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Table 2 The consequence of 454 antibody sequencing errors affecting the functionality of antibodies as determined by IMGT/HighV-QUEST using sequence data obtained from the two repeat 454 runs, 1 and 2.
From:
454 antibody sequencing - error characterization and correction
Productive
65.8 (16.1)a
68 (23)a
Unproductive
13.7
5.3
Stop codon
3.7
3.1
No rearrangement
0.6
0.5
Functionality
Run 1 (%)
Run 2 (%)
Productive
65.8 (16.1)a
68 (23)a
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