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  1. Traumatic perforation of the tympanic membrane may be due to direct or indirect source. The aim of the study is to profile the various aetiologies of traumatic tympanic membrane perforation in Ilorin, north ce...

    Authors: Olushola A Afolabi, Shuaib K Aremu, Biodun S Alabi and S Segun-Busari

    Citation: BMC Research Notes 2009 2:232

    Content type: Short Report

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  2. The zebrafish, Danio rerio, possesses the paralogous genes aplnra and aplnrb that are duplicates of an ancestral orthologue of the human APLNR gene encoding a G-protein coupled receptor that binds the peptide lig...

    Authors: Svanhild Nornes, Ben Tucker and Michael Lardelli

    Citation: BMC Research Notes 2009 2:231

    Content type: Short Report

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  3. We used Global Positioning System (GPS) data from radiocollared pumas (Puma concolor) to identify kill sites of pumas preying upon an endangered population of bighorn sheep (Ovis canadensis) in southern Californi...

    Authors: Sean M Clemenza, Esther S Rubin, Christine K Johnson, Randall A Botta and Walter M Boyce

    Citation: BMC Research Notes 2009 2:230

    Content type: Short Report

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  4. The fibroblast-populated 3D collagen matrix is a model of tissue and healing which has been used since the 1980's. It was hypothesized that anchorage disruption of the collagen matrix would produce p53-depende...

    Authors: Mark A Carlson, Amy K Prall, Jeremiah J Gums, Alex Lesiak and Valerie K Shostrom

    Citation: BMC Research Notes 2009 2:229

    Content type: Short Report

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  5. Several pathogens that cause important zoonotic diseases have been frequently associated with armadillos and other xenarthrans. This mammal group typically has evolved on the South American continent and many ...

    Authors: Virgínia B Richini-Pereira, Sandra MG Bosco, Raquel C Theodoro, Lígia Barrozo, Silvia CB Pedrini, Patrícia S Rosa and Eduardo Bagagli

    Citation: BMC Research Notes 2009 2:228

    Content type: Short Report

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  6. The shikimate pathway is an attractive target for the development of antitubercular agents because it is essential in Mycobacterium tuberculosis, the causative agent of tuberculosis, but absent in humans. M. tube...

    Authors: Valnês S Rodrigues Junior, Ardala Breda, Diógenes S Santos and Luiz A Basso

    Citation: BMC Research Notes 2009 2:227

    Content type: Short Report

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  7. The plasticizer di-(2-ethylhexyl) phthalate (DEHP) has been shown to stimulate a non-allergy related immune response with increased levels of IgG1 and IgG2a, but not IgE, after co-administration with the model...

    Authors: Søren T Larsen and Gunnar D Nielsen

    Citation: BMC Research Notes 2009 2:225

    Content type: Short Report

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  8. Francisella tularensis is the etiologic agent of tularemia and is classified as a select agent by the Centers for Disease Control and Prevention. Currently four known subspecies of F. tularensis that differ in vi...

    Authors: Dawn N Birdsell, Tasha Stewart, Amy J Vogler, Elisabeth Lawaczeck, Alisa Diggs, Tammy L Sylvester, Jordan L Buchhagen, Raymond K Auerbach, Paul Keim and David M Wagner

    Citation: BMC Research Notes 2009 2:223

    Content type: Short Report

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  9. Attributes of teams could affect the quality of care delivered in primary care. The aim of this study was to systematically review studies conducted within the UK NHS primary care that have measured team clima...

    Authors: Teik T Goh and Martin P Eccles

    Citation: BMC Research Notes 2009 2:222

    Content type: Short Report

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  10. Research has shown that fecal biomarkers are useful to assess the activity of inflammatory bowel disease (IBD). The aim of the study is: to evaluate the efficacy of the fecal lactoferrin and calprotectin as in...

