Table 1 Baseline patient characteristics by level of medication adherence in the 6 months prior to enrollment (N = 2010)
Characteristic | Adherent (n = 1758) | Partially adherent (n = 36) | Non-adherent (n = 216) | p-value |
|---|---|---|---|---|
Age at baseline, mean ± SD years | 42.4 ± 11.0 | 38.5 ± 9.3 | 39.9 ± 11.6 | 0.007 |
Male, n (%) | 1075 (61.2) | 21 (58.3) | 135 (62.5) | 0.870 |
African American, n (%) | 651 (37.2) | 21 (58.3) | 77 (36) | 0.031 |
Schizoaffective diagnosis, n (%) | 583 (33.2) | 13 (36.1) | 66 (30.6) | 0.684 |
Illness duration, mean ± SD years | 21.7 ± 11.4 | 19.7 ± 10.0 | 20.3 ± 12.7 | 0.136 |
Uninsured, n (%) | 105 (6.1) | 5 (13.9) | 21 (10.0) | 0.020 |
PANSS total score, mean ± SD | 70.3 ± 18.6 | 72.2 ± 22.4 | 70.9 ± 17.1 | 0.593 |
Quality of Life Scale, total score, mean ± SD | 60.0 ± 22.3 | 58.9 ± 21.6 | 61.7 ± 22.4 | 0.781 |
Hospitalized at enrollment, n (%) | 52 (2.96) | 1 (2.78) | 23 (10.65) | < 0.001 |
Comorbid substance abuse disorder, n (%) | 483 (27.47) | 12 (33.33) | 78 (36.11) | 0.024 |
Comorbid personality disorder diagnosis, n (%) | 268 (15.24) | 2 (5.56) | 36 (16.67) | 0.228 |
Comorbid borderline intelligence/mental retardation, n (%) | 176 (10.01) | 5 (13.89) | 13 (6.02) | 0.118 |
Simpson-Angus total score, mean ± SD | 4.34 ± 4.08 | 4.00 ± 4.17 | 4.15 ± 4.08 | 0.547 |
AIMS total score, mean ± SD | 3.35 ± 4.13 | 2.94 ± 3.73 | 2.51 ± 3.14 | 0.137 |