Pathway size by gene | Pathway overlapping | Gene mapping to pathway |
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Range | Proportion | Range | Proportion1 | Range | Proportion |
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> = 10, < 20 | 36% | 0 | 84% | Unique | 26.20% |
> = 20, < 100 | 55% | > 0, < 0.01 | 2.10% | > = 2, < 10 | 58.50% |
> = 100, < 200 | 7.70% | > 0.01, < 0.1 | 11.30% | > = 10, < 100 | 15.10% |
> = 200, < 300 | 1.30% | > 0.1, < 0.5 | 2.50% | > = 100 | 0.20% |
 |  | > 0.5 | 0.10% |  |  |
- Note 1: consider all possible pairs from of 854 canonical pathways; define the ratio as sharing count of genes out of all different genes for one pair of pathways (union overlap).
- A survey on 854 selected candidate pathways was conducted in order to investigate the characteristics of pathway size, pair-wise pathway overlap and gene allocation. Pathway size was measured by number of genes contained in the pathway; pathway overlapping was defined by the union overlapping ratio for one pair of pathways; gene allocation was counted as the number of pathways the genes belong to.