Skip to main content

Table 2 Differential Features between Spermatocytic and Classical Seminoma

From: Spermatocytic seminoma at the National Institute of Oncology in Morocco

  Classical seminoma SS
incidence 2% 40%
Usual age on presentation (yrs) 20-50 ≥ 50 ans
Occurrence in undescended testis (%) 8-10% No documented case
Site Testis only Testis, ovary, mediastinurn, retroperitoneum and pineal region
Cell types one 3 types: small lymphocyte-like, intermediate-sized and large cells
lymphocytic infiltration Rare ou absent Present, may be abundant
DNA ploidy Aneuploid Diploid, Hyperdiploid
intratubular component Typical IGCN(intratubular germ cell neoplasia) Infiltrating component spermatocytic seminoma
metastases Metastases common 3 cases
PLAP positive Negative
prognosis Stage depending Excellent. Better than classical seminoma
  1. PLAP: immunohistochemistry for placental alkaline phosphatase;