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  1. Low temperature is required for the competence of winter wheat to flowering (vernalization), and several key components in the vernalization-mediated flowering pathway have been isolated. A Y2H library is a ve...

    Authors: Shuanghe Cao and Liuling Yan
    Citation: BMC Research Notes 2013 6:81
    Content type: Research article Published on:

  2. Occupational burnout is associated with severe negative health effects. While stress management programs proved to have a positive influence on the well-being of patients suffering from burnout, it remains unc...

    Authors: Markus Gerber, Serge Brand, Catherine Elliot, Edith Holsboer-Trachsler, Uwe Pühse and Johannes Beck
    Citation: BMC Research Notes 2013 6:78
    Content type: Research article Published on:

  3. Invasive fungal infections caused by uncommon fungi have increased in recent years. Hospitalized low-birth-weight infants are at high risk for neonatal fungal infections. Pichia fabianii is a rare pathogen causin...

    Authors: Yuan Wu, Jing Wang, Wenge Li, Hongbin Jia, Jie Che, Jinxing Lu, Lanzheng Liu and Ying Cheng
    Citation: BMC Research Notes 2013 6:77
    Content type: Case Report Published on:

  4. Reverse transcription quantitative PCR has become a powerful technique to monitor mRNA transcription in response to different environmental conditions in many bacterial species. However, correct evaluation of ...

    Authors: Espen Brudal, Hanne Cecilie Winther-Larsen, Duncan John Colquhoun and Samuel Duodu
    Citation: BMC Research Notes 2013 6:76
    Content type: Research article Published on:

  5. The shrimp Nematocarcinus lanceopes Bate, 1888 is found in the deep sea around Antarctica and sub-Antarctic islands. Previous studies on mitochondrial data and species distribution models provided evidence for a ...

    Authors: Johannes Dambach, Michael J Raupach, Christoph Mayer, Julia Schwarzer and Florian Leese
    Citation: BMC Research Notes 2013 6:75
    Content type: Short Report Published on:

  6. Cognitive behavior therapy (CBT) is regarded as an effective treatment for social anxiety disorder (SAD) in Europe and North America. Individual CBT might be acceptable and effective for patients with SAD even...

    Authors: Naoki Yoshinaga, Fumiyo Ohshima, Satoshi Matsuki, Mari Tanaka, Tomomi Kobayashi, Hanae Ibuki, Kenichi Asano, Osamu Kobori, Tetsuya Shiraishi, Emi Ito, Michiko Nakazato, Akiko Nakagawa, Masaomi Iyo and Eiji Shimizu
    Citation: BMC Research Notes 2013 6:74
    Content type: Research article Published on:

  7. This study aimed at enhancing the transcriptomic resources for two sibling species of moths, Ostrinia scapulalis (Adzuki bean borer) and Ostrinia nubilalis (European corn borer), as a foundation for future resear...

    Authors: Bernhard Gschloessl, Emmanuelle Beyne, Philippe Audiot, Denis Bourguet and Réjane Streiff
    Citation: BMC Research Notes 2013 6:73
    Content type: Research article Published on:

  8. Hybridization based assays and capture systems depend on the specificity of hybridization between a probe and its intended target. A common guideline in the construction of DNA microarrays, for instance, is th...

    Authors: Jaishree Garhyan, Raad Z Gharaibeh, Stephen McGee and Cynthia J Gibas
    Citation: BMC Research Notes 2013 6:72
    Content type: Research article Published on:

  10. The aim of this study was to develop liver tissue preparation suitable for investigating toxins. Hepatocyte respiration, ATP content, urea synthesis, caspase activity and morphology were measured as a function...

    Authors: Ali S Alfazari, Bayan Al-Dabbagh, Saeeda Almarzooqi, Alia Albawardi and Abdul-Kader Souid
    Citation: BMC Research Notes 2013 6:70
    Content type: Technical Note Published on:

  11. The reporting and interpretation of data from clinical trials of proximal humeral fractures are hampered by the use of two partly incommensurable fracture classification systems: the Neer classification and th...

    Authors: Stig Brorson, Henrik Eckardt, Laurent Audigé, Bernd Rolauffs and Christian Bahrs
    Citation: BMC Research Notes 2013 6:69
    Content type: Research article Published on:

  13. Considering the current high consumption of energy drinks, the aim of the present study is to evaluate the influence of energy drinks in removing the smear layer and exposing dentinal tubules on root surface.

