Association of beta3-adrenergic receptor (ADRB3) Trp64Arg gene polymorphism with obesity and metabolic syndrome in the Balinese: a pilot study

Table 3 Association of the Arg allele with MetS in urban and rural

Variables	Classification	Urban				Rural					Trp64	Arg64
		Total (%)	Trp64 (%)	Arg64 (%)	p (Trp64 vs Arg64)	Total (%)	Trp64 (%)	Arg64 (%)	p (Trp64 vs Arg64)	p (Urban vs Rural)	p (Urban vs Rural)	p (Urban vs Rural)
All, n		282	249	33		246	220	26
MetS	MetS	33	32	33	0.926	18	17	23	0.465	<0.001	<0.001	0.388
	Non MetS	67	68	67		82	83	77
Male, n		175	155	20		128	113	15
MetS	MetS	40	39	45	0.628	16	16	13	0.795	<0.001	<0.001	0.046
	Non MetS	60	61	55		84	84	87
Female, n		107	94	13		118	107	11
MetS	MetS	21	21	15	0.622	20	19	36	0.166	0.967	0.647	0.237
	Non MetS	79	79	85		80	81	64

MetS: metabolic syndrome. MetS criteria were: elevated waist circumference (≥ 90 cm in men and ≥ 80 cm in women), elevated triglycerides (≥ 150 mg/dl or 1.7 mmol/l) or drug treatment for elevated triglyceride, reduced HDL-C (< 40 mg/dl or 1.0 mmol/l in males and < 50 mg/dl or 1.3 mmol/l) in females or drug treatment for reduced HDL-C, elevated blood pressure (systolic ≥ 130 or diastolic ≥ 85 mmHg) or antihypertensive drug treatment in a patient with a history of hypertension, and elevated fasting plasma glucose (≥ 100 mg/dl) or drug treatment for elevated glucose [18]. All p-values were calculated using the Chi-square test.

ISSN: 1756-0500