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Table 4 Genes involved in the molecular function of the up regulated genes

From: Genetic profile of Egyptian hepatocellular-carcinoma associated with hepatitis C virus Genotype 4 by 15 K cDNA microarray: Preliminary study

Molecular Fuction Gene No. Gene Name
Protein Binding 28 MICA, SIPA1L1, SIN3A, VPS8, BTBD1, FBLN2, SUDS3, SYK, ARNT, RNF2, MYRIP, RIPK2, CBLB, SURF5, PHF3, NOTCH4, TNKS, LSM2(Bac-Bax), PSCD1, CBX3, MNAT1, RXPAP, FGFR1, ICEBERG(caspase-1-inhibitor), POP7, SMAD6, MYCBP2(MYC binding protein-2), SP110
Nucleotide binding 16 ABCG2, TNRC6B, SYK, MAP4K4, ATP6VIA, SPEN, MARK4, CUGBP2, CDK7, RAB14, MATR3, ATP2C1, FGFR1, RBM25, DYRK2, RIPK2
Metal ion binding 16 CHN1, RNF2, ADAMTS7, TCEA1, ATP6V1A, PLOD1, VPS8, PHF3, MYCBP2, MNAT1, MATR3, SP110, ZNF77, MYRIP, ZNF202, RXRA
Zinc ion binding 16 CHN1, RNF2, ADAMTS7, TCEA1, CBLB, VPS8, PHF3, MYCBP2, MNAT1, MATR3, SP110, ZNF77, MYRIP, ZNF202, MMP23B, RXPA
ATP binding 11 ABCG2, SKY, MAP4K4, ATP6V1A, MARK4, CDK4, DHX36, ATP2C1, FGFR1, DYRK2, RIPK2
Transferase activity 11 SYK, MAP4K4, HS2ST1, LYPLA3, MARK4, CDK7, FGFR1, DYRK2, RIPK2, GSTM4, TKT
Molecular Function unknown 10 WFDC1, FETUB, GPM6B, UBQLN4, PHF3, SURF5, PRCC, ZNF77, SIPA1L1, RXRA
Nucleic acid binding 9 EIF5A2, SND1, SPEN, POP7, LOC643641, MATR3, DHX36, RBM25, ZNF202
Calcium ion binding 9 GAS6, RCN1, CBLB, PPP3R1, FBLN2, ATP2C1, TKT, NOTCH4, CAPS
Hydrolase activity 7 LYPLA3, ITPA, TATDN2, POP7, DHX36, ATP6VIA, ATP2C1
DNA binding 6 SP110, TCEA1, SOX30, RNF2, ZNF77, SPEN
RNA binding 6 FNBP1, AKAP1, MATR3, LSM2, SPEN, CUGBP2