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  1. The coordinated activity of different flavonoid biosynthesis genes in Arabidopsis thaliana results in tissue-specific accumulation of flavonols, anthocyanins and proanthocyanidins (PAs). These compounds possess d...

    Authors: Christiane Katja Kleindt, Ralf Stracke, Frank Mehrtens and Bernd Weisshaar
    Citation: BMC Research Notes 2010 3:255
    Content type: Short Report Published on:

  2. There is little published on current Saudi diabetic patients' practices when they are exposed to foot disorders such as open wound, ulcer, and skin cracks. These factors are usually influenced by local culture...

    Authors: Balkees A Bakhotmah and Hasan A Alzahrani
    Citation: BMC Research Notes 2010 3:254
    Content type: Short Report Published on:

  3. Transgenic labels that allow the visualization of specific populations of neurons have proven to be powerful tools for research. Further developing such resources to label additional cell types and specific or...

    Authors: Robert W Burgess and Peter G Fuerst
    Citation: BMC Research Notes 2010 3:253
    Content type: Short Report Published on:

  4. The CHD7 (Chromodomain Helicase DNA binding protein 7) gene encodes a member of the chromodomain family of ATP-dependent chromatin remodeling enzymes. Mutations in the CHD7 gene are found in individuals with CHAR...

    Authors: Christian Colin, Flávia S Tobaruella, Ricardo G Correa, Mari C Sogayar and Marcos A Demasi
    Citation: BMC Research Notes 2010 3:252
    Content type: Short Report Published on:

  5. Mycobacterium avium subsp. paratuberculosis (MAP) is the etiological agent of paratuberculosis (Johne's disease) in ruminants and is suggested to be one of the etiologic factors in Crohn's disease in humans. Cont...

    Authors: Monika Dzieciol, Patrick Volgger, Johannes Khol, Walter Baumgartner, Martin Wagner and Ingeborg Hein
    Citation: BMC Research Notes 2010 3:251
    Content type: Short Report Published on:

  6. The application of mobile computing and communication technology is rapidly expanding in the fields of health care and public health. This systematic review will summarise the evidence for the effectiveness of...

    Authors: Caroline Free, Gemma Phillips, Lambert Felix, Leandro Galli, Vikram Patel and Philip Edwards
    Citation: BMC Research Notes 2010 3:250
    Content type: Project Note Published on:

  7. The synergy between tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection on perceived stigma is not well studied. The objective of this study was to assess the effect of TB/HIV co-infection on...

    Authors: Amare Deribew, Yohannes HaileMichael, Markos Tesfaye, Dejene Desalegn, Ajeme Wogi and Shallo Daba
    Citation: BMC Research Notes 2010 3:249
    Content type: Short Report Published on:

  8. Aedes aegypti is the principal vector of dengue and yellow fever viruses. The availability of the sequenced and annotated genome enables genome-wide analyses of gene expression in this mosquito. The large amount ...

    Authors: Sumudu N Dissanayake, Jose MC Ribeiro, Mei-Hui Wang, William A Dunn, Guiyun Yan, Anthony A James and Osvaldo Marinotti
    Citation: BMC Research Notes 2010 3:248
    Content type: Data Note Published on:

  9. Concurrent chemoradiotherapy (CCRT) after breast surgery was investigated by few authors and remains controversial, because of concerns of toxicity with taxanes/anthracyclines and radiation. This treatment is ...

    Authors: Nabil Ismaili, Sanaa Elmajjaoui, Issam Lalya, Lamia Boulaamane, Rhizlane Belbaraka, Halima Abahssain, Rachi Aassab, Noureddine Benjaafar, Brahim El Khalil El Guddari, Omar El Mesbahi, Yassir Sbitti, Mohammed Ismaili and Hassan Errihani
    Citation: BMC Research Notes 2010 3:247
    Content type: Short Report Published on:

  10. Primary care may be a key setting for suicide prevention. However, comparatively little is known about the services available in primary care for suicide prevention. The aims of the current study were to descr...

    Authors: Pooja Saini, Kirsten Windfuhr, Anna Pearson, Damian Da Cruz, Caroline Miles, Lis Cordingley, David While, Nicola Swinson, Alyson Williams, Jenny Shaw, Louis Appleby and Navneet Kapur
    Citation: BMC Research Notes 2010 3:246
    Content type: Short Report Published on:

  11. Meiotic recombination in eukaryotes requires two homologues of the E. coli RecA proteins: Rad51 and Dmc1. Both proteins play important roles in the binding of single stranded DNA, homology search, strand invasion...

