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  1. In 2018, we conducted a retrospective survey using the medical records of 484 patients with type 2 diabetes. The observed value of coronary heart disease (CHD) incidence after 5 years and the predicted value b...

    Authors: Yasunari Yamashita, Rina Kitajima, Kiyoshi Matsubara, Gaku Inoue and Hajime Matsubara

    Citation: BMC Research Notes 2021 14:92

    Content type: Research note

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  2. Prompt diagnosis of Helicobacter pylori infection is essential for proper treatment and eradication of the pathogen because prolonged infection could lead to gastric cancer. Sensitive and cost effective diagnosti...

    Authors: A. Ajayi, T. Jolaiya and S. I. Smith

    Citation: BMC Research Notes 2021 14:90

    Content type: Research note

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  3. Tuberculosis (TB) is a major cause of morbidity and mortality globally. Despite efforts to eliminate TB in Thailand, the incidence rate has declined slowly. This study aimed to identify the incidence and risk ...

    Authors: Sakarn Charoensakulchai, Chaiyapun Lertpheantum, Chanapon Aksornpusitpong, Peeranut Trakulsuk, Boonsub Sakboonyarat, Ram Rangsin, Mathirut Mungthin and Phunlerd Piyaraj

    Citation: BMC Research Notes 2021 14:89

    Content type: Research note

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  4. Nosocomial infections (NIs) are known as one of the remarkable problems in all countries. This study is aimed to estimate the prevalence rate of nosocomial bacterial agents with antimicrobial susceptibility pa...

    Authors: Hamid Sadeghi, Saeideh Gholamzadeh Khoei, Mehdi Bakht, Mohammad Rostamani, Sara Rahimi, Mehdi Ghaemi and Bahman Mirzaei

    Citation: BMC Research Notes 2021 14:88

    Content type: Research note

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  5. The most common histopathologic malignant and benign nodules are Adenocarcinoma and Granuloma, respectively, which have different standards of care. In this paper, we propose an automatic framework for the dia...

    Authors: Mahsa Bank Tavakoli, Mahdi Orooji, Mehdi Teimouri and Ramita Shahabifar

    Citation: BMC Research Notes 2021 14:87

    Content type: Research note

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  6. To assess the appropriateness of the statistical methodology used in a recent meta-analysis investigating the effect of maternity waiting homes (MWHs) on perinatal mortality in Sub-Saharan Africa.

    Authors: Jaameeta Kurji, Kristy Hackett, Kayli Wild and Zohra Lassi

    Citation: BMC Research Notes 2021 14:86

    Content type: Research note

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  7. The purpose of this study was to compare the charges and payments associated with bone marrow aspiration and biopsies performed by hematology/oncology specialists versus interventional radiology specialists at...

    Authors: Nancy W. Bethuel, Eric Bravin, Nicole Krupa, Paul Jenkins, Melissa Scribani and Anne Gadomski

    Citation: BMC Research Notes 2021 14:84

    Content type: Research note

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  8. The nosocomial pathogen, Acinetobacter baumannii, has acquired clinical significance due to its ability to persist in hospital settings and survive antibiotic treatment, which eventually resulted in the rapid spr...

    Authors: Kah Ern Ten, Muhammad Zarul Hanifah Md Zoqratt, Qasim Ayub and Hock Siew Tan

    Citation: BMC Research Notes 2021 14:83

    Content type: Research note

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  9. Necrotizing enterocolitis (NEC) is the most frequent life-threatening gastrointestinal disease experienced by premature infants in neonatal intensive care units all over the world. The objective of the present...

    Authors: Éric Tremblay, Emanuela Ferretti, Corentin Babakissa, Karolina Maria Burghardt, Emile Levy and Jean-François Beaulieu

    Citation: BMC Research Notes 2021 14:82

    Content type: Research note

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  10. We developed a silver-containing hydroxyapatite (Ag-HA) coating to prevent periprosthetic joint infection (PJI). Methicillin-resistant Staphylococcus aureus (MRSA) is the main PJI-causing bacteria. Previously, we...

