Integration of gene expression data with prior knowledge for network analysis and validation

BMC Research Notes

Table 1 The filtered networks' sizes.

Network	Data	Strict			1-extended
		# V	# E	# WCC	# V	# E	# WCC
Signaling	Ref.	1843	3931	54
	Filtered	609	770	168	1410	2564	43
Metabolic	Ref.	1793	5711	21
	Filtered	172	225	71	1091	1983	16

This table shows the two reference networks (Ref.) and their filtered sub-networks with their number of vertices (# V), number of edges (# E) and their number of weakly connected components (# WCC). The expression data was obtained from experiments comparing breast cancer with normal breast tissue. The number of weakly connected components is reduced drastically between strict and 1-extended filtering.

ISSN: 1756-0500