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Table 2 Association (adjusted odds ratio, OR, with 95% confidence interval, CI) of low avidity HPV16 antibodies with increased risk of being seropositive for other HPV types among Finnish and Ugandan women.

From: Low avidity of human papillomavirus (HPV) type 16 antibodies is associated with increased risk of low-risk but not high-risk HPV type prevalence

Population

Seropositivity

OR1(95% CI)

OR2(95% CI)

OR3(95% CI)

Finland (n = 248)

HPV16 only

1

1

1

 

HPV16 + 6 or 11

1.1 (0.4-2.8)

1.9 (0.6-6.1)

0.8 (0.1-6.8)

 

HPV + 31 or 33

0.3 (0.1-1.0)

0.3 (0.1-1.3)

0.8 (0.0-1.0)

 

HPV + 18 or 45

0.7 (0.2-1.8)

0.5 (0.1-2.0)

0.3 (0.2-3.8)

Uganda (n = 117)

HPV16 only

1

1

1

 

HPV16 + 6 or 11

3.5 (1.3-9.7)

3.0 (1.1-8.5)

2.9 (1.0*-8.4)

 

HPV + 31 or 33

0.8 (0.2-2.9)

0.7 (0.2-2.5)

0.6 (0.2-2.3)

 

HPV + 18 or 45

0.6 (0.1-3.0)

0.5 (0.1-2.9)

0.5 (1.0-2.8)

  1. Cutoff_30% = using low avidity controls mean plus 3 standard deviations
  2. OR1 = adjusted for age
  3. OR2 = adjusted for age, Chlamydia trachomatis, HIV
  4. OR3 = adjusted for age, C. trachomatis, HIV and smoking
  5. *1.0 = lower 95% confidence limit 1.01