    Authors: Akira Hashimoto, Hiroshi Miyamoto, Sakumo Kii, Tomoki Kobatake, Takeo Shobuike, Iwao Noda, Motoki Sonohata and Masaaki Mawatari

    Citation: BMC Research Notes 2021 14:81

    Content type: Research note

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  11. Non-haem iron(II)- and 2-oxoglutarate-dependent dioxygenases (i2OGdd), are a taxonomically and functionally diverse group of enzymes. The active site comprises ferrous iron in a hexa-coordinated distorted octa...

    Authors: Siddhartha Kundu

    Citation: BMC Research Notes 2021 14:80

    Content type: Research note

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  12. Brucellosis is a zoonosis almost chronic disease. Brucellosis bacteria can remain in the environment for a long time. Thus, climate irregularities could pave the way for the survival of the bacterium brucellos...

    Authors: Maryam Mohammadian-Khoshnoud, Majid Sadeghifar, Zahra Cheraghi and Zahra Hosseinkhani

    Citation: BMC Research Notes 2021 14:79

    Content type: Research note

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  13. Small angle X-ray scattering (SAXS) analysis is a sensitive way of determining the ultrastructure of collagen in tissues. Little is known about how parameters measured by SAXS are affected by preservatives com...

    Authors: Susyn Joan Kelly, Lizette duPlessis, John Soley, Frazer Noble, Hannah Carolyn Wells and Patrick John Kelly

    Citation: BMC Research Notes 2021 14:78

    Content type: Research note

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  14. The objective of this study was to determine the proportion of extended spectrum β-lactamase producing gram-negative bacteria (ESBL-GNB) colonizing patients admitted at Mazimbu hospital and Morogoro Regional h...

    Authors: Nyambura Moremi, Vitus Silago, Erick G. Mselewa, Ashery P. Chifwaguzi, Mariam M. Mirambo, Martha F. Mushi, Lucas Matemba, Jeremiah Seni and Stephen E. Mshana

    Citation: BMC Research Notes 2021 14:77

    Content type: Research note

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  15. Hospitalized patients who presented within the last 24 h with a bacterial infection were recruited. Participants were assigned into sepsis and uncomplicated infection groups. In addition, healthy volunteers we...

    Authors: Velma Herwanto, Benjamin Tang, Ya Wang, Maryam Shojaei, Marek Nalos, Amith Shetty, Kevin Lai, Anthony S. McLean and Klaus Schughart

    Citation: BMC Research Notes 2021 14:76

    Content type: Data note

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  16. Development of sequencing technology has opened up vast opportunities for tree genomic research in the tropics. One of the aforesaid technologies named ONT (Oxford Nanopore Technology) has attracted researcher...

    Authors: Iskandar Zulkarnaen Siregar, Fifi Gus Dwiyanti, Rahadian Pratama, Deden Derajat Matra and Muhammad Majiidu

    Citation: BMC Research Notes 2021 14:75

    Content type: Data note

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  17. The major purpose of this study was to determine the specific muscle(s) for superior sprint performance in sprinters. The cross sectional areas (CSAs) of ten muscles of the trunk and lower limb were measured u...

    Authors: Nobuaki Tottori, Tadashi Suga, Yuto Miyake, Ryo Tsuchikane, Takahiro Tanaka, Masafumi Terada, Mitsuo Otsuka, Akinori Nagano, Satoshi Fujita and Tadao Isaka

    Citation: BMC Research Notes 2021 14:74

    Content type: Research note

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  18. The use of agarose in nucleic acid electrophoresis is the gold standard. However, agarose is very expensive and not readily available in resource limited developing countries like Ghana. Hence, finding a more ...

    Authors: Francis Tanam Djankpa, Gideon Akuamoah Wiafe, Bernard Ntim Boateng, Korantema Mawuena Tsegah, Samuel Essien-Baidoo, Mark Bilinyi Ulanja, Kwame Ofori Affram, Abdala Mumuni Ussif, Desmond Owusu Agyeman and Gabriel Asante

    Citation: BMC Research Notes 2021 14:73

    Content type: Research note

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  19. Adolescence as one of the most challenging periods of humans’ growth is accompanied with major physical, behavioural, social-emotional, and neuroendocrine changes. Early maturation and eating disorders (EDs) h...

