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  1. Our previous study on ripe apples from a progeny of a cross between the apple cultivars ‘Prima’ and ‘Fiesta’ showed a hotspot of mQTLs for phenolic compounds at the top of LG16, both in peel and in flesh tissu...

    Authors: Sabaz Ali Khan, Jan G Schaart, Jules Beekwilder, Andrew C Allan, Yury M Tikunov, Evert Jacobsen and Henk J Schouten
    Citation: BMC Research Notes 2012 5:618
  2. The tissue-specific Unigene Sets derived from more than one million expressed sequence tags (ESTs) in the NCBI, GenBank database offers a platform for identifying significantly and differentially expressed tis...

    Authors: Mousami Srivastava, Pankaj Khurana and Ragumani Sugadev
    Citation: BMC Research Notes 2012 5:617
  3. Toll-like receptors (TLRs) are evolutionarily conserved pattern recognition receptors that mediate host responses to pathogens. To date, at least 10 different TLRs have been identified in chickens including TL...

    Authors: Michael St Paul, Neda Barjesteh, Sarah Paolucci, Yanlong Pei and Shayan Sharif
    Citation: BMC Research Notes 2012 5:616
  4. Evaluating the impact of genomic variations (GV) on protein-coding transcripts is an important step in identifying variants of functional significance. Currently available programs for variant annotation depen...

    Authors: Ismael A Vergara, Christian Frech and Nansheng Chen
    Citation: BMC Research Notes 2012 5:615
  5. Body-focused repetitive behaviors (BFRBs) that include skin picking (dermatillomania), hair pulling (trichotillomania) and nail biting (onychophagia), lead to harmful physical and psychological sequelae.

    Authors: Efaza Umar Siddiqui, Syed Saad Naeem, Haider Naqvi and Bilal Ahmed
    Citation: BMC Research Notes 2012 5:614
  6. The acceptability of female-controlled biomedical prevention technologies has not been established in Papua New Guinea, the only country in the Pacific region experiencing a generalised, moderate-prevalence HI...

    Authors: Andrew Vallely, Lisa Fitzgerald, Voletta Fiya, Herick Aeno, Angela Kelly, Joyce Sauk, Martha Kupul, James Neo, John Millan, Peter Siba and John M Kaldor
    Citation: BMC Research Notes 2012 5:613
  7. Human plasma, representing the most complete record of the individual phenotype, is an appealing sample for proteomics analysis in clinical applications. Up to today, the major obstacle in a proteomics study o...

    Authors: Claudia Boccardi, Silvia Rocchiccioli, Antonella Cecchettini, Alberto Mercatanti and Lorenzo Citti
    Citation: BMC Research Notes 2012 5:612
  8. In Germany, case management in a palliative care unit was first implemented in 2005 at the Department of Palliative Medicine at the University Hospital Cologne. One of the purposes of this case management is t...

    Authors: Ulrike Kuhn, Anne Düsterdiek, Maren Galushko, Christina Dose, Thomas Montag, Christoph Ostgathe and Raymond Voltz
    Citation: BMC Research Notes 2012 5:611
  9. Image registration is one of the most important and universally useful computational tasks in biomedical image analysis. A recent article by Xing & Qiu (IEEE Transactions on Pattern Analysis and Machine Intell...

    Authors: Torsten Rohlfing and Brian Avants
    Citation: BMC Research Notes 2012 5:610
  10. Clostridium difficile ribotype 027 has become increasingly prevalent in European countries. The clinical picture varies from self-limiting diarrhea to pseudomembranous colitis with toxic megacolon and ultimately ...

    Authors: Kirstine Kobberøe Søgaard, Tove Ejlertsen and Henrik Carl Schønheyder
    Citation: BMC Research Notes 2012 5:609
  11. Heterotrimeric G-proteins, consisting of three subunits Gα, Gβ and Gγ are present in most eukaryotes and mediate signaling in numerous biological processes. In plants, Gγ subunits were shown to provide functio...