    Authors: Upendra Kumar Devisetty, Katie Mayes and Sean Mayes
    Citation: BMC Research Notes 2010 3:245
    Content type: Short Report Published on:

  12. Brucellosis is a worldwide anthropozoonotic disease caused by an in vivo intracellular pathogen belonging to genus Brucella. The characterization of brucelae transcriptome's during host-pathogen interaction has b...

    Authors: Carlos A Rossetti, Cristi L Galindo, Harold R Garner and L Garry Adams
    Citation: BMC Research Notes 2010 3:244
    Content type: Short Report Published on:

  13. Alcohol is a commonly used social drug and driving under influence is a well-established risk factor for traffic accidents[1]. To improve road safety, legal limits are set for blood alcohol concentration (BAC) an...

    Authors: Judith Hegeman, Vivian Weerdesteyn, Bart JF van den Bemt, Bart Nienhuis, Jacques van Limbeek and Jacques Duysens
    Citation: BMC Research Notes 2010 3:243
    Content type: Short Report Published on:

  14. Collybistin (CB), a neuron-specific guanine nucleotide exchange factor, has been implicated in targeting gephyrin-GABAA receptors clusters to inhibitory postsynaptic sites. However, little is known about addition...

    Authors: Andrea L Sertie, Gustavo de Alencastro, Vanessa J De Paula and Maria Rita Passos-Bueno
    Citation: BMC Research Notes 2010 3:242
    Content type: Short Report Published on:

  15. Salmonid alphavirus (SAV) is a widespread pathogen in European aquaculture of salmonid fish. Distinct viral subtypes have been suggested based on sequence comparisons and some of these have different geographi...

    Authors: Marius Karlsen, Stephane Villoing, Karl F Ottem, Espen Rimstad and Are Nylund
    Citation: BMC Research Notes 2010 3:241
    Content type: Research article Published on:

  16. DNA methylation contributes to the regulation of gene expression during development and cellular differentiation. The recently developed Methylated DNA ImmunoPrecipitation (MeDIP) assay allows a comprehensive ...

    Authors: Jinsong Jia, Aleksandra Pekowska, Sebastien Jaeger, Touati Benoukraf, Pierre Ferrier and Salvatore Spicuglia
    Citation: BMC Research Notes 2010 3:240
    Content type: Short Report Published on:

  17. A large portion of tissues stored worldwide for diagnostic purposes is formalin-fixed and paraffin-embedded (FFPE). These FFPE-archived tissues are an extremely valuable source for retrospective (genetic) stud...

    Authors: Cornelis JJ Huijsmans, Jan Damen, Johannes C van der Linden, Paul HM Savelkoul and Mirjam HA Hermans
    Citation: BMC Research Notes 2010 3:239
    Content type: Technical Note Published on:

  18. Falls management programmes have been instituted to attempt to reduce falls. This pilot study was undertaken to determine whether the Nintendo® WiiFit was a feasible and acceptable intervention in community-dwell...

    Authors: Marie A Williams, Roy L Soiza, Alison McE Jenkinson and Alison Stewart
    Citation: BMC Research Notes 2010 3:238
    Content type: Short Report Published on:

  20. Major Histocompatibility Complex (MHC) has drawn the attention of evolutionary biologists due to its importance in crucial biological processes, such as sexual selection and immune response in jawed vertebrate...

    Authors: David Canal, Miguel Alcaide, Jarl A Anmarkrud and Jaime Potti
    Citation: BMC Research Notes 2010 3:236
    Content type: Technical Note Published on:

  23. Chronic complications of diabetes can be reduced through optimal glycemic and lipid control as evaluated through measurement of glycosylated hemoglobin (A1C) and low-density lipoprotein cholesterol (LDL-C). We...

    Authors: Helena Klomp, Roland F Dyck, Nirmal Sidhu, Paul J Cascagnette and Gary F Teare
    Citation: BMC Research Notes 2010 3:233
    Content type: Short Report Published on:

  25. The longitudinal epidemiology of major depressive episodes (MDE) is poorly characterized in most countries. Some potentially relevant data sources may be underutilized because they are not conducive to estimat...

    Authors: Scott B Patten
    Citation: BMC Research Notes 2010 3:231
    Content type: Project Note Published on:

  26. Hematologic manifestations of the human immunodeficiency virus (HIV) infection are a well-recognized complication of the disease and may be clinically important. Our objective was to determine the risk factors...

    Authors: José A Mata-Marín, Jesús E Gaytán-Martínez, Rosa E Martínez-Martínez, Carla I Arroyo-Anduiza, José L Fuentes-Allen and Moisés Casarrubias-Ramirez
    Citation: BMC Research Notes 2010 3:230
    Content type: Short Report Published on:

  27. Self-conscious emotions (shame, guilt and embarrassment) are part of many individuals' experiences of seeking STI testing. These emotions can have negative impacts on individuals' interpretations of the STI te...

