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Figure 2 | BMC Research Notes

Figure 2

From: Gene expression profiling of oxidative stress response of C. elegans aging defective AMPK mutants using massively parallel transcriptome sequencing

Figure 2

Comparison of gene expression level changes against oxidative stress between wild type and aak-2 mutants. (A) Correlation between gene expression level changes of all genes identified in stressed wild type and stressed aak-2 mutants relative to unstressed wild type. (B) Correlation between gene expression level changes of genes significantly up or down-regulated commonly in stressed wild type and stressed aak-2 mutants relative to unstressed wild type (green). The commonly up or down-regulated genes in stressed wild type and stressed aak-2 mutants show much higher correlation compared to all genes indicating these genes are not only commonly regulated in wild type and aak-2 mutants against oxidative stress, but also the degree of the expression level changes is overall quite similar. The commonly up or down-regulated genes in stressed wild type and stressed aak-2 mutants and their expression level changes in unstressed aak-2 mutants (orange). A large group of collagens are commonly up-regulated in stressed wild type and stressed aak-2 mutants, but insignificantly changed in unstressed aak-2 mutants as indicated.

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