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Table 9 The correlation between the expression level of the studied genes and clinicopathological features of hepatocellular carcinoma cases

From: Genetic profile of Egyptian hepatocellular-carcinoma associated with hepatitis C virus Genotype 4 by 15 K cDNA microarray: Preliminary study

Reduced expression Over expression
Variable ISGF3G TNF-α VISA* CDK-7 NOTCH4 BAX
Total: 17 (%) 13 (76) 15 (88) 14 (82) 12 (70) 11 (64) 13 (76)
Age (Mean ± SD)
(57 ± 10.2)
      
< 57 = 10(59) 8(80) 9(90) 8(80) 7(70) 7 (70) 8(80)
> 57 = 7(41) 5(71) 6(85) 6(85) 5(71) 4 (57) 5(71)
Gender       
Male:13(76) 10(77) 12(92) 11(85) 10(77) 9(69) 11(85)
Female:4(24) 3(75) 3(75) 3(75) 2(50) 2(50) 2(50)
Tumor site       
Rirht = 11(65) 9(82) 10(90) 8(73) 7(64) 6(55) 9(82)
Left = 6(35) 4(66) 5(83) 6(100) 5(83) 5(83) 4(66)
Tumor size       
≤ 8 = 12(70) 10(83) 10(83) 11(91) 9(75) 8(66) 9 (75)
> 8 = 5(30) 3(60) 5(100) 3(60) 3(60) 5(100) 4 (80)
Grade       
I+II = 14(82) 10(71) 13(93) 12(85) 10(71) 8(57) 10(71)
III = 3(18) 3(100) 2(66) 2(66) 2(66) 3(100) 3(100)
Safety margin       
Pos 4 (24) 2(50) 3(75) 4(100) 3(75) 3(75) 3(75)
Neg 13(76) 11(85) 12(92) 10(77) 9(69) 8(61) 10(77)
Invasion       
Pos 9 (53) 7(77) 8(88) 8(88) 8(88) 9(100) 6(66)
Neg 8(47) 6(75) 7(87) 6(75) 4(50) 2(25) 7(87)
Cirrhosis       
Present: 10(59) 8(80) 9(90) 8(80) 7(70) 7(70) 9(90)
Absent: 7(41) 5(71) 6(85) 6(85) 5(71) 4(57) 4(57)
CAH       
Pos: 9 (53) 7(77) 8(88) 7(77) 6(66) 6(66) 8(88)
Neg: 8(47) 6(75) 7(87) 7(87) 6(75) 5(63) 5(63)
  1. *VISA (also known as MAVS, IPS-I or CARDIF)