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Table 1 Comprehensive behavioral test battery of Disc1 mutant mice

From: Comprehensive behavioral analysis of ENU-induced Disc1-Q31L and -L100P mutant mice

Test

Q31L

L100P

 
 

Age (w)

Days

Age (w)

Days

Results

1.Neurological screen

10-17

1-2

11-15

1-3

Figure 1A-D

2.Light/dark transition

11-17

4

12-15

4

Figure 2I-L

3.Open field

11-18

7-9

12-16

8-10

Figure 2A-H

4.Elevated plus maze

12-18

11-12

13-16

11-12

Figure 2M-P

5.Hot plate

12-19

15

13-16

14

Figure 3A

6.Social Interaction

13-19

16

13-17

15

Figure 4A-E

7.Rotarod

13-19

18-19

13-17

16-17

Figure 3B, C

8.Prepulse inhibition

13-20

21

16-19

33

Figure 5E, F

9.Porsolt forced swim

14-20

24-25

17-20

39-40

Figure 5A, B

10.Socialbility/social novelty

15-21

30-35

17-21

43-46

Figure 4F, G

11.T-maze

24-30

94-113

18-22

51-75

Figure 6A-D

12.Tail suspension

27-34

120

23-26

81

Figure 5 C, D

13.Fear conditioning

29-35

128-129

23-27

87-88

Figure 6E-J

  1. Age (w): age of weeks of subjects at the beginning of each test