Table 1 In vitro antiplasmodial activity, cytotoxicity, and selectivity index of the plant extracts
From: In vitro antiplasmodial activity of crude extracts of Tetrapleura tetraptera and Copaifera religiosa
Plants species | Voucher number | Extract | Antiplasmodial activity (IC50, μg/ml)a | Cytotoxicity MRC-5 | Selectivity Indexc | ||
|---|---|---|---|---|---|---|---|
|  |  |  | FCB | 3D7 | (CC50 μg/ml)b | FCB | 3D7 |
Copaifera religiosa | D. N. 584 | CH2Cl2 | 13.4 ± 3.6 | 8.5 ± 4.7 | 4.87 ± 0.5 | 0.37 | 0.61 |
|  |  | CH3OH | 500.7 ± 16.4 | 480.9 ± 34.2 | NT | ND | ND |
Tetrapleura tetraptera | J.J. WIE 6388 | CH2Cl2 | 10.1 ± 3.2 | 13.0 ± 5.1 | 79.9 ± 24.3 | 7.91 | 6.15 |
|  |  | CH3OH | 34.6 ± 4.7 | 29.6 ± 6.9 | 89.4 ± 10.8 | 2.58 | 3.02 |
Chloroquine |  |  | 324.8 ± 16.8 nM | 7.9 ± 2.3 nM |  |  |  |