    Authors: Shelon CS Pinto, Matheus C Bandeca, Carolina N Silva, Rodrigo Cavassim, Alvaro H Borges and José E C Sampaio
    Citation: BMC Research Notes 2013 6:67
    Content type: Research article Published on:

  15. Vancomycin is the primary treatment for infections caused by methicilin-resistant Staphylococcus aureus (MRSA). The association of vancomycin treatment failures with increased vancomycin minimum inhibitory con...

    Authors: Silvestre Joana, Póvoa Pedro, Gonçalves Elsa and Martins Filomena
    Citation: BMC Research Notes 2013 6:65
    Content type: Research article Published on:

  17. Operative management of all gunshot’s traumas carries a high rate of unwarranted interventions that are known to cause serious complications. Selective nonoperative management is thus being increasingly practi...

    Authors: Muhammad Sohaib Khan, Bilal Masood Khan, Sumbul Naz and Muhammad Taqi Pirzada
    Citation: BMC Research Notes 2013 6:63
    Content type: Case Report Published on:

  18. During pregnancy women are at increased risk of severe complications to influenza infection, including death of mother or fetus, especially if chronic comorbid medical conditions such as diabetes mellitus are ...

    Authors: Kristine Madsen, Ditte Gry Strange, Morten Hedegaard, Elisabeth R Mathiesen and Peter Damm
    Citation: BMC Research Notes 2013 6:62
    Content type: Case Report Published on:

  19. There is a high prevalence of depression in individuals with type 2 diabetes mellitus. Depressive disorders are associated with increased medical morbidity and mortality in individuals with diabetes. It has be...

    Authors: Adriana Alvarez, Jose Faccioli, Mónica Guinzbourg, María M Castex, Claudia Bayón, Walter Masson, Ignacio Bluro, Andrea Kozak, Patricia Sorroche, Lina Capurro, Luis Grosembacher, Adrián Proietti, Carlos Finkelsztein, Lucas Costa, Patricia Fainstein Day, Arturo Cagide…
    Citation: BMC Research Notes 2013 6:61
    Content type: Research article Published on:

  20. A valid, accurate method for determining gestational age (GA) is crucial in classifying early and late prematurity, and it is a relevant issue in perinatology. This study aimed at assessing the validity of dif...

    Authors: Ana Paula Esteves Pereira, Marcos Augusto Bastos Dias, Maria Helena Bastos, Nogueira granado Nogueira da Gama and Maria do Carmo Leal
    Citation: BMC Research Notes 2013 6:60
    Content type: Research article Published on:

  21. Yoga exercises are known to decrease stress and restore autonomic balance. Yet knowledge about the physiological effects of inversion postures is limited. This study aimed to investigate the effects of inversi...

    Authors: Marian E Papp, Petra Lindfors, Niklas Storck and Per E Wändell
    Citation: BMC Research Notes 2013 6:59
    Content type: Research article Published on:

  22. Accurate measurements of spinal movement require reliable determination of anatomical landmarks. Current methods of identifying these are not sufficiently reliable or valid for this purpose. A reliable and con...

    Authors: Markus J Ernst, Fabian M Rast, Christoph M Bauer, Valentine L Marcar and Jan Kool
    Citation: BMC Research Notes 2013 6:58
    Content type: Technical Note Published on:

  24. As an in vitro model porcine peripheral blood mononuclear cells (PBMCs) is frequently used as for immunogenetic research with the stimulation of bacterial antigens. To investigate the immunocompetence of PBMCs fo...

    Authors: Mehmet Ulas Cinar, Mohammad Ariful Islam, Maren Pröll, Hakan Kocamis, Ernst Tholen, Dawit Tesfaye, Christian Looft, Karl Schellander and Muhammad Jasim Uddin
    Citation: BMC Research Notes 2013 6:56
    Content type: Research article Published on:

  25. Paratuberculosis remains today a major global problem in animal health, especially for dairy cattle. However, the diagnosis of its etiologic agent, Mycobacterium avium subsp. paratuberculosis (Map), still lacks s...

