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Table 1 miRNAs with altered expression after ATRA induced differentation in NB4 cells by microarray analysis.

From: Non-coding RNAs change their expression profile after Retinoid induced differentiation of the promyelocytic cell line NB4

Name P-value NB4 expression NB4 + ATRA expression Map TvsUT Validation Densitometry
hsa-mir-017-precNo2 0,0447 2,944 1,388 13q31 Down down 6.0 fold
hsa-mir-186-prec 0,0447 0,864 0,891 1p31 Up up 0.5 fold
hsa-mir-193-precNo1 0,0385 1,031 0,847 17q11.2 Down down 1.2 fold
hsa-mir-195-prec 0,0373 2,618 1,954 17p13 Down down 0.8 fold
hsa-mir-025-prec 0,0351 7,56 3,157 7q22 Down down 4.1 fold
hsa-let-7a-1-prec 0,0243 0,962 0,889 9q22.2 Down up 3.2 fold
hsa-mir-215-precNo2 0,0104 0,691 0,792 1q41 Up up 0.5 fold
hsa-mir-223-prec 0.0232 8.68 17.08 Xq12-13.3 Up up 10.6 fold
  1. In the table are showed for each miRNA the name (hsa = human miRNAs), the P-value, the normalization of two independent experiment (NB4 = untreated; NB4-ATRA = treated); the locus map (map); the expression in treated versus untreated cells (T vs UT) and the expression (T vs UT) after northen blot validation (validation: up = upregulation; down = downregulation); the densitometry shows the average of three independent experiments.