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Figure 2 | BMC Research Notes

Figure 2

From: Cellular phosphatases facilitate combinatorial processing of receptor-activated signals

Figure 2

Phosphatase-dependent regulation provides for the generation of signal plasticity. Panels A, B and C depict the effect of silencing of either PP1 (), PP2A (), MKP3 (), MKP1 (□), MKP2 (■), SHP2 (), HePTP (▲), PP2B (), SHP1 () or PTP1B () on peak phosphorylation levels, initial phosphorylation rate and rate of de-phosphorylation respectively on representative examples, as compared to that obtained for cells treated with non-silencing siRNA (dashed line in panel A, or * in panels B and C).

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