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Figure 2 | BMC Research Notes

Figure 2

From: Baclofen alters gustatory discrimination capabilities and induces a conditioned taste aversion (CTA)

Figure 2

Experiment 2-CTA Acquisition. Mean ml SAC. Consumption (± SEM) on the Final Acquisition Trial. All animals that received either SAC + LiCl or SAC + BAC pairings acquired a strong taste aversion to SAC by the third CTA trial, as illustrated by the significant difference in SAC drinking between animals given EU training and those that had SAC paired with LiCl or BAC. All of the EU groups that did not receive CS + US pairings did not acquire a CTA, as indicated by high SAC drinking on trail 3, which was significantly greater than their drinking on trial 1. The SAC + LiCl, SAC + BAC 2 mg/kg and SAC + BAC 3 mg/kg groups were all drinking near-zero amounts of SAC on trial 3, which was significantly less than their SAC drinking on trial 1. Drinking on the first conditioning trial was not significantly different between any groups [Mean SAC consumption ± SEM on trial 1 = 4.35 ± 1.22 ml]. Note: A BAC 1 mg/kg group was not used in Experiment 2 because this group did not indicate a disruption of SAC discrimination capabilities in Experiment 1 nor did they demonstrate any possible US effects of BAC exposure in Experiment 1. *Significant difference between EU groups and the following CS + US groups: SAC + LiCl, SAC + BAC 2 mg/kg, and SAC + BAC 3 mg/kg. p < 0.05

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