    Authors: Yuri Trusov, David Chakravorty and José Ramón Botella
    Citation: BMC Research Notes 2012 5:608
  12. Bladder cancer is the seventh most common cancer worldwide and over 90% are transitional cell carcinoma (TCC). At the first time of diagnosis at least 70% of TCC present as superficial bladder cancer. Because ...

    Authors: Donatella Conconi, Elena Panzeri, Serena Redaelli, Giorgio Bovo, Marco Volante, Paolo Viganò, Guido Strada, Leda Dalprà and Angela Bentivegna
    Citation: BMC Research Notes 2012 5:607
  13. Investigators conduct survey studies for a variety of reasons. Poor participant response rates are common, however, and may limit the generalizability and utility of results. The objective of this study was to...

    Authors: Melissa J Parker, Asmaa Manan and Sara Urbanski
    Citation: BMC Research Notes 2012 5:605
  14. In the big data era, biomedical research continues to generate a large amount of data, and the generated information is often stored in a database and made publicly available. Although combining data from mult...

    Authors: Mizuki Morita, Yoshinobu Igarashi, Maori Ito, Yi-An Chen, Chioko Nagao, Yuki Sakaguchi, Ryuichi Sakate, Tohru Masui and Kenji Mizuguchi
    Citation: BMC Research Notes 2012 5:604
  15. Clarithromycin (CLR) is the most commonly recommended antibiotic in Helicobacter pylori eradication regimens, but the prevalence of CLR-resistant H. pylori is increasing. CLR resistance is associated with mutatio...

    Authors: Türkan Sakinc, Barbara Baars, Nicole Wüppenhorst, Manfred Kist, Johannes Huebner and Wolfgang Opferkuch
    Citation: BMC Research Notes 2012 5:603
  16. Primary hyperaldosteronism (PA) is a serious and potentially debilitating disease. Detailed guidelines have been written to guide endocrinologists in establishing the diagnosis of PA as well as in subtype clas...

    Authors: Brian T Layden, Allison J Hahr and Dina M Elaraj
    Citation: BMC Research Notes 2012 5:602
  17. Bovine neonatal pancytopenia (BNP) is a syndrome characterised by thrombocytopenia associated with marked bone marrow destruction in calves, widely reported since 2007 in several European countries and since 2...

    Authors: Eleanor Laming, Eleonora Melzi, Sandra FE Scholes, Maira Connelly, Charlotte R Bell, Keith T Ballingall, Mark P Dagleish, Mara S Rocchi and Kim Willoughby
    Citation: BMC Research Notes 2012 5:599
  18. The high blood lipid levels and obesity are one of the main risk factors for cardiovascular diseases, and the atherosclerotic process begins in childhood. Some environmental factors are supposed to be involved...

    Authors: Ana Elisa Madalena Rinaldi, Erick Prado de Oliveira, Fernando Moreto, Gleice Fernanda Costa Pinto Gabriel, José Eduardo Corrente and Roberto Carlos Burini
    Citation: BMC Research Notes 2012 5:598
  19. Although the risk of hepatitis B virus (HBV) was reported to be higher in military personnel than the general population in Saudi Arabia (SA), there is lack of studies assessing HBV awareness among them. The o...

    Authors: Majid S Al-Thaqafy, Hanan H Balkhy, Ziad Memish, Yahya M Makhdom, Adel Ibrahim, Abdulfattah Al-Amri and Abdulhakeem Al-Thaqafi
    Citation: BMC Research Notes 2012 5:597
  20. Metabolomics is an emerging high-throughput approach to systems biology, but data analysis tools are lacking compared to other systems level disciplines such as transcriptomics and proteomics. Metabolomic data...

    Authors: Ben Ernest, Jessica R Gooding, Shawn R Campagna, Arnold M Saxton and Brynn H Voy
    Citation: BMC Research Notes 2012 5:596
  21. Cutaneous squamous cell carcinoma (SCC) of the hands and fingers are sometimes locally aggressive; with higher rates of regional metastasis than other cutaneous SCC, although distant metastasis is rare.

