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Table 1 Identified polymorphisms in porcine TFRC, ACK1, MUC4, MUC20 and KIAA0226 genes

From: Characterisation of five candidate genes within the ETEC F4ab/ac candidate region in pigs

Gene

No.

Base

Consequence

TFRC (100.8 Mb)

1

G→A (E4)

Ala→Thr

 

2

T→C (E10)

Silent

 

3

G→T (I11)

10 bp before branch point

ACK1 (100.9 Mb)

4

C→G (E1)

Pro→Ala

 

5

T→C (E2)

Silent

 

6

G→T (E2)

Silent

 

7

C→T (E3)

Silent

 

8

A→C (E7)

Silent

 

9

C→T (E7)

Silent

 

10

T→C (E9)

Silent

 

11

C→T (E9)

Silent

 

12

G→A (E10)

Silent

 

13

C→A (E12)

Pro→His

 

14

A→G (E12)

Silent

 

15

G→A (E12)

Silent

 

16

G→A (E12)

Val→Met

 

17

A→G (E12)

Silent

 

18

G→A (E12)

Arg→His

 

19

G→C (E12)

Ser→Thr

 

20

C→G (I14)

5 bases before exon 15

MUC4 (101.0 Mb)

21

C→A (E12)

Silent

 

22

C→T (I13)

4 bases before exon 14

 

23

C→T (I13)

16 bases before exon 14

 

24

C→T (I13)

28 bases before exon 14

 

25

C→T (E19)

Silent

 

26

G→A (E24)

Gly→Ser

 

27

T→C (E24)

Silent

 

28

G→A (3UTR)

187 bases after TGA

 

29

G→A (3UTR)

259 bases after TGA

MUC20 (101.1 Mb)

30

A→C (3UTR)

201 bases after TGA

 

31

C→T (I2)

58 bases after exon 2

 

32

C→T (E2)

Silent

 

33

A→T (E1)

Silent

KIAA0226 (101.1 Mb)

34

C→T (E20)

Silent

  1. A total of 34 polymorphisms were identified in the four tested animals (2 resistant Wild Boars and 2 homozygous susceptible Large White sows). Gene names are shown in the first column (gene positions at chromosome 13 in Sscrofa 9 are in brackets), polymorphisms in the second column and E and I in brackets indicate exonic (E) or intronic (I) location of the polymorphisms. The third column shows the nature of the polymorphisms. The six polymorphisms matching the ETEC F4ab/ac genotype perfectly in the four animals are in bold, and the two polymorphisms underlined are also closely associated with the ETEC F4ab/ac status in the additional 42 animals.