From: Comprehensive behavioral analysis of ENU-induced Disc1-Q31L and -L100P mutant mice
Test | Q31L | L100P | Â | ||
---|---|---|---|---|---|
 | Age (w) | Days | Age (w) | Days | Results |
1.Neurological screen | 10-17 | 1-2 | 11-15 | 1-3 | Figure 1A-D |
2.Light/dark transition | 11-17 | 4 | 12-15 | 4 | Figure 2I-L |
3.Open field | 11-18 | 7-9 | 12-16 | 8-10 | Figure 2A-H |
4.Elevated plus maze | 12-18 | 11-12 | 13-16 | 11-12 | Figure 2M-P |
5.Hot plate | 12-19 | 15 | 13-16 | 14 | Figure 3A |
6.Social Interaction | 13-19 | 16 | 13-17 | 15 | Figure 4A-E |
7.Rotarod | 13-19 | 18-19 | 13-17 | 16-17 | Figure 3B, C |
8.Prepulse inhibition | 13-20 | 21 | 16-19 | 33 | Figure 5E, F |
9.Porsolt forced swim | 14-20 | 24-25 | 17-20 | 39-40 | Figure 5A, B |
10.Socialbility/social novelty | 15-21 | 30-35 | 17-21 | 43-46 | Figure 4F, G |
11.T-maze | 24-30 | 94-113 | 18-22 | 51-75 | Figure 6A-D |
12.Tail suspension | 27-34 | 120 | 23-26 | 81 | Figure 5 C, D |
13.Fear conditioning | 29-35 | 128-129 | 23-27 | 87-88 | Figure 6E-J |