    Authors: Louise H Lefrancois, Christelle C Bodier, Sophie Lecher, Florence B Gilbert, Thierry Cochard, Grégoire Harichaux, Valérie Labas, Ana Paula Teixeira-Gomes, Dominique Raze, Camille Locht and Franck Biet
    Citation: BMC Research Notes 2013 6:55
    Content type: Technical Note Published on:

  26. Innate immune system is the first line of research when studying immune response to diverse infections and autoimmune/inflammatory diseases. This immune response has been reported to be genetically diverse, du...

    Authors: Lisa M Esteves, Sara M Bulhões, Maria J Brilhante and Luisa Mota-Vieira
    Citation: BMC Research Notes 2013 6:54
    Content type: Technical Note Published on:

  28. Lifestyle modifications including exercise are beneficial and fundamentally part of the therapy of metabolic syndrome, although in most of the cases medical interventions are also required to reach the target ...

    Authors: Andrea László, László Kalabay and János Nemcsik
    Citation: BMC Research Notes 2013 6:52
    Content type: Case Report Published on:

  29. Uridine diphosphate-glucuronosyltransferase (UGT) gene family is involved in the detoxification of biomaterials and drugs in the liver. Among the UGT gene family members, only UGT1A1 is involved in bilirubin c...

    Authors: Akimune Kaga, Yukimune Ohkubo, Yohei Watanabe, Sachiko Saito, Takuma Matsuki, Haruo Usuda, Susumu Kanda, Yutaka Suzuki, Muneyuki Tanabu and Shigeo Kure
    Citation: BMC Research Notes 2013 6:51
    Content type: Case Report Published on:

  30. Obesity among fertile women is a global problem. 25% of pregnant Swedish women are overweight at admission to the antenatal clinic and 12% of them are considered as obese. Previous studies have shown an increa...

    Authors: Rebecka Kaplan-Sturk, Helena Åkerud, Helena Volgsten, Lena Hellström-Westas and Eva Wiberg-Itzel
    Citation: BMC Research Notes 2013 6:50
    Content type: Research article Published on:

  31. The current ‘gold standard’ for serotyping pneumococci is the Quellung test. This technique is laborious and requires a certain level of training to correctly perform. Commercial pneumococcal latex agglutinati...

    Authors: Belinda D Ortika, Maha Habib, Eileen M Dunne, Barbara D Porter and Catherine Satzke
    Citation: BMC Research Notes 2013 6:49
    Content type: Research article Published on:

  32. Colonoscopes are designed with balance between flexibility, required to negotiate angulations, and stiffness, required to counteract the propensity for looping in unfixed sections of the colon, which retards a...

    Authors: Jeffrey M East
    Citation: BMC Research Notes 2013 6:48
    Content type: Research article Published on:

  33. Sugarcane is an important cash crop, providing 70% of the global raw sugar as well as raw material for biofuel production. Genetic analysis is hindered in sugarcane because of its large and complex polyploid g...

    Authors: Amaresh Chandra, Radha Jain, Sushil Solomon, Shiksha Shrivastava and Ajoy K Roy
    Citation: BMC Research Notes 2013 6:47
    Content type: Short Report Published on:

  34. The use of quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR) has become widely applied as a method to measure transcript abundance. In order to be reflective of biological proces...

    Authors: Ruoxin Wei, Elizabeth Anne Stewart and Winfried M Amoaku
    Citation: BMC Research Notes 2013 6:46
    Content type: Research article Published on:

  35. Cytomegalovirus infection of the gastrointestinal tract is common and is more often seen in patients with acquired immunodeficiency syndrome (AIDS). Although small bowel infection is less common than infection...

    Authors: Nick Michalopoulos, Konstantina Triantafillopoulou, Eleni Beretouli, Styliani Laskou, Theodossis S Papavramidis, Ioannis Pliakos, Prodromos Hytiroglou and Spiros T Papavramidis
    Citation: BMC Research Notes 2013 6:45
    Content type: Case Report Published on:

  36. Chlamydia trachomatis is one of the major causes of sexually transmitted infections throughout the world. Most infections are asymptomatic and remain undetected. Burden of disease in the Kenyan population is not ...

    Authors: Ruchika Kohli, Walter P Konya, Timona Obura, William Stones and Gunturu Revathi
    Citation: BMC Research Notes 2013 6:44
    Content type: Short Report Published on:

  37. We performed a Nimblegen intra-platform microarray comparison by assessing two categories of flax target probes (short 25-mers oligonucleotides and long 60-mers oligonucleotides) in identical conditions of tar...

