Table 2 Clinical performance of AAG and DCP at specificity of 95%
From: Alpha-1-acid glycoprotein as potential biomarker for alpha-fetoprotein-low hepatocellular carcinoma
Marker | Cut-off | Sensitivity | Accuracy | PPV | NPV |
|---|---|---|---|---|---|
All HCC (n = 124) | |||||
AAG | 800 | 71 | 82 | 95 | 72 |
DCP | 4.5 | 74 | 83 | 95 | 74 |
AFP-low HCC (n = 61) | |||||
AAG | 800 | 82 | 90 | 91 | 89 |
DCP | 4.5 | 57 | 80 | 88 | 78 |
AFP-high HCC (n = 63) | |||||
AAG | 800 | 62 | 82 | 89 | 79 |
DCP | 4.5 | 90 | 93 | 92 | 94 |