type: Research article

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  37. Etlingera elatior or 'pink torch ginger' (Zingiberaceae) are widely cultivated in tropical countries and used as spices and food flavoring. The purpose of this study was to evaluate the antioxidant effects of Etl...

    Authors: Tan Jackie, Nagaraja Haleagrahara and Srikumar Chakravarthi

    Citation: BMC Research Notes 2011 4:67

    Content type: Short Report

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  38. 5-Aminolevulinic acid (ALA) is a precursor of heme that is fundamentally important in aerobic energy metabolism. Among the enzymes involved in aerobic energy metabolism, cytochrome c oxidase (COX) is crucial. In ...

    Authors: Shun-ichiro Ogura, Kouji Maruyama, Yuichiro Hagiya, Yuta Sugiyama, Kyoko Tsuchiya, Kiwamu Takahashi, Fuminori Abe, Kenji Tabata, Ichiro Okura, Motowo Nakajima and Tohru Tanaka

    Citation: BMC Research Notes 2011 4:66

    Content type: Short Report

    Published on:

  39. The lack of a sufficient number of molecular markers seriously limits the cognition of genetic relationships within and between populations of many species. Likewise, the genetic diversity of domestic goose (Anse...

    Authors: Krzysztof Andres and Ewa Kapkowska

    Citation: BMC Research Notes 2011 4:65

    Content type: Short Report

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  40. Herpes simplex virus type 2 (HSV-2) is the most frequent cause of genital ulcer disease worldwide and has been associated with increased risk for HIV-1 acquisition and transmission. We conducted a cross-sectio...

    Authors: Andrew Mujugira, Amalia S Magaret, Jared M Baeten, Connie Celum and Jairam Lingappa

    Citation: BMC Research Notes 2011 4:64

    Content type: Research article

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  41. This short communication focuses the on articular cartilage and the subchondral bone, both of which play important roles in the development of osteoarthritis (OA). There are indications that estrogen-deficienc...

    Authors: Anne C Bay-Jensen, Rasmus H Nielsen, Toni Segovia-Silvestre, Moïse Azria, Frank Staedtler, Martin Letzkus, Nicole Hartmann, Arndt H Brachat and Morten A Karsdal

    Citation: BMC Research Notes 2011 4:63

    Content type: Short Report

    Published on:

  42. Aboriginal people in Australia experience higher mortality from cancer compared with non-Aboriginal Australians, despite an overall lower incidence. A notable contributor to this disparity is that many Aborigi...

    Authors: Sandra C Thompson, Shaouli Shahid, Dawn Bessarab, Angela Durey and Patricia M Davidson

    Citation: BMC Research Notes 2011 4:62

    Content type: Short Report

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  43. The H1N1 influenza pandemic had garnered a large amount of attention. Currently, the most effective preventive measure available is the H1N1 vaccine. We aimed to assess the willingness of our study participant...

    Authors: Gasmelseed Y Ahmed, Hanan H Balkhy, Saleh Bafaqeer, Badr Al-Jasir and Abdulhakeem Althaqafi

    Citation: BMC Research Notes 2011 4:61

    Content type: Short Report

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  44. There has been increased interest in the study of molecular survival mechanisms expressed by foodborne pathogens present on food surfaces. Determining genomic responses of these pathogens to antimicrobials is ...

    Authors: Sujata A Sirsat, Arunachalam Muthaiyan and Steven C Ricke

    Citation: BMC Research Notes 2011 4:60

    Content type: Short Report

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  45. Worldwide, the genus Haliotis is represented by 56 extant species and several of these are commercially cultured. Among the six abalone species found in South Africa, Haliotis midae is the only aquacultured speci...

    Authors: Paolo Franchini, Mathilde van der Merwe and Rouvay Roodt-Wilding

    Citation: BMC Research Notes 2011 4:59

    Content type: Research article

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  46. This article aims to update the existing systematic review evidence elicited by Mickenautsch et al. up to 18 January 2008 (published in the European Journal of Paediatric Dentistry in 2009) and addressing the ...

    Authors: Steffen Mickenautsch and Veerasamy Yengopal

    Citation: BMC Research Notes 2011 4:58

    Content type: Correspondence

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  47. High-throughput biological experiments can produce a large amount of data showing little overlap with current knowledge. This may be a problem when evaluating alternative scoring mechanisms for such data accor...

    Authors: Jean F Fontaine, Bernhard Suter and Miguel A Andrade-Navarro

    Citation: BMC Research Notes 2011 4:57

    Content type: Technical Note

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  48. Carcinoma of unknown primary tumors (CUP) is present in 0.5%-9% of all patients with malignant neoplasms; only 20%-27% of primary sites are identified before the patients die. Currently, 18F-fluorodeoxy-glucos...

    Authors: Jong Sun Park, Jae-Joon Yim, Won Jun Kang, June-Key Chung, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young-Soo Shim and Sang-Min Lee

    Citation: BMC Research Notes 2011 4:56

    Content type: Short Report

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  49. The discovery of patterns in DNA, RNA, and protein sequences has led to the solution of many vital biological problems. For instance, the identification of patterns in nucleic acid sequences has resulted in th...

    Authors: Sanguthevar Rajasekaran and Hieu Dinh

    Citation: BMC Research Notes 2011 4:54

    Content type: Research article

    Published on:

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