    Authors: Stephane Fenart, Malika Chabi, Sophie Gallina, Rudy Huis, Godfrey Neutelings, Nathalie Riviere, Brigitte Thomasset, Simon Hawkins and Anca Lucau-Danila
    Citation: BMC Research Notes 2013 6:43
    Content type: Research article Published on:

  38. Intussusception is one of the less common causes of intestinal obstruction among adults. It is usually covert (concealed) in its clinical presentation. The ileo-colic type with accompanying anal protrusion is ...

    Authors: Peter A Ongom, Robert L Lukande and Josephat Jombwe
    Citation: BMC Research Notes 2013 6:42
    Content type: Case Report Published on:

  39. Medical research productivity reflects the level of medical education and practice in a particular country. The objective of this study was to examine the quantity and quality of medical and biomedical researc...

    Authors: Waleed M Sweileh, Sa’ed H Zyoud, Ansam F Sawalha, Adham Abu-Taha, Ayman Hussein and Samah W Al-Jabi
    Citation: BMC Research Notes 2013 6:41
    Content type: Short Report Published on:

  41. The V-ATPase is a proton pump that creates an acidic medium, necessary for lysosome function and vesicular traffic. It is also essential for several developmental processes. Many enzymes, like the V-ATPase, ar...

    Authors: Jose L Ramos-Balderas, Samantha Carrillo-Rosas, Aida Guzman, Rosa E Navarro and Ernesto Maldonado
    Citation: BMC Research Notes 2013 6:39
    Content type: Short Report Published on:

  43. Patient reported outcomes are accepted as important outcome measures in rheumatology. The fluctuating symptoms in patients with rheumatic diseases have serious implications for sample size in clinical trials. ...

    Authors: Geir Smedslund, Heidi Andersen Zangi, Petter Mowinckel and Kåre Birger Hagen
    Citation: BMC Research Notes 2013 6:37
    Content type: Short Report Published on:

  44. Obsessive compulsive disorders are a complex group that can have a variety of manifestations. Many authors now describe an obsessive compulsive spectrum disorder where many other specific diagnostic entities s...

    Authors: Chaturaka Rodrigo, Thushani Henegama and Raveen Hanwella
    Citation: BMC Research Notes 2013 6:36
    Content type: Case Report Published on:

  46. Accurate measurements of mRNA expression levels in tissues or cells are crucially dependent on the use of relevant reference genes for normalization of data. In this study we used quantitative real-time PCR an...

    Authors: Annika Lindqvist, Dustin Manders and R Ann Word
    Citation: BMC Research Notes 2013 6:34
    Content type: Research article Published on:

  47. Formalin fixed, paraffin embedded tissues are most commonly used for routine pathology analysis and for long term tissue preservation in the clinical setting. Many institutions have large archives of Formalin ...

    Authors: Douglas W Mahoney, Terry M Therneau, S Keith Anderson, Jin Jen, Jean-Pierre A Kocher, Monica M Reinholz, Edith A Perez and Jeanette E Eckel-Passow
    Citation: BMC Research Notes 2013 6:33
    Content type: Technical Note Published on:

  48. Cardioembolic stroke is an under-recognized complication in patients with limb-girdle muscular dystrophy 1B. Here we present a young stroke patient who had a novel lamin A/C gene (LMNA) mutation.

    Authors: Chih-Hao Chen, Sung-Chun Tang, Yi-Ning Su, Chih-Chao Yang and Jiann-Shing Jeng
    Citation: BMC Research Notes 2013 6:32
    Content type: Case Report Published on:

  50. Melanoacanthoma (MA) has been described in the oral mucosa as a solitary lesion or, occasionally, as multiple lesions. MA mainly affects dark skinned patients and grows rapidly, showing a plane or slightly rai...

    Authors: Luis Felipe das Chagas e Silva de Carvalho, Vitor Hugo Farina, Luiz Antonio Guimarães Cabral, Adriana Aigotti Haberbeck Brandão, Ricardo Della Coletta and Janete Dias Almeida
    Citation: BMC Research Notes 2013 6:30
    Content type: Case Report Published on:
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