    Authors: Lida Daeie-Farshbaf, Mehrangiz Ebrahimi-Mameghani, Parvin Sarbakhsh, Neda Roshanravan and Ali Tarighat-Esfanjani

    Citation: BMC Research Notes 2021 14:72

    Content type: Research note

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  20. Early detection of specific signs and symptoms to predict severe illness is essential to prevent infant mortality. As a continuation of the results from the multicenter Young Infants Clinical Signs and Symptom...

    Authors: Shahira Shahid, Shiyam Sunder Tikmani, Kanwal Nayani, Ayesha Munir, Nick Brown, Anita K. M. Zaidi, Fyezah Jehan and Muhammad Imran Nisar

    Citation: BMC Research Notes 2021 14:71

    Content type: Research note

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  21. This study was planned to evaluate the genetic diversity in the admixed and Teli (a Hindu caste) populations of Maharashtra, India using 20 autosomal Short Tandem Repeat (STR) genetic markers. We further investig...

    Authors: Ashish Badiye, Neeti Kapoor, R. K. Kumawat, Shivani Dixit, Aditi Mishra, Akansha Dixit, Prachi Kathane, Sudeshna Bag, Vaishnavi Thakre, Kamlesh Kaitholia, Ankit Srivastava, Gyaneshwer Chaubey and Pankaj Shrivastava

    Citation: BMC Research Notes 2021 14:69

    Content type: Research note

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  22. Our objective was to apply next-generation sequence-based DNA barcoding to identify the remnant larval bloodmeals in wild-caught host-seeking (unengorged) Ixodes scapularis nymphs (n = 216). To infer host species...

    Authors: G. A. Lumsden, E. V. Zakharov, S. Dolynskyj, J. S. Weese, L. R. Lindsay and C. M. Jardine

    Citation: BMC Research Notes 2021 14:67

    Content type: Research note

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  23. The evaluation of physical activity for chronic hemodialysis patients is a new approach for patient global care. The objective of this work is to evaluate the physical activity in chronic hemodialysis patients...

    Authors: A. Bahadi, H. Lagtarna, S. Benbria, Y. Zajjari, D. Elkabbaj and N. Zemraoui

    Citation: BMC Research Notes 2021 14:65

    Content type: Research note

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  24. We developed an actuator-driven pulsed water jet device (ADPJ) for flexible neuroendoscopy to achieve effective tissue dissection with vasculature preservation. Although flexibility is a strong advantage for m...

    Authors: Tetsuya Kusunoki, Tomohiro Kawaguchi, Atsuhiro Nakagawa, Yuta Noguchi, Shin-Ichiro Osawa, Hidenori Endo, Toshiki Endo, Ryuta Saito, Masayuki Kanamori, Kuniyasu Niizuma and Teiji Tominaga

    Citation: BMC Research Notes 2021 14:64

    Content type: Research note

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  25. Data on gender representation in food and beverage advertisements may allow for a better understanding of how the food industry is targeting different audiences based on gender. Nonetheless, scant research on ...

    Authors: Lucila Rozas, Peter Busse, Joaquin Barnoya and Alejandra Garrón

    Citation: BMC Research Notes 2021 14:63

    Content type: Data note

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  26. The Glittre-ADL test (GA-T) is a functional capacity test that stands out for encompassing multiple tasks similar to activities of daily living. As ventilatory efficiency is one of the variables valued in the ...

    Authors: Hebert Olímpio Júnior, Agnaldo José Lopes, Fernando Silva Guimarães, Sergio Luiz Soares Marcos da Cunha Chermont and Sara Lúcia Silveira de Menezes

    Citation: BMC Research Notes 2021 14:62

    Content type: Research note

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  27. Rehabilitation of edentulous ridges to promote the insertion of dental implants has been the key indicator for retaining osseous structures since tooth extraction. Recombinant Bone Morphogenetic Protein-2(rhBM...

    Authors: Khushboo Jeevan Durge, Vidya Sudhindra Baliga, Shilpa Bangalore Sridhar, Prasad Vijayrao Dhadse and Gayatri Chandrakant Ragit

    Citation: BMC Research Notes 2021 14:61

    Content type: Research note

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  28. To assess parents’ perceptions about amblyopia and its causes, symptoms, risk factors, treatments, and the importance of follow-up and to evaluate their awareness regarding the consequences and critical compli...