    Authors: Kenzo Uchida, Tsuyoshi Miyazaki, Hideaki Nakajima, Kohei Negoro, Daisuke Sugita, Shuji Watanabe, Mitsuo Yoshimura, Hiroshi Itoh and Hisatoshi Baba
    Citation: BMC Research Notes 2012 5:595
  22. The implementation of capitated payment has driven medical institutions through developing balance billing for medical services. By exploring the patients’ decision-making factors on different self-pay items, ...

    Authors: Ching-Kuo Wei, Shun-Mu Wang and Jen-Chieh Lin
    Citation: BMC Research Notes 2012 5:592
  23. Use of energy drinks has significantly increased in recent times. Besides athletes, teenagers and students are among the most common consumers. However, popularity is also increasing among the younger and olde...

    Authors: Asma Usman and Ambreen Jawaid
    Citation: BMC Research Notes 2012 5:591
  24. Cervical squamous intra-epithelial lesions (SIL) are more frequent in HIV-positive women overall. However the appropriate age at which to begin and end cervical cancer screening for early detection of lesions ...

    Authors: Julius Atashili, William C Miller, Jennifer S Smith, Peter M Ndumbe, George M Ikomey, Joseph Eron, Allen C Rinas, Evan Myers and Adaora A Adimora
    Citation: BMC Research Notes 2012 5:590
  25. The Indonesia Maternal Mortality Rate (MMR) of 420/100.00 live births remains among the highest in East Asia while coverage of births assisted by skilled providers is still low. Traditional beliefs have been a...

    Authors: Yenita Agus, Shigeko Horiuchi and Sarah E Porter
    Citation: BMC Research Notes 2012 5:589
  26. Although allied health is considered to be one 'unit' of healthcare providers, it comprises a range of disciplines which have different training and ways of thinking, and different tasks and methods of patient...

    Authors: Lucylynn M Lizarondo, Karen Grimmer-Somers, Saravana Kumar and Alan Crockett
    Citation: BMC Research Notes 2012 5:588
  27. Analyses of coprolites have contributed to the knowledge of diet as well as infectious diseases in ancient populations. Results of paleoparasitological studies showed that prehistoric groups were exposed to sp...

    Authors: Luciana Sianto, Isabel Teixeira-Santos, Marcia Chame, Sergio M Chaves, Sheila M Souza, Luiz Fernando Ferreira, Karl Reinhard and Adauto Araujo
    Citation: BMC Research Notes 2012 5:586
  28. Inguinal hernia repair remains the commonest operation performed by general surgeons all over the world. There is paucity of published data on surgical management of inguinal hernias in our environment. This s...

    Authors: Joseph B Mabula and Phillipo L Chalya
    Citation: BMC Research Notes 2012 5:585
  29. Ventricular septal rupture (VSR), a mechanical complication following an acute myocardial infarction (MI), is thought to result from coagulation necrosis due to lack of collateral reperfusion. Although the gol...

    Authors: Surinder Dhaliwal, Robin Ducas, Liu Shuangbo, David Horne, John Lee, Farrukh Hussain, Iain DC Kirkpatrick and Davinder S Jassal
    Citation: BMC Research Notes 2012 5:583
  30. Accurate interpretation of HIV drug resistance (HIVDR) testing is challenging, yet important for patient care. We compared genotyping interpretation, based on the Stanford University HIV Drug Resistance Databa...

    Authors: Awachana Jiamsakul, Rami Kantor, Patrick CK Li, Sunee Sirivichayakul, Thira Sirisanthana, Pacharee Kantipong, Christopher KC Lee, Adeeba Kamarulzaman, Winai Ratanasuwan, Rossana Ditangco, Thida Singtoroj and Somnuek Sungkanuparph
    Citation: BMC Research Notes 2012 5:582
  31. Certain bacteria from the genus Streptomyces are currently used as biological control agents against plant pathogenic fungi. Hydrolytic enzymes that degrade fungal cell wall components, such as chitinases, are su...

