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Table 1 Baseline assessment of NESDO

From: The Netherlands study of depression in older persons (NESDO); a prospective cohort study

Topic Measurement instrument
Demographics: Age, gender, education, SESa, religion, partner status, family Standard questions
Diagnostics Composite Interview Diagnostic Instrument (CIDI) -version 2.1 World Health Organization (WHO), 1997: depressive and anxiety disorders
- Depression, severity Inventory of Depressive Symptoms (IDS; Rush et al., 1996,
- Apathy, severity Apathy Scale (Starkstein et al., 1992)
- Anxiety symptoms Beck Anxiety Index (Beck et al., 1988)
Physical conditions
- Chronic diseases LASAa Questionnaire (Kriegsman et al., 1996)
- Pain Chronic Graded Pain Scale (Von Korff & Miglioretti, 2005)
- Vision and hearing LASAa Questionnaires
- Sleep Insomnia Rating Scale (Levine et al., 2003)
- Functional limitations WHO-Disability Assessment Scale (Chwastiak et al., 2003)
- Medication use Registration of medication use
- Smoking & drugs Past & current smoking questions
- Alcohol dependency Alcohol Use Disorders Identification Test (Babor et al., 1989)
- Physical Activities International Physical Activities (Craig et al., 2003)
Biological determinants
- Inflammation markers, BDNFa & polymorphism Fasting blood sample
- Autonomic Nervous System Electrocardiography & impedance cardiography (VU-AMS; de Geus et al., 1995)
- Cortisol 6 saliva samples, including Dexamethasone Suppression Test (Wüst et al., 2000; APA 1986)
Psychol. determinants
- Personality: Big Five NEO-Five Factor Inventory (Costa & McCrae, 1995)
- Mastery Pearlin Mastery scale (Pearlin & Schooler 1978)
- Daily Hassles Worry Scale-R (Wisocki, 1986)
Social determinants
- Early life events NEMESIS questionnaire (De Graaf et al., 2004)
- Recent life events Brugha Questionnaire (Brugha et al., 1985)
- Loneliness and affiliation Loneliness and affiliation scale (De Jong Gierveld & Kamphuis, 1995)
- Social support Close Person Inventory (CPI; Stansfeld et al., 1992)
Cognitive functioning
- Global cognitive functioning Mini-Mental State Examination (Folstein et al. 1975)
- Executive functioning Stroop Color-Word test (short form) (Stroop 1935)
- Motivational problems Digit Span (subtest WAISa) (Wechsler, 1958)
- Memory function Auditory Verbal Learning Test (Rey, 1964; van der Elst et al. 2005)
Use of Care Trimbos/iMTA questionnaire for Costs associated with Psychiatric Illness (Hakkaart-van Roijen, 2002)
  1. a SES Social Economic Status; LASA Longitudinal Aging Study Amsterdam; BDNF brain-derived neurotrophic factor; WAIS Wechsler Adult Intelligence Scale