Association of beta3-adrenergic receptor (ADRB3) Trp64Arg gene polymorphism with obesity and metabolic syndrome in the Balinese: a pilot study

Table 2 Association of the Arg allele with BMI and WC in urban and rural

Variables	Classification	Urban				Rural					Trp64	Arg64
		Total (%)	Trp64 (%)	Arg64 (%)	p (Trp64 vs Arg64)	Total (%)	Trp64 (%)	Arg64 (%)	p (Trp64 vs Arg64)	p (Urban vs Rural)	p (Urban vs Rural)	p (Urban vs Rural)
All, n		282	249	33		246	220	26
BMI	Underweight	3	3	0	0.522	16	18	0	0.136	<0.001	<0.001	0.433
	Normal	24	24	27		41	41	42
	Overweight	22	22	21		18	18	19
	Obese I	37	38	30		20	19	31
	Obese II	14	13	21		4	4	8
WC	Abdominal obesity	62	61	67	0.561	36	34	58	0.016	<0.001	<0.001	0.479
	Non abdominal obesity	38	39	33		64	66	42
Male, n		175	155	20		128	113	15
BMI	Underweight	2	2	0	0.234	13	15	0	0.088	<0.001	<0.001	0.052
	Normal	24	24	25		44	42	53
	Overweight	16	16	15		16	19	0
	Obese I	40	43	25		22	20	40
	Obese II	18	15	35		5	4	7
WC	Abdominal obesity	56	55	60	0.702	30	28	40	0.352	<0.001	<0.001	0.241
	Non abdominal obesity	44	45	40		70	72	60
Female, n		107	94	13		118	107	11
BMI	Underweight	5	5	0	0.699	20	21	0	0.129	<0.001	<0.001	0.496
	Normal	24	23	31		37	38	27
	Overweight	31	31	31		20	18	45
	Obese I	33	32	38		19	19	18
	Obese II	7	8	0		4	4	9
WC	Abdominal obesity	72	71	77	0.671	43	39	81	0.007	<0.001	<0.001	0.769
	Non abdominal obesity	28	29	23		57	61	9

BMI: body mass index, WC: waist circumference. BMI classification according to the classification of the Asia-Pacific perspective redefining obesity in adult Asian were: underweight < 18.5 kg/m², normal 18.5-22.9 kg/m²; overweight at risk 23-24.9 kg/m²; obese I 25-29.9 kg/m²; obese II ≥ 30 kg/m² [17]. Abdominal obesity was based on waist circumference if ≥ 90 cm in male or ≥ 80 cm in female [17]. All p-values were calculated using the Chi-square test.

ISSN: 1756-0500