From: Streptococcus pneumoniaeearly response genes to human lung epithelial cells
Function/gene name | Protein | TIGR4 genome acc. No. | Incubation time | |
---|---|---|---|---|
0.5 h | 1 h | |||
Cell envelope | ||||
cbpI a | choline binding protein I | SP0069 | 2.8 | |
cps4A | capsular polysaccharide biosynthesis protein Cps4A | SP0346 | 2.9 | |
cps4B | capsular polysaccharide biosynthesis protein Cps4B | SP0347 | 2.0 | |
cps4C | capsular polysaccharide biosynthesis protein Cps4C | SP0348 | 3.3 | |
cps4E | capsular polysaccharide biosynthesis protein Cps4E | SP0350 | 2.9 | |
cps4I | UDP-N-acetylglucosamine-2-epimerase | SP0357 | 2.4 | |
bgaA | β-galactosidase | SP0648 | 17.0 | |
nanA a | neuraminidase A, authentic frameshift | SP1693 | 16.5 | |
Energy metabolism | ||||
agaS | sugar isomerase domain protein AgaS | SP0065 | 5.6 | |
pyk | pyruvate kinase | SP0897 | -2.7 | |
glgA | glycogen synthase | SP1124 | 3.8 | |
acetoin dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase, putative | SP1162 | 2.7 | ||
zwf | glucose-6-phosphate 1-dehydrogenase | SP1243 | -2.7 | |
scrB | sucrose-6-phosphate hydrolase | SP1724 | 3.0 | 4.4 |
galT | galactose-1-phosphate uridylyltransferase | SP1852 | 2.7 | |
galK | galactokinase | SP1853 | 2.3 | |
recP | transketolase | SP2030 | -3.6 | |
arcA | arginine deiminase | SP2148 | 4.6 | |
gplK | glycerol kinase | SP2186 | 3.0 | |
Hypothetical proteins | ||||
conserved hypothetical protein | SP0024 | -2.6 | ||
hypothetical protein | SP0026 | -2.3 | ||
hypothetical protein | SP0052 | -3.5 | -5.6 | |
hypothetical protein | SP0067 | 2.4 | 2.1 | |
conserved hypothetical protein | SP0095 | -2.4 | ||
conserved hypothetical protein | SP0159 | -2.3 | ||
hypothetical protein | SP0190 | 2.3 | ||
hypothetical protein | SP0203 | -2.5 | ||
conserved hypothetical protein | SP0207 | -2.1 | ||
conserved hypothetical protein | SP0288 | -4.2 | -2.2 | |
conserved hypothetical protein | SP0742 | -2.9 | ||
conserved hypothetical protein | SP0951 | 2.4 | ||
conserved hypothetical protein | SP1003 | 2.1 | ||
hypothetical protein | SP1049 | 2.0 | ||
hypothetical protein | SP1059 | 4.4 | ||
conserved hypothetical protein | SP1174 | 2.4 | ||
hypothetical protein | SP1198 | 2.7 | 2.6 | |
hypothetical protein | SP1199 | 2.9 | 2.0 | |
conserved hypothetical protein | SP1601 | 2.4 | ||
hypothetical protein | SP1677 | 10.3 | ||
hypothetical protein | SP1678 | 2.9 | 6.1 | |
hypothetical protein | SP1679 | 4.6 | 9.6 | |
conserved hypothetical protein | SP1680 | 5.3 | 11.5 | |
hypothetical protein | SP2183 | 2.7 | 4.1 | |
Others | ||||
bacteriocin, putative | SP0109 | 2.3 | ||
lactose phosphotransferase system repressor, degenerate | SP0169 | 2.2 | ||
dihydropteroate synthase | SP0289 | -2.2 | -2.1 | |
acpP | acyl carrier protein | SP0418 | -2.0 | |
fabF | 3-oxoacyl-(acyl-carrier-protein) synthase II | SP0422 | -2.4 | |
accD | acetyl-CoA carboxylase, carboxyl transferase subunit beta | SP0426 | -2.4 | |
accA | acetyl-CoA carboxylase, carboxyl transferase subunit alpha | SP0427 | -3.4 | |
ilvB | acetolactate synthase, large subunit, biosynthetic type | SP0445 | -2.8 | |
zmpB | zinc metalloprotease ZmpB | SP0664 | -2.1 | |
