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Table 1 Comparison of hypertensive patients on monotherapy versus combination antihypertensive therapy

From: Spectrum of antihypertensive therapy in South Asians at a tertiary care hospital in Pakistan

Characteristics Overall Mono therapy dual therapy > 3 drugtherapy P value*
  %(n)
N = 1132**
%(n)
41.2(491)
%(n)
32.2(384)
%(n)
14.8(176)
 
Age(years)
mean (SD)
62.5(12.47) 62.8(12.3) 62.2(12.4) 62.5(12.6) 0.75
Age groups(years)
18-39
3.3(39) 43.6(17) 28.2(11) 28.2(11)  
40-59 33.8(402) 39.1(157) 36.3(146) 24.6(99)  
≥60 62.8(748) 42.2(316) 30.3(227) 27.4(205) 0.33
Gender
males
45.3(540) 42.1(216) 32.4(166) 29.3(158) 0.14
Comorbids conditions
Diabetes 46.3(551) 41.2(219) 34.0(181) 27.4(151) 0.62
Chronic kidney disease 8.9(106) 34.6(36) 38.5(40) 28.3(30) 0.25
Ischemic heart disease 34.9(416) 33.6(137) 36.3(148) 31.5(131) < 0.001
Stroke 11.6(138) 41.4(55) 36.1(48) 25.4(35) 0.9
Chronic liver disease 4.7(56) 41.8(23) 34.5(19) 25(14) 0.91
Systolic Blood pressure
mean (SD)
136.2(25) 136.2(23.98) 135.6(25.05) 136.8(27.2) 0.8
Diastolic blood Pressure
mean (SD)
77.66(14) 77.7(12.90) 77.4(14.28) 77.7(16.5) 0.9
  1. *p value < 0.05 is significant; it is for the groups(monotherapy,2 drug therapy and ≥3 drug therapy)
  2. **59 patients had missing records for comorbids
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