    Authors: Wimal Ubhayasekera and Magnus Karlsson
    Citation: BMC Research Notes 2012 5:581
  32. Functional annotation of every gene in the mouse genome is a herculean task that requires a multifaceted approach. Many large-scale initiatives are contributing to this undertaking. The International Knockout ...

    Authors: Teresa M Gunn
    Citation: BMC Research Notes 2012 5:580
  33. According to the National Health survey only 3% of the population has controlled hypertension. This study was designed to elucidate the knowledge about hypertension in hypertensive patients at three tertiary c...

    Authors: Aysha Almas, Saniya Siraj Godil, Saima Lalani, Zahra Aziz Samani and Aamir Hameed Khan
    Citation: BMC Research Notes 2012 5:579
  34. To describe the long term outcome of patients who interrupted highly active antiretroviral therapy (HAART) once, identify the variables associated with earlier need to re-start HAART, and the response when the...

    Authors: Carmen Machado, María José Ríos-Villegas, Juan Gálvez-Acebal, Angel Domínguez-Castellano, Felipe Fernández-Cuenca, Virginia Palomo, Miguel Angel Muniain and Jesús Rodríguez-Baño
    Citation: BMC Research Notes 2012 5:578
  35. We present a compendium of N-ethyl-N-nitrosourea (ENU)-induced mouse mutations, identified in our laboratory over a period of 10 years either on the basis of phenotype or whole genome and/or whole exome sequencin...

    Authors: Carrie N Arnold, Michael J Barnes, Michael Berger, Amanda L Blasius, Katharina Brandl, Ben Croker, Karine Crozat, Xin Du, Celine Eidenschenk, Philippe Georgel, Kasper Hoebe, Hua Huang, Zhengfan Jiang, Philippe Krebs, Diantha La Vine, Xiaohong Li…
    Citation: BMC Research Notes 2012 5:577
  36. In developing countries, mothers usually manage diarrhea at home with the pattern of management depending on perceived disease severity and beliefs. The study was carried out with the objective of determining ...

    Authors: Mukhtar Ansari, Mohamed Izham Mohamed Ibrahim, Mohamed Azmi Hassali, P Ravi Shankar, Arun Koirala and Noor Jang Thapa
    Citation: BMC Research Notes 2012 5:576
  37. Transcription of the cathelicidin antimicrobial peptide (CAMP) gene is induced by binding of the bioactive form of vitamin D, 1,25-dihydroxyvitamin D, to the vitamin D receptor. Significant levels of the protein ...

    Authors: Brian M Dixon, Tyler Barker, Toni McKinnon, John Cuomo, Balz Frei, Niels Borregaard and Adrian F Gombart
    Citation: BMC Research Notes 2012 5:575
  38. Recently, various evolution-related journals adopted policies to encourage or require archiving of phylogenetic trees and associated data. Such attention to practices that promote sharing of data reflects rapi...

    Authors: Arlin Stoltzfus, Brian O'Meara, Jamie Whitacre, Ross Mounce, Emily L Gillespie, Sudhir Kumar, Dan F Rosauer and Rutger A Vos
    Citation: BMC Research Notes 2012 5:574
  39. Poor response rates in prevalence surveys can lead to nonresponse bias thereby compromising the validity of prevalence estimates. We conducted a telephone survey of randomly selected households to estimate the...

    Authors: Megan Knoll, Lianne Soller, Moshe Ben-Shoshan, Daniel Harrington, Joey Fragapane, Lawrence Joseph, Sebastien La Vieille, Yvan St-Pierre, Kathi Wilson, Susan Elliott and Ann Clarke
    Citation: BMC Research Notes 2012 5:572
  40. Meta-analysis is a statistical method for combining the results of primary studies. It is often used in systematic reviews and is increasingly a method and topic that appears in student dissertations. MetaLigh...

    Authors: James Thomas, Sergio Graziosi, Steve Higgins, Robert Coe, Carole Torgerson and Mark Newman
    Citation: BMC Research Notes 2012 5:571

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