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Table 2 Clinical performance of AAG and DCP at specificity of 95%

From: Alpha-1-acid glycoprotein as potential biomarker for alpha-fetoprotein-low hepatocellular carcinoma

Marker Cut-off Sensitivity Accuracy PPV NPV
All HCC (n = 124)     
AAG 800 71 82 95 72
DCP 4.5 74 83 95 74
AFP-low HCC (n = 61)     
AAG 800 82 90 91 89
DCP 4.5 57 80 88 78
AFP-high HCC (n = 63)     
AAG 800 62 82 89 79
DCP 4.5 90 93 92 94
  1. PPV, positive predictive value; NPV, negative predictive value; HCC, hepatocellular carcinoma; AAG, α-1-acid glycoprotein; DCP, des-γ-carboxy prothrombin; AFP, α-fetoprotein