Suppressor of cytokine signaling 3 (SOCS3) is not an independent biomarker of colorectal adenoma risk

BMC Research Notes

Table 1 Descriptive Characteristics of Study Participants

Variable	Case (n = 93)	Control (n = 229)	p-value *
Age median (1^st, 3^rd quartile)**	58 (51, 56)	55 (50, 63)	0.03
Race-White N (%)†	73 (78)	177 (77)	0.88
Sex-Male N (%)	51 (55)	85 (37)	0.004
WHR median (1^st, 3^rd quartile)	0.922 (0.854, 1.000)	0.888 (0.804, 979)	0.04
Family History of CRC - N (%)	16 (20)	31 (15)	0.37
Plasma IL-6 median (1^st, 3^rd quartile)	0.21 (0.00, 0.56)	0.07 (0.00, 0.41)	0.01
Plasma TNFα median (1^st, 3^rd quartile)	1.93 (1.44, 2.74)	1.75 (1.30, 2.44)	0.14
Plasma CRP median (1^st, 3^rd quartile)	3,959 (1,934, 14,278)	7,239 (2,294, 16,728)	0.14
Tissue SOCS3 median (1^st, 3^rd quartile)	3.09 (2.33, 3.77)	3.09 (2.35, 3.80)	0.77

* P-values are from Fishers Exact Test for categorical variables and Mann-Whitney test to compare medians for continuous variables.
** Standard error (se); Waist Hip Ratio (WHR); Suppressor of Cytokine Signaling 3 (SOCS3)
† Percentages within columns

ISSN: 1756-0500