    Authors: Andrea Vieira, Chia Bin Fang, Ernani Geraldo Rolim, Wilmar Artur Klug, Flávio Steinwurz, Lucio Giovanni Battista Rossini and Paulo Azevedo Candelária

    Citation: BMC Research Notes 2009 2:221

    Content type: Short Report

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  11. High-throughput screening of protein-protein interactions opens new systems biology perspectives for the comprehensive understanding of cell physiology in normal and pathological conditions. In this context, y...

    Authors: Johann Pellet, Laurène Meyniel, Pierre-Olivier Vidalain, Benoît de Chassey, Lionel Tafforeau, Vincent Lotteau, Chantal Rabourdin-Combe and Vincent Navratil

    Citation: BMC Research Notes 2009 2:220

    Content type: Technical Note

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  12. C21, the C-terminal peptide of thrombospondin-4, has growth promoting activity and was discovered as one of several erythropoietin-dependent endothelial proteins. C21 stimulates red cell formation in anemic mi...

    Authors: Gulzhakhan Sadvakassova, Monica C Dobocan and Luis F Congote

    Citation: BMC Research Notes 2009 2:215

    Content type: Short Report

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  13. Single nucleotide polymorphism (SNP) genotyping is a major activity in biomedical research. Scientists prefer to have a facile access to the results which may require conversions between data formats. First ha...

    Authors: Bowang Chen, Stefan Wilkening, Marion Drechsel and Kari Hemminki

    Citation: BMC Research Notes 2009 2:214

    Content type: Technical Note

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  14. Toxoplasmosis in immuno-compromised hosts manifests primarily as a life threatening condition, toxoplasmic encephalitis. However, there is scarce information about the magnitude of Toxoplasma gondii infection amo...

    Authors: Techalew Shimelis, Mekashaw Tebeje, Endale Tadesse, Belete Tegbaru and Ashenafi Terefe

    Citation: BMC Research Notes 2009 2:213

    Content type: Short Report

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  15. We are correcting the abstract of our published article ([1]). The sentence that starts "We observe that 4.5% of MPSS tags...." was not scientifically complete in the original abstract, having only two of the fou...

    Authors: Rajkumar Sasidharan, Ashish Agarwal, Joel Rozowsky and Mark Gerstein

    Citation: BMC Research Notes 2009 2:211

    Content type: Erratum

    Published on:

    The original article was published in BMC Research Notes 2009 2:150

  16. To analyze gene function in mammalian cells tetracycline inducible expression of a gene-of-interest at a specific genomic location (Flp-In T-REx™) is most attractive. However, leakiness of basal transgene expr...

    Authors: Sabine Senkel, Christoph Waldner, Gerhart U Ryffel and Heike Thomas

    Citation: BMC Research Notes 2009 2:210

    Content type: Technical Note

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  17. Bovine herpesviruses type 1 (BoHV1) and type 5 (BoHV5) are two closely related pathogens of cattle. The identity of the two viruses on the amino acid level averages 82%. Despite their high antigenetic similari...

    Authors: Evgeni Gabev, Cornel Fraefel, Mathias Ackermann and Kurt Tobler

    Citation: BMC Research Notes 2009 2:209

    Content type: Short Report

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  18. There is little confidence in the consistency of estimation of DNA concentrations when samples move between laboratories. Evidence on this consistency is largely anecdotal. Therefore there is a need first to m...

    Authors: Jay Brown, Alexander N Donev, Charalampos Aslanidis, Pippa Bracegirdle, Katherine P Dixon, Manuela Foedinger, Rhian Gwilliam, Matthew Hardy, Thomas Illig, Xiayi Ke, Dagni Krinka, Camilla Lagerberg, Päivi Laiho, David H Lewis, Wendy McArdle, Simon Patton…

    Citation: BMC Research Notes 2009 2:208

    Content type: Short Report

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  19. Deschampsia antarctica shows tolerance to extreme environmental factors such as low temperature, high light intensity and an increasing UV radiation as result of the Antarctic ozone layer thinning. It is very lik...

