Table 4 Association of ESR1 and APOE genetic polymorphisms and hypercholesterolemia

ESR1*

Alleles

S

87

14

1

1-1

X² = 6.391

L

77

30

2.421

1.242-4.72

df = 1

p = 0.011

Genotypes

SS

22

3

1

1-1

X² = 7.147

LS

43

8

1.364

0.3288-5.661

df = 2

LL

17

11

4.745

1.141-19.73

p = 0.028

APOE**

Alleles

ε2

21

1

1

1-1

X² = 11.46

ε3

123

32

5.463

0.6664-44.79

df = 2

ε4

14

11

16.5

1.366-199.2

p = 0.003

Genotypes

22

2

0

1

1-1

X² = 14.98

23

15

0

8.413e-006

8.413e-006-8.413e-006

df = 4

p = 0.004

24

2

1

1.285e+008

2.495e+007-6.62e+008

33

48

11

5.891e+007

2.27e+007-1.529e+008

34

12

10

2.1424+0088

7.876e+007-5.825e+008