ilvE | branched-chain amino acid aminotransferase | SP0856 | -2.0 | |
preprotein translocase, SecG subunit, putative | SP0974 | 2.5 | ||
asd | aspartate-semialdehyde dehydrogenase | SP1013 | -2.0 | |
bta | bacterocin transport accessory protein | SP1499 | -2.7 | -2.4 |
transcriptional regulator, MerR family | SP1856 | 2.0 | ||
groEL | chaperonin, 60 kDa | SP1906 | -2.4 | |
Protein synthesis | ||||
rpsD | ribosomal protein S4 | SP0085 | 2.7 | |
rpsJ | ribosomal protein S10 | SP0208 | 4.1 | |
rplW | ribosomal protein L23 | SP0211 | 2.9 | |
rpsC | ribosomal protein S3 | SP0215 | 2.0 | |
infA | translation initiation factor IF-1 | SP0232 | 2.4 | |
valS | valyl-tRNA synthetase | SP0568 | -2.1 | |
rplK | ribosomal protein L11 | SP0630 | 2.5 | |
infC | translation initiation factor IF-3 | SP0959 | 2.5 | |
rpml | ribosomal protein L35 | SP0960 | 3.9 | |
rpsR | ribosomal protein S18 | SP1539 | 2.8 | |
rpsF | ribosomal protein S6 | SP1541 | 2.9 | 3.0 |
rpmH | ribosomal protein L34 | SP1993 | 2.4 | |
rpmG | ribosomal protein L33 | SP2135 | 2.1 | |
yfiA | ribosomal subunit interface protein | SP2206 | -3.9 | |
Purine and pyrimidine ribonucleotide biosynthesis | ||||
purA | adenylosuccinate synthetase | SP0019 | -2.5 | |
purC a | phosphoribosylaminoimidazole-succinocarboxamide synthase | SP0044 | -5.1 | -4.7 |
purH | phosphoribosylaminoimidazolecarboxamide formyltransferase-IMP cyclohydrolase | SP0050 | -15.3 | -4.1 |
purE a | phosphoribosylaminoimidazole carboxylase, catalytic subunit | SP0053 | -6.4 | -8.5 |
purK a | phosphoribosylaminoimidazole carboxylase, ATPase subunit | SP0054 | -2.4 | |
nrdD | anaerobic ribonucleoside-triphosphate reductase | SP0202 | -4.4 | -4.3 |
nrdG | anaerobic ribonucleoside-triphosphate reductase activating protein | SP0205 | -3.4 | -2.8 |
thyA | thymidylate synthase | SP0669 | -2.2 | |
pyrK | dihydroorotate dehydrogenase, electron transfer subunit | SP0963 | -3.6 | |
nrdH | NrdH-redoxin | SP1178 | -2.1 | |
carB | carbamoyl-phosphate synthase, large subunit | SP1275 | -4.2 | |
pyrR | pyrimidine operon regulatory protein | SP1278 | -2.1 | -7.8 |
guaA a | GMP synthase | SP1445 | -2.4 | |
purR | pur operon repressor | SP1979 | -2.7 | -2.3 |
Transport | ||||
PTS system, IIA component | SP0064 | 2.2 | 3.4 | |
PTS system, mannose-specific IID component | SP0282 | -3.7 | ||
xanthine-uracil permease family protein | SP0287 | -8.4 | -5.3 | |
O-antigen transporter RfbX, putative | SP0356 | 2.5 | ||
PTS system, IIC component, putative | SP0647 | 4.3 | ||
sugar ABC transporter, ATP-binding protein | SP0846 | -2.1 | ||
ABC transporter, permease protein | SP1688 | 5.3 | ||
ABC transporter, permease protein | SP1689 | 2.8 | ||
ABC transporter, substrate-binding protein | SP1690 | 2.1 | ||
msmE | sugar ABC transporter, sugar-binding protein | SP1897 | 2.1 | |
malD | maltodextrin ABC transporter, permease protein | SP2110 | 2.6 | |
Unknown function | ||||
vanZ protein, putative | SP0049 | -2.9 | ||
ACT domain protein | SP0238 | -2.1 | -3.4 | |
HIT family protein | SP0521 | -2.4 | ||
gid | Gid protein | SP0943 | -2.2 | |
flavoprotein | SP1231 | -2.0 | ||
usp45 | secreted 45 kd protein | SP2216 | 2.1 |