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Table 2 Performance comparison of different methods on a simulated large-scale dataset.

From: AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm

Methods True positive rate False discovery rate
SNPHarvester 26.5% 98.6%
Generic ACO 0 100%
AntEpiSeeker 66.7% 97.1%
AntEpiSeeker with minimized false positives 52.3% 18.8%