    Authors: Ahmed Basheikh, Nizar Alhibshi, Motaz Bamakrid, Rasha Baqais, Mohammed Basendwah and Sara Howldar

    Citation: BMC Research Notes 2021 14:60

    Content type: Research note

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  29. Hepatitis B (HB) and C (HC) are two severe viral infectious diseases with a deleterious impact on global health. This study aimed to evaluate the prevalence of HB and HC in the Prospective Epidemiological Rese...

    Authors: Fariborz Mansour-Ghanaei, Farahnaz Joukar, Mohammadreza Naghipour, Soheil Hassanipour, Sara Yeganeh, Masood Sepehrimanesh and Mohammad Fathalipour

    Citation: BMC Research Notes 2021 14:59

    Content type: Research note

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  30. This study was designed to discover the dissemination of virulence genes in Methicillin-resistant Staphylococcus aureus from clinical, community and environmental settings.

    Authors: Deepshikha Bhowmik, Shiela Chetri, Bhaskar Jyoti Das, Debadatta Dhar Chanda and Amitabha Bhattacharjee

    Citation: BMC Research Notes 2021 14:58

    Content type: Research note

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  31. Human papillomavirus (HPV) gained momentum as a potential etiological factor for many types of cancers. Therefore, the aim of this study was to assess the prevalence of HPV-16 infection among Sudanese patients di...

    Authors: Fatima E. Mohamed, Leena N. Aldayem, Maisa A. Hemaida, Omayma Siddig, Zeinab H. Osman, Irene R. Shafig, Mohamed A. M. Salih, Mohamed S. Muneer, Rowa Hassan, Eiman Siddig Ahmed, Lamis Ahmed Hassan, Osama El Hadi Bakheet, Ali M. M. Edris, Ayman Ahmed, Nouh S. Mohamed and Emmanuel E. Siddig

    Citation: BMC Research Notes 2021 14:56

    Content type: Research note

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  32. Neonatal mortality is a global public health problem, and the efforts to reduce child mortality is one of the goals of the 2030 Agenda for Sustainable Development, launched in 2015 by the United Nations. The a...

    Authors: Lais Baroni, Rebecca Salles, Samella Salles, Marcel Pedroso, Jefferson Lima, Igor Morais, Lucas Carraro, Raphael de Freitas Saldanha, Carlos Sousa, Carlos Cardoso, Balthazar Paixño, Sérgio Cruz, Eduardo Ogasawara, Patrícia de Morais Mello Boccolini and Cristiano Siqueira Boccolini

    Citation: BMC Research Notes 2021 14:55

    Content type: Data note

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  33. Altitude integrates changes in environmental conditions that determine shifts in vegetation, including temperature, precipitation, solar radiation and edaphogenetic processes. In turn, vegetation alters soil b...

    Authors: Alexia Stokes, Guillermo Angeles, Fabien Anthelme, Eduardo Aranda-Delgado, Isabelle Barois, Manon Bounous, Nereyda Cruz-Maldonado, Thibaud Decaëns, Stéphane Fourtier, Grégoire T. Freschet, Quentin Gabriac, Daniel Hernández-Cáceres, Leonor Jiménez, Jing Ma, Zhun Mao, Beatriz Eugenia Marín-Castro…

    Citation: BMC Research Notes 2021 14:54

    Content type: Data note

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  34. Sequestosome 1 (p62/SQSTM1) is a multifunctional scaffold/adaptor protein encoded by the p62/SQSTM1 gene with function in cellular homeostasis. Mutations in the p62/SQSTM1 gene have been known to be associated wi...

    Authors: Emily P. Hurley and Brian E. Staveley

    Citation: BMC Research Notes 2021 14:53

    Content type: Research note

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  35. Differential alterations in gut microbiota and chronic low-grade inflammation play a critical role in the development of Type 2 diabetes (T2D). Here we aimed to investigate if dysbiosis of inflammation and ant...

