Table 2 Differential Features between Spermatocytic and Classical Seminoma
From: Spermatocytic seminoma at the National Institute of Oncology in Morocco
| Â | Classical seminoma | SS |
|---|---|---|
incidence | 2% | 40% |
Usual age on presentation (yrs) | 20-50 | ≥ 50 ans |
Occurrence in undescended testis (%) | 8-10% | No documented case |
Site | Testis only | Testis, ovary, mediastinurn, retroperitoneum and pineal region |
Cell types | one | 3 types: small lymphocyte-like, intermediate-sized and large cells |
lymphocytic infiltration | Rare ou absent | Present, may be abundant |
DNA ploidy | Aneuploid | Diploid, Hyperdiploid |
intratubular component | Typical IGCN(intratubular germ cell neoplasia) | Infiltrating component spermatocytic seminoma |
metastases | Metastases common | 3 cases |
PLAP | positive | Negative |
prognosis | Stage depending | Excellent. Better than classical seminoma |