Table 6 Functional categories of the genes listed in Table 5
From: Computational analysis of expression of human embryonic stem cell-associated signatures in tumors
Functional categories | Representative genes |
|---|---|
Cell cycle regulation | ORC2, NCAPH, DSCC1, CDC25A, CDC25B, CKS2, CKS1B, BUB3, CCND2, CCNB1, DLGAP5 |
DNA repair/replication | TOP2A, MCM4, MCM6, RFC4, PCNA, PPIA, HMGB2, H2AFX, PRKDC |
Apoptosis | FAS, BAK1, IFI16, PHF17, BTG2, PSMB2, BCL2, APC, TP53 |
Development/differentiation | ETV4, FGFR1, FGFR2, VCAN, STAT3, HHEX, EPHB1, NTRK2, GPM6B, TGFB3, BMI1, SOX2, DNMT3B, SOX4 |
Cell adhesion | VCAN, CD9, CD44, CD47, NCAM1, COL6A3, PODXL, FN1 |
TF activity | GATA2, TMF1, STAT1, STAT3, MAF, FUBP1, MYB, NFYC, TGIF1, SOX2, ZEB2, TAF12, ZFP36L1, MLLT10, MYST3, TCF4, TCF12, ETV4, MYBL2 |