Table 5 Haplotype analysis of three-SNP NOD1 haplotype in IBD patients and Caucasians in a New Zealand population.
Haplotype | Case subject frequency (%) | Control subject frequency (%) | p-value | OR (95% CI) | Global score statistics | |
|---|---|---|---|---|---|---|
CD | Three SNPs NOD1gregion | |||||
(rs2075818, rs2075822, rs2907748) | ||||||
CCA | 20.6 | 22.2 | 0.53 | 0.90 (0.67–1.21) | χ2 = 9.55, | |
CTG | 55.8 | 46.9 | 0.004 | 1.44 (1.12–1.85) | df = 3, | |
GTA | 3.3 | 4.2 | 0.25 | 0.77 (0.41–1.45) | p = 0.02 | |
GTG | 16.0 | 21.7 | 0.02 | 0.68 (0.50–0.92) | ||
UC | Three SNPs NOD1gregion (rs2075818, rs2075822, rs2907748) | |||||
CCA | 19.5 | 22.2 | 0.23 | 0.83 (0.62–1.11) | χ2 = 2.30, | |
CTG | 51.9 | 46.9 | 0.14 | 1.19 (0.93–1.52) | df = 3, | |
GTA | 3.8 | 4.2 | 0.79 | 0.89 (0.48–1.63) | p = 0.51 | |
GTG | 21.5 | 21.7 | 0.95 | 0.97 (0.72–1.30) |