    Authors: Myles Balfe, Ruairi Brugha, Diarmuid O' Donovan, Emer O' Connell and Deirdre Vaughan
    Citation: BMC Research Notes 2010 3:229
    Content type: Short Report Published on:

  29. Studies from iodine-sufficient areas have shown that a high proportion of patients taking medication for thyroid diseases have thyroid stimulating hormone (TSH) levels outside the reference range. Next to pati...

    Authors: Anke Hannemann, Nele Friedrich, Robin Haring, Alexander Krebs, Henry Völzke, Dietrich Alte, Matthias Nauck, Thomas Kohlmann, Hans-Christof Schober, Wolfgang Hoffmann and Henri Wallaschofski
    Citation: BMC Research Notes 2010 3:227
    Content type: Short Report Published on:

  30. MODELLER is a program for automated protein Homology Modeling. It is one of the most widely used tool for homology or comparative modeling of protein three-dimensional structures, but most users find it a bit ...

    Authors: Bhusan K Kuntal, Polamarasetty Aparoy and Pallu Reddanna
    Citation: BMC Research Notes 2010 3:226
    Content type: Technical Note Published on:

  31. The Asteraceae represents an important plant family with respect to the numbers of species present in the wild and used by man. Nonetheless, genomic resources for Asteraceae species are relatively underdevelop...

    Authors: Lucy Gonthier, Arnaud Bellec, Christelle Blassiau, Elisa Prat, Nicolas Helmstetter, Caroline Rambaud, Brigitte Huss, Theo Hendriks, Hélène Bergès and Marie-Christine Quillet
    Citation: BMC Research Notes 2010 3:225
    Content type: Short Report Published on:

  32. The innate immune system employs several receptor families that form the basis of sensing pathogen-associated molecular patterns. NOD (nucleotide-binding and oligomerization domain) like receptors (NLRs) compr...

    Authors: Marcel Kramer, Janne Boeck, Daniela Reichenbach, Christoph Kaether, Stefan Schreiber, Matthias Platzer, Philip Rosenstiel and Klaus Huse
    Citation: BMC Research Notes 2010 3:224
    Content type: Short Report Published on:

  33. Several high-density oligonucleotide microarray platforms are available for genome-wide single nucleotide polymorphism (SNP) detection and microarray-based comparative genomic hybridisation (array CGH), which ...

    Authors: Stine H Kresse, Karoly Szuhai, Ana H Barragan-Polania, Halfdan Rydbeck, Anne-Marie Cleton-Jansen, Ola Myklebost and Leonardo A Meza-Zepeda
    Citation: BMC Research Notes 2010 3:223
    Content type: Technical Note Published on:

  34. In animals mtDNA inheritance is maternal except in certain molluscan bivalve species which have a paternally inherited mitochondrial genome (genome M) along with the standard maternal one (genome F). Normally,...

    Authors: Eleni Kyriakou, Eleftherios Zouros and George C Rodakis
    Citation: BMC Research Notes 2010 3:222
    Content type: Short Report Published on:

  35. The first objective of a DNA microarray experiment is typically to generate a list of genes or probes that are found to be differentially expressed or represented (in the case of comparative genomic hybridizat...

    Authors: Emma Laing and Colin P Smith
    Citation: BMC Research Notes 2010 3:221
    Content type: Technical Note Published on:

  36. α-Santalol, an active component of sandalwood oil, has shown chemopreventive effects on skin cancer in different murine models. However, effects of α-santalol on cell cycle have not been studied. Thus, the obj...

    Authors: Xiaoying Zhang, Wei Chen, Ruth Guillermo, Gudiseva Chandrasekher, Radhey S Kaushik, Alan Young, Hesham Fahmy and Chandradhar Dwivedi
    Citation: BMC Research Notes 2010 3:220
    Content type: Research article Published on:

  37. The miR-200c/141 cluster has recently been implicated in the epithelial to mesenchymal transition (EMT) process. The expression of these two miRNAs is inversely correlated with tumorigenicity and invasiveness ...

    Authors: Rui Neves, Christina Scheel, Sandra Weinhold, Ellen Honisch, Katharina M Iwaniuk, Hans-Ingo Trompeter, Dieter Niederacher, Peter Wernet, Simeon Santourlidis and Markus Uhrberg
    Citation: BMC Research Notes 2010 3:219
    Content type: Short Report Published on:

  38. Anthroposophic medicine is a physician-provided complementary therapy system involving counselling, artistic and physical therapies, and special medications. The purpose of this analysis was to identify predic...

