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Table 2 Mean impedance values (in ohm (Ω)) comparing 200 mg and 500 mg oral and 500 mg intravenous aspirin dosages

From: Is there an ideal way to initiate antiplatelet therapy with aspirin? A crossover study on healthy volunteers evaluating different dosing schemes with whole blood aggregometry

  Aspirin 200 mg oral Aspirin 500 mg oral Aspirin 500 mg i.v. P-value (200 mg vs. 500 mg oral)
Day 1 (0 min) 13.2 (11.7 - 14.6) 13.6 (10.8 - 16.4) 15.3 (14.0 - 16.7) 0.80
5 min 12.8 (9.9 - 15.6) 12.8 (10.2 - 15.4) 0.0 0.96
10 min 12.3 (9.4 - 15.1) 11.8 (7.6 - 16.1) 0.0 0.87
15 min 9.3 (5.4 - 13.3) 8.3 (4.4 - 12.1) 0.2 (-0.4 - +0.8) 0.68
30 min 3.8 (0.6 - 6.9) 4.2 (0.5 - 7.8) 0.0 0.87
45 min 3.8 (0.4 - 7.3) 2.6 (-0.05 - 5.2) 0.25 (-0.5 - +1.0) 0.52
60 min 3.9 (0.06 - 7.8) 1.3 (-0.3 - 2.9) 0.2 (-0.4 - +0.8) 0.17
120 min 3.2 (-0.6 - 6.9) 1.3 (-0.6 - 3.1) 0.2 (-0.4 - +0.8) 0.30
180 min 1.8 (-0.6 - 4.1) 1.3 (-0.6 - 3.3) 0.0 0.69
240 min 2.1 (-0.4 - 4.6) 0.7 (-0.8 - 2.1) 0.2 (-0.4 - +0.8) 0.11
Day 2 (0 min) 3.0 (0.6 - 5.4) 3.3 (-1.0 - 7.7) 0.6 (-0.5 - +1.6) 0.89
  1. Data presented are mean and 95% confidence interval. Significance was tested by using the paired student's t test under the Bonferroni-adjusted significance level of p = 0.0045 (= 0.05/11) for multiple comparisons.