Cancer | Sprawl |
---|---|
Fractal growth pattern limited by natural barriers. | Fractal growth pattern limited by natural and man-made barriers |
Initiation by growth factors and altered cell signaling | Initiated by profit-based speculative development |
Loss of p53 function | Low cost gasoline |
Loss of cellular differentiation, expansion of clonal populations | Segregated land use and loss of differentiated architecture |
Critical need for angiogenesis, often conducted poorly by tumors | Powerful effects of road development, often constructed in an inefficient manner |
Cachexia and Infection | Urban blight |