    Authors: Harald J Hamre, Claudia M Witt, Gunver S Kienle, Anja Glockmann, Stefan N Willich and Helmut Kiene
    Citation: BMC Research Notes 2010 3:218
    Content type: Research article Published on:

  40. Although altruism is a key principle in our current organ donation and transplantation system, the meanings and implications of the term have been widely debated. Recently, a new type of living organ donation-...

    Authors: Marie-Chantal Fortin, Marianne Dion-Labrie, Marie-Josée Hébert and Hubert Doucet
    Citation: BMC Research Notes 2010 3:216
    Content type: Short Report Published on:

  41. Clock family genes encode transcription factors that regulate clock-controlled genes and thus regulate many physiological mechanisms/processes in a circadian fashion. Clock1 duplicates and copies of Clock3 and...

    Authors: Marion I Paibomesai, Hooman K Moghadam, Moira M Ferguson and Roy G Danzmann
    Citation: BMC Research Notes 2010 3:215
    Content type: Research article Published on:

  42. SNP (Single Nucleotide Polymorphism) discovery is now routinely performed using high-throughput sequencing of reduced representation libraries. Our objective was to adapt 454 GS FLX based sequencing methodolog...

    Authors: Sophie Leroux, Katia Feve, Florence Vignoles, Olivier Bouchez, Christophe Klopp, Céline Noirot, David Gourichon, Sabine Richard, Christine Leterrier, Catherine Beaumont, Francis Minvielle, Alain Vignal and Frédérique Pitel
    Citation: BMC Research Notes 2010 3:214
    Content type: Technical Note Published on:

  43. The methylenetetrahydrofolate reductase (MTHFR) gene variant C677T has been implicated as a genetic risk factor in migraine susceptibility, particularly in Migraine with Aura. Migraine, with and without aura (...

    Authors: Annie Liu, Saraswathy Menon, Natalie J Colson, Sharon Quinlan, Hannah Cox, Madelyn Peterson, Thomas Tiang, Larisa M Haupt, Rod A Lea and Lyn R Griffiths
    Citation: BMC Research Notes 2010 3:213
    Content type: Short Report Published on:

  44. Southern China is a major area for endemic nasopharyngeal carcinoma (NPC). Genetic factors as well as environmental factors play a role in development of NPC. To investigate the roles of previously described c...

    Authors: Xiuchan Guo, Yi Zeng, Hong Deng, Jian Liao, Yuming Zheng, Ji Li, Bailey Kessing and Stephen J O'Brien
    Citation: BMC Research Notes 2010 3:212
    Content type: Research article Published on:

  45. The isolation of DNA-free RNA is a crucial step in the reverse transcription PCR (RT-PCR). Every RNA extraction procedure results in RNA samples contaminated with genomic DNA, which can cause false-positive ou...

    Authors: Lydia V Rump, Benedicta Asamoah and Narjol Gonzalez-Escalona
    Citation: BMC Research Notes 2010 3:211
    Content type: Technical Note Published on:

  46. Epithelial cells are exposed to a variety of mechanical stimuli. Epithelial Na+ channels (ENaC) mediate sodium transport across apical membranes of epithelial cells that line the distal nephron, airway and alveol...

    Authors: Alexey V Karpushev, Daria V Ilatovskaya and Alexander Staruschenko
    Citation: BMC Research Notes 2010 3:210
    Content type: Short Report Published on:

  47. Counselling on the danger signs of unpredictable obstetric complications and the appropriate management of such complications are crucial in reducing maternal mortality. The objectives of this study were to id...

    Authors: Malabika Sarker, Gerhard Schmid, Elin Larsson, Sylvia Kirenga, Manuela De Allegri, Florian Neuhann, Theodora Mbunda, Isaack Lekule and Olaf Müller
    Citation: BMC Research Notes 2010 3:209
    Content type: Short Report Published on:

  48. Many studies have been done to find out the molecular mechanism of systemic acquired resistance (SAR) in plants in the past several decades. Numbers of researches have been carried out in the model plants such...

    Authors: Jiyu Zhang, Xiaoli Du, Qingju Wang, Xiukong Chen, Dong Lv, Kuanyong Xu, Shenchun Qu and Zhen Zhang
    Citation: BMC Research Notes 2010 3:208
    Content type: Short Report Published on:

  49. The aim of this study was to evaluate the safety and efficacy of outpatient laparoscopic cholecystectomy (OLC) in a day surgery unit in a teaching hospital. OLC was offered to patients with symptomatic choleli...

    Authors: Athanasios Marinis, Emmanouil Stamatakis, Athanasia Tsaroucha, Nikolaos Dafnios, Georgios Anastasopoulos, Georgios Polymeneas and Theodosios Theodosopoulos
    Citation: BMC Research Notes 2010 3:207
    Content type: Short Report Published on:
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