    Authors: Prasanna Kulkarni, Poornima Devkumar and Indranil Chattopadhyay

    Citation: BMC Research Notes 2021 14:52

    Content type: Research note

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  36. Adults with Prader–Willi syndrome (PWS) require less energy intake to maintain body weight than the general adult population. This, combined with their altered gastrointestinal transit time, may impact microbi...

    Authors: Wendy J. Dahl, Jérémie Auger, Zainab Alyousif, Jennifer L. Miller and Thomas A. Tompkins

    Citation: BMC Research Notes 2021 14:51

    Content type: Research note

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  37. Toxoplasma gondii (T. gondii), an obligate intracellular apicomplexan parasite, could affect numerous warm-blooded animals, such as humans. Calcium-dependent protein kinases (CDPKs) are essential Ca2+ signaling m...

    Authors: Masoud Foroutan, Ali Dalir Ghaffari, Shahrzad Soltani, Hamidreza Majidiani, Ali Taghipour and Mohamad Sabaghan

    Citation: BMC Research Notes 2021 14:50

    Content type: Research note

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  38. Coronary artery disease (CAD) is an important cause of mortality and morbidity, therefore, recognizing its severity and related factors is important. This study was performed to evaluate the association betwee...

    Authors: Iman Mohseni, Afshin Shiri and Simindokht Mojahedin

    Citation: BMC Research Notes 2021 14:49

    Content type: Research note

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  39. Anxiety is reportedly prevalent in older adults with dementia living in care homes and, within this population, is most often assessed through caregiver reports. Heart rate variability (HRV) is a physiological...

    Authors: Milena A. Quinci and Arlene J. Astell

    Citation: BMC Research Notes 2021 14:48

    Content type: Research note

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  40. Trial registries were set up to improve transparency, remove duplication, improve awareness and avoid waste. Many trials never reach the point of patient enrolment due to a myriad of reasons. The aim of this s...

    Authors: Akke Vellinga, Kathryn Lambe, Paul O’Connor and Angela O’Dea

    Citation: BMC Research Notes 2021 14:47

    Content type: Research note

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  41. Toxoplasmosis, caused by Toxoplasma gondii, infects humans by consuming infected raw or undercooked meat and foods harboring mature oocysts. In this study, we assessed the prevalence of T. gondii in sheep and goa...

    Authors: Mojtaba Bahreh, Bahador Hajimohammadi and Gilda Eslami

    Citation: BMC Research Notes 2021 14:46

    Content type: Research note

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  42. Kazakhstan is a Central Asian crossroad of European and Asian populations situated along the way of the Great Silk Way. The territory of Kazakhstan has historically been inhabited by nomadic tribes and today i...

    Authors: Ulykbek Kairov, Askhat Molkenov, Saule Rakhimova, Ulan Kozhamkulov, Aigul Sharip, Daniyar Karabayev, Asset Daniyarov, Joseph H.Lee, Joseph D.Terwilliger, Ainur Akilzhanova and Zhaxybay Zhumadilov

    Citation: BMC Research Notes 2021 14:45

    Content type: Data note

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  43. In this 7-day pilot study we randomized healthy, normal-weight men and women to either a dietary intervention with methionine and cysteine restriction enriched in PUFA (Met/Cyslow + PUFA, n = 7) or with high cont...

    Authors: Thomas Olsen, Bente Øvrebø, Cheryl Turner, Nasser E. Bastani, Helga Refsum and Kathrine J. Vinknes

    Citation: BMC Research Notes 2021 14:43

    Content type: Research note

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  44. Currently the majority of non-culturable microbes in sea water are yet to be discovered, Nanopore offers a solution to overcome the challenging tasks to identify the genomes and complex composition of oceanic ...

    Authors: M. Liem, T. Regensburg-Tuïnk, C. Henkel, H. Jansen and H. Spaink

    Citation: BMC Research Notes 2021 14:42

    Content type: Research note

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  45. Contaminated poultry feeds can be a major source of E. coli and Salmonella infections in poultry. This study aimed at determining microbial load, prevalence and antimicrobial resistance profiles of Salmonella sp....

    Authors: Dorica Gakii Ngai, Anthony Kebira Nyamache and Omwoyo Ombori

    Citation: BMC Research Notes 2021 14:41

    Content type: Research note

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