    Authors: Jaime R Sánchez-Venegas, Alejandro Navarrete, Jorge Dinamarca, León A Bravo Ramírez, Ana Gutiérrez Moraga and Manuel Gidekel

    Citation: BMC Research Notes 2009 2:207

    Content type: Short Report

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  20. Our SigWin-detector discovers significantly enriched windows of (genomic) elements in any sequence of values (genes or other genomic elements in a DNA sequence) in a fast and reproducible way. However, since i...

    Authors: Wim C de Leeuw, Han Rauwerda, Márcia A Inda, Oskar Bruning and Timo M Breit

    Citation: BMC Research Notes 2009 2:205

    Content type: Technical Note

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  21. The reindeer lichen is the product of a mutualistic relationship between a fungus and an algae. Lichen demonstrate a remarkable capacity to tolerate dehydration. This tolerance is driven by a variety of bioche...

    Authors: Sini Junttila, Kean-Jin Lim and Stephen Rudd

    Citation: BMC Research Notes 2009 2:204

    Content type: Short Report

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  22. BMI was increased (>25) in 22% of young healthy subjects. Increased cholesterol values (>5.0 mmol/L) were found in 23% of subjects, LDL-C (>3.0 mmol/L) in 23%, triglycerides (>1.7 mmol/L) in 11% of subjects. W...

    Authors: Jadranka Sertic, Ljiljana Juricic, Hana Ljubic, Tamara Bozina, Jasna Lovric, Jasenka Markeljevic, Bojan Jelakovic, Marijan Merkler and Zeljko Reiner

    Citation: BMC Research Notes 2009 2:203

    Content type: Short Report

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  23. The availability of research platforms like the web tools of the National Center for Biotechnology Information (NCBI) has transformed the time-consuming task of identifying candidate genes from genetic studies...

    Authors: Rajani S Sadasivam, Gayathri Sundar, Laura K Vaughan, Murat M Tanik and Donna K Arnett

    Citation: BMC Research Notes 2009 2:201

    Content type: Short Report

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  24. In cancer care, a GP's work is rarely defined clearly. Our aim was to assess GPs' work with cancer patients in France and in Norway, where the roles of the GP and the organization of the system are rather diff...

    Authors: Lise Demagny, Knut Holtedahl, Janine Bachimont, Tommy Thorsen, Alain Letourmy and Martine Bungener

    Citation: BMC Research Notes 2009 2:200

    Content type: Short Report

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  25. Consolidating transcriptome data of non-human primates is essential to annotate primate genome sequences, and will facilitate research using non-human primates in the genomic era. Macaca fascicularis is a macaque...

    Authors: Naoki Osada, Makoto Hirata, Reiko Tanuma, Yutaka Suzuki, Sumio Sugano, Keiji Terao, Jun Kusuda, Yosuke Kameoka, Katsuyuki Hashimoto and Ichiro Takahashi

    Citation: BMC Research Notes 2009 2:199

    Content type: Data Note

    Published on:

  26. The Copper/Zinc superoxide dismutase (Cu/ZnSOD) gene, SOD gene, was isolated from a Deschampsia antarctica Desv. by cDNA library screening. The expression of SOD gene in the leaves of D. antarctica was determined...

    Authors: Jaime R Sánchez-Venegas, Jorge Dinamarca, Ana Gutiérrez Moraga and Manuel Gidekel

    Citation: BMC Research Notes 2009 2:198

    Content type: Short Report

    Published on:

  27. Our aim was to develop an objective computerised system for measuring different types of retinal haemorrhages in differing digital images, for use as a research tool. Despite developing various fully automated...

    Authors: Tariq Aslam, Paul Chua, Matthew Richardson, Praveen Patel and Mohammed Musadiq

    Citation: BMC Research Notes 2009 2:196

    Content type: Technical Note

    Published on:

  28. The functional integration of the neuro-, endocrine- and immune-systems suggests that the transcriptome of white blood cells may reflect neuropsychiatric states, and be used as a non-invasive diagnostic indica...

    Authors: Johan H van Heerden, Ana Conesa, Dan J Stein, David Montaner, Vivienne Russell and Nicola Illing

    Citation: BMC Research Notes 2009 2:195

    Content type: Short Report

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  29. Succinate dehydrogenase (SDH) and fumarate hydratase (FH) are tricarboxylic acid (TCA) cycle enzymes that are also known to act as tumour suppressor genes. Increased succinate or fumarate levels as a consequen...

    Authors: Katie T Huang, Alexander Dobrovic and Stephen B Fox

    Citation: BMC Research Notes 2009 2:194

    Content type: Short Report

    Published on:

  30. Mitochondria (mt) contain their own autonomously replicating DNA, constituted as a small circular genome encoding essential subunits of the respiratory chain. Mt DNA is characterized by a genetic code which di...

    Authors: Joachim EM Jacob, Bartel Vanholme, Thomas Van Leeuwen and Godelieve Gheysen

    Citation: BMC Research Notes 2009 2:192

    Content type: Short Report

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  31. Bub1 is a component of the spindle assembly checkpoint, a surveillance mechanism that maintains chromosome stability during M-phase. Bub1 is essential during the early stages of embryogenesis, with homozygous BUB...

    Authors: Valerie Tilston, Stephen S Taylor and David Perera

    Citation: BMC Research Notes 2009 2:190

    Content type: Short Report

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  32. Saffron (Crocus sativus) is considered the world's most expensive spice. Used mainly as a colorant for foodstuffs, it is highly appreciated for its aromatic and flavouring properties. Since no molecular markers f...

    Authors: Angela Rubio-Moraga, Raquel Castillo-López, Lourdes Gómez-Gómez and Oussama Ahrazem

    Citation: BMC Research Notes 2009 2:189

    Content type: Short Report

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  33. The cultivated strawberry Fragaria ×ananassa is one of the most economically-important soft-fruit species. Few structural genomic resources have been reported for Fragaria and there exists an urgent need for the ...

    Authors: Julio Bonet, Elena Lopez Girona, Daniel J Sargent, Monica C Muñoz-Torres, Amparo Monfort, Albert G Abbott, Pere Arús, David W Simpson and Jahn Davik

    Citation: BMC Research Notes 2009 2:188

    Content type: Short Report

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  34. The rK39 strip test is reported to be simple, sensitive, specific, non-invasive and economical test. Since this method is supposed to be patient friendly, it may easily be accepted for sero-epidemiological sur...

    Authors: Dharmendra P Singh, Shyam Sundar and Tribhuban M Mohapatra

    Citation: BMC Research Notes 2009 2:187

    Content type: Short Report

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  35. Post caesarean wound infection is not only a leading cause of prolonged hospital stay but a major cause of the widespread aversion to caesarean delivery in developing countries. In order to control and prevent...

    Authors: Oliver C Ezechi, Asuquo Edet, Hakim Akinlade, Chidinma V Gab-Okafor and Ebiere Herbertson

    Citation: BMC Research Notes 2009 2:186

    Content type: Short Report

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  36. Though the biological process of aphid feeding is well documented, no one to date has sought to apply it as a tool to screen the biological responses to chemicals and drugs, in ecotoxicology, genotoxicology an...

    Authors: Aviv Dombrovsky, Terence Neil Ledger, Gilbert Engler and Alain Robichon

    Citation: BMC Research Notes 2009 2:185

    Content type: Technical Note

    Published on:

  37. In eusocial hymenopteran insects, foraging genes, members of the cGMP-dependent protein kinase family, are considered to contribute to division of labor through behavioral caste differentiation. However, the rela...

    Authors: Yosuke Kodaira, Hajime Ohtsuki, Jun Yokoyama and Masakado Kawata

    Citation: BMC Research Notes 2009 2:184

    Content type: Short Report

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