Skip to main content

Advertisement

Table 1 List of genes down regulated upon Cyclin T2 and Cyclin T1 depletion

From: Limited redundancy in genes regulated by Cyclin T2 and Cyclin T1

Gene name Gene ID Gene identifier Probe ID Chromosome Fold-change p-value
Top 10 genes down-regulated by Cyclin T2 depletion
Heat shock 27 kDa protein 3 HSPB3 NM_006308 206375_s_at 5 -3.12 0.0368
G protein-coupled receptor 137B GPR137B NM_003272 204137_at 1 -2.3 0.0251
ATP-binding cassette, sub-family A (ABC1), member 1 ABCA1 NM_005502 203504_s_at 9 -2.1 0.0336
Ankyrin repeat domain 12 ANKRD12 X80821 216563_at 18 -2.06 0.0166
Ataxin 1 ATXN1 AW235612 203231_s_at 6 -2.04 0.0111
Coronin 6 CORO6 NM_032854 1552301_a_at 17 -2.04 0.0330
Growth arrest-specific 1 GAS1 NM_002048 204457_s_at 9 -2.02 0.0303
ATG16 autophagy related 16-like 1(S. cerevisiae) ATG16L1 NM_017974 220521_s_at 2 -1.95 0.0375
Hexamethylene bis-acetamide inducible 1 HEXIM1 NM_006460 202815_s_at 17 -1.94 0.0482
Calcium channel, voltage-dependent, beta 2 subunit CACNB2 NM_000724 207776_s_at 10 -1.85 0.0178
Top 10 genes down-regulated by Cyclin T1 depletion
Chemokine (C-X-C motif) ligand 14 CXCL14 NM_004887 218002_s_at 5 -3.55 0.0403
Transmembrane protease, serine 3 TMPRSS3 AB038160 223949_at 21 -2.59 0.0361
Ankyrin repeat domain 29 ANKRD29 AI307802 238332_at 18 -2.36 0.0433
FK506 binding protein 1B, 12.6kDa FKBP1B NM_004116 206857_s_at 2 -2.16 0.0108
Syndecan binding protein (syntenin) SDCBP NM_005625 203231_s_at 8 -2.09 0.0366
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 DDX18 NM_006773 205763_s_at 2 -1.9 0.0217
Eukaryotic translation initiation factor 4E binding protein 2 EIF4EBP2 U88989 224653_at 10 -1.89 0.0168
Serine/threonine kinase 38 STK38 NM_007271 1553117_a_at 6 -1.68 0.0196
Cyclin G2 CCNG2 AW134535 202769_at 4 -1.65 0.0129
S100 calcium binding protein A4 S100A4 NM_002961 203186_s_at 1 -1.62 0.0117
  1. Genes with greatest down regulation specific to Cyclin T2 or Cyclin T1 depletion. The 10 genes with greatest decrease in expression following Cyclin T2 or Cyclin T1 depletion are listed (p 0.05). All fold-changes are relative to MM control. Minimum expression level of genes in MM control was arbitrarily chosen as 3.0.