Table 3 Clinical profiles of age-sex matched patients with the rs12425791 A/A or G/A genotype vs.GG genotype
Rs12425791 genotype | P* | ||
|---|---|---|---|
(A/A or G/A) (n = 62) | (GG) (n = 62) | ||
Age | 68.3 ± 11.7 | 68.3 ± 11.0 | 0.994 |
Sex (male) | 35 (56.5%) | 34 (54.8%) | 0.857 |
Hypertension | 42 (67.7%) | 46 (74.2%) | 0.429 |
Diabetes mellitus | 24 (38.7%) | 24 (38.7%) | 1.000 |
Dyslipidemia | 41 (66.1%) | 47 (75.8%) | 0.235 |
Heart disease | 5 (8.1%) | 2 (3.2%) | 0.439† |
Smoking | 32 (51.6%) | 33 (53.2%) | 0.857 |
Current smoking | 31 (50.0%) | 29 (46.8%) | 0.526 |
Prior medication | |||
Antihypertensives | 21 (33.9%) | 23 (37.1%) | 0.707 |
Antidiabetics | 21 (33.9%) | 24 (38.7%) | 0.575 |
Statins | 19 (30.6%) | 19 (30.6%) | 1.000 |
Antiplatelets | 12 (19.4%) | 12 (19.4%) | 1.000 |
Warfarin | 0 (0.0%) | 1 (1.6%) | 0.496† |
Ischemic stroke subtype‡ | 1.000† | ||
Large artery atherosclerosis | 16 (25.8%) | 17 (27.4%) | |
Small vessel occlusion | 35 (56.5%) | 35 (56.5%) | |
Cardioembolism | 1 (1.6%) | 2 (3.2%) | |
Other determined etiology | 1 (1.6%) | 0 (0.0%) | |
Undetermined etiology | 9 (14.5%) | 8 (12.9%) | |
Premorbid mRS | 1.2 ± 1.6 | 1.0 ± 1.6 | 0.575 |
Admission NIHSS | 4.4 ± 3.6 | 4.5 ± 4.1 | 0.872 |
Discharge NIHSS | 2.7 ± 3.7 | 2.4 ± 2.9 | 0.629 |
NIHSS (admission - discharge) | 1.7 ± 3.3 | 2.1 ± 3.5 | 0.512 |
Discharge mRS | 2.1 ± 1.6 | 2.0 ± 1.6 | 0.612 |
1 year mRS (n = 58 & 62) | 1.2 ± 1.4 | 1.6 